Application of Genetic Engineering Technologies for the Study of Pituitary Development and Neoplasms

Acta Histochemica et Cytochemica

Volumn 36, Issue 4, 2003, Pages 249-254

  Osamura, Robert Yoshiyuki ^a   Miyai, Shunsuke ^a   Egashira, Noboru ^a   Takekoshi, Susumu ^a   Yamazaki, Michio ^b   Sanno, Naoko ^b   Teramoto, Akira ^b  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

Gene transfection; Pituitary adenoma; Pituitary gland; Secretory pathway; Transcription factor

Indexed keywords

HORMONE PRECURSOR; PEPTIDE DERIVATIVE; TRANSCRIPTION FACTOR;

ANIMAL CELL; DEVELOPMENT; ENDOCRINE CELL; GENETIC ENGINEERING; HORMONE RELEASE; HORMONE SYNTHESIS; HYPOPHYSIS; HYPOPHYSIS TUMOR; MOUSE; NONHUMAN; REVIEW; SECRETORY GRANULE; TECHNOLOGY;

ANIMALIA;

EID: 0242541990     PISSN: 00445991     EISSN: None     Source Type: Journal    
DOI: 10.1267/ahc.36.249     Document Type: Review

References (30)

1. Asa, S. L., Kovacs, K., Stefaneanu, L., Horvath, E., Billestrup, N., Gonzalez-Manchon, C. and Vale, W. (1992) Pituitary adenomas in mice transgenic for growth hormone-releasing hormone. Endocrinology 131; 2083-2089.
2. Asa, S. L. and Ezzat, S. (2002) The pathogenesis of pituitary tamours. Nat. Rev. Cancer 2; 836-849.
3. Chance, B. (1968) Biological membranes: regulatory functions. Science 160; 1261-1266.
4. Chen, Y. A. and Scheller, R. H. (2001) SNARE-mediated membrane fusion. Nat. Rev. Mol. Cell. Biol. 2; 98-106.
5. Cushman, L. J., Watkins-Chow, D. E., Brinkmeier, M. L., Raetzman, L. T., Radak, A. L., Lloyd, R. V. and Camper, S. A. (2001) Persistent Propl expression delays gonadotrope differentiation and enhances pituitary tumor susceptibility. Hum. Mol. Genet. 10; 1141-1153.
6. El Meskini, R., Jin, L., Marx, R., Bruzzaniti, A., Lee, J., Emeson, R. and Mains, R. (2001) A signal sequence is sufficient for green fluorescent protein to be routed to regulated secretory granules. Endocrinology 142; 864-873.
7. Gil Aguado, A., Sanchez Franco, F., Barbado Hernandez, J., Rodriguez Gonzalez, J., Lopez Barea, F., Arnalich Fernandez, F. and Vazquez Rodriguez, J. J. (1979) Hormonal multiplicity of an apudoma of the lung and pancreas. Characterization of the different peptides in the tumoral extracts (author's transl). Med. Clin. (Barc). 72; 242-247.
8. Halban, P. A. and Irminger, J. C. (1994) Sorting and processing of secretory proteins. Biochem. J. 299; 1-18.
9. Hentges, S. T. and Low, M. J. (2002) Ovarian dependence for pituitary tumorigenesis in D2 dopamine receptor-deficient mice. Endocrinology 143; 4536-4543.
10. Kelly, R. B. (1985) Pathways of protein secretion in eukaryotes. Science 230; 25-32.
11. Kim, T., Tao-Cheng, J. H., Eiden, L. E. and Loh, Y. P. (2002) Large dense-core secretory granule biogenesis is under the control of chromogranin A in neuroendocrine cells. Ann. N Y Acad. Sci. 971; 323-331.
12. Kurotani, R., Yoshimura, S., Iwasaki, Y., Inoue, K., Teramoto, A. and Osamura, R. Y. (2002) Exogenous expression of Pit-1 in AtT-20 corticotropic cells induces endogenous growth hormone gene transcription. J. Endocrinol. 172; 477-487.
13. Matsuno, A., Katakami, H., Sanno, N., Ogino, Y., Osamura, R. Y., Matsukura, S., Shimizu, N. and Nagashima, T. (1999) Pituitary somatotroph adenoma producing growth hormone (GH)-releasing hormone (GHRH) with an elevated plasma GHRH concentration: a model case for autocrine and paracrine regulation of GH secretion by GHRH. J. Clin. Endocrinol. Metab. 84; 3241-3247.
14. Nakayama, K., Ishida, N., Shirane, M., Inomata, A., Inoue, T., Shishido, N., Horii, I., Loh, D. Y. and Nakayama, K. (1996) Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85; 707-720.
