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Volumn 4, Issue 1, 2003, Pages 11-19

First-line therapy and mitochondrial damage: Different nucleosides, different findings

Author keywords

HAART; HIV; Hyperlactatemia; Lactate; Lactic acidosis; Mitochondrial toxicity; Nucleoside analogues

Indexed keywords

ABACAVIR; ALKALINE PHOSPHATASE; AMYLASE; ANTIRETROVIRUS AGENT; CD4 ANTIGEN; DIDANOSINE; EFAVIRENZ; GAMMA GLUTAMYLTRANSFERASE; LACTATE DEHYDROGENASE; LACTIC ACID; LAMIVUDINE; LAMIVUDINE PLUS ZIDOVUDINE; LOPINAVIR PLUS RITONAVIR; NELFINAVIR; NEVIRAPINE; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; VIRUS RNA; ZALCITABINE;

EID: 0242500956     PISSN: 15284336     EISSN: None     Source Type: Journal    
DOI: 10.1310/HF1J-3P6K-1K9H-AGPY     Document Type: Article
Times cited : (34)

References (42)
  • 1
    • 0034699898 scopus 로고    scopus 로고
    • Adverse effects of antiretroviral therapy
    • Carr A, Cooper D. Adverse effects of antiretroviral therapy. Lancet. 2000;356:1423-1430.
    • (2000) Lancet , vol.356 , pp. 1423-1430
    • Carr, A.1    Cooper, D.2
  • 2
    • 0035204053 scopus 로고    scopus 로고
    • Lipodystrophy syndrome: Diagnostic, clinic and therapeutic aspects
    • Blanco F, Carr A. Lipodystrophy syndrome: diagnostic, clinic and therapeutic aspects. AIDS Rev. 2001;3:98-105.
    • (2001) AIDS Rev. , vol.3 , pp. 98-105
    • Blanco, F.1    Carr, A.2
  • 3
    • 0032189850 scopus 로고    scopus 로고
    • Adverse effects of reverse transcriptase inhibitors: Mitochondrial toxicity as a common pathway
    • Brinkmann K, ter Hofstede H, Burger D, Smeitink J, Koopmans P. Adverse effects of reverse transcriptase inhibitors: mitochondrial toxicity as a common pathway. AIDS. 1998;12:1735-1744.
    • (1998) AIDS , vol.12 , pp. 1735-1744
    • Brinkmann, K.1    ter Hofstede, H.2    Burger, D.3    Smeitink, J.4    Koopmans, P.5
  • 4
    • 0034956253 scopus 로고    scopus 로고
    • Mitochondrial toxicity and HIV therapy
    • White A. Mitochondrial toxicity and HIV therapy. Sex Transmit Inf. 2001;77:158-173.
    • (2001) Sex. Transmit. Inf. , vol.77 , pp. 158-173
    • White, A.1
  • 5
    • 0037158613 scopus 로고    scopus 로고