15. Orth, D. N., Guillemin, R., Ling, N. and Nicholson, W. E. (1978) Immunoreactive endorphins, lipotropins and corticotropins in a human nonpituitary tumor: evidence for a common precursor. J. Clin. Endocrinol. Metab. 46; 849-852.
16. Osamura, R. Y., Suemizu, Y., Yoshimura, S., Hori, S., Inada, K., Watanabe, K., Nakai, Y. and Imura, H. (1991) Secretory pathways and processing of human proopiomelanocortin (POMC) using transformed mouse cultured fibroblasts (L cells) and AtT-20 cells by human POMC gene-preembedding immunoelectron microscopic studies. Peptides 12; 503-507.
17. Osamura, R. Y., Tahara, S., Sanno, N., Kurotani, R. and Teramoto, A. (1998) Mechanism of hormone production in pituitary cells and pituitary neoplasms; synergistic actions of transcription factors. Acta Histochem. Cytochem. 32; 107-110.
18. Osamura, R. Y., Tahara, S., Kurotani, R., Sanno, N., Matsuno, A. and Teramoto, A. (2000) Contributions of immunohistochemistry and in situ hybridization to the functional analysis of pituitary adenomas. J. Histochem. Cytochem. 48; 445-458.
19. Pouli, A. E., Kennedy, H. J., Schofield, J. G. and Rutter, G. A. (1998) Insulin targeting to the regulated secretory pathway after fusion with green fluorescent protein and firefly luciferase. Biochem J. 331; 669-675.
20. Sanno, N., Tahara, S., Kurotani, R., Matsuno, A., Teramoto, A. and Osamura, R. Y. (2001) Cytochemical and molecular biological aspects of the pituitary and pituitary adenomas-cell differentiation and transcription factors. Prog. Histochem. Cytochem. 36; 263-299.
21. Sanno, N., Teramoto, A., Osamura, R. Y., Horvath, E., Kovacs, K., Lloyd, R. V. and Scheithauer, B. W. (2003) Pathology of pituitary tumors. Neurosurg. Clin. N Am. 14; 25-39.
22. Schoch, S., Deak, F., Konigstorfer, A., Mozhayeva, M., Sara, Y., Sudhof, T. C. and Kavalali, E. T. (2001) SNARE function analyzed in synaptobrevin/VAMP knockout mice. Science 294; 1117-1122.
23. Scully, K. M. and Rosenfeld, M. G. (2002) Pituitary development: regulatory codes in mammalian organogenesis. Science 295; 2231-2235.
24. Stieber, P., Dienemann, H., Schalhorn, A., Schmitt, U. M., Reinmiedl, J., Hofmann, K. and Yamaguchi, K. (1999) Progastrin-releasing peptide (ProGRP)-a useful marker in small cell lung carcinomas. Anticancer Res. 19; 2673-2678.
25. Tahara, S., Kurotani, R., Ishii, Y., Sanno, N., Teramoto, A. and Osamura, R. Y. (2002) A case of Cushing's disease caused by pituitary adenoma producing adrenocorticotropic hormone and growth hormone concomitantly: aberrant expression of transcription factors NeuroDl and Pit-1 as a proposed mechanism. Mod. Pathol. 15; 1102-1105.
26. Tanaka, S. and Kurosumi, K. (1992) A certain step of proteolytic processing of proopiomelanocortin occurs during the transition between two distinct stages of secretory granule maturation in rat anterior pituitary corticotrophs. Endocrinology 131; 779-786.
27. Thomas, L., Leduc, R., Thorne, B. A., Smeekens, S. P., Steiner, D. F. and Thomas, G. (1991) Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes. Proc. Natl. Acad. Sci. USA 88; 5297-5301.
28. Washbourne, P., Thompson, P. M., Carta, M., Costa, E. T., Mathews, J. R., Lopez-Bendito, G., Molnar, Z., Becher, M. W., Valenzuela, C. F., Partridge, L. D. and Wilson, M. C. (2002) Genetic ablation of the t-SNARE SNAP-25 distinguishes mechanisms of neuroexocytosis. Nat. Neurosci. 5; 19-26.
29. Yaekura, K., Julyan, R., Wicksteed, B. L., Hays, L. B., Alarcon, C., Sommers, S., Poitout, V., Baskin, D. G., Wang, Y., Philipson, L. H. and Rhodes, C. J. (2003) Insulin secretory deficiency and glucose intolerance in Rab3A null mice. J. Biol. Chem. 278; 9715-9721.
30. Yu, S., Asa, S. L. and Ezzat, S. (2002) Fibroblast growth factor receptor 4 is a target for the zinc-finger transcription factor Ikaros in the pituitary. Mol. Endocrinol. 16; 1069-1078.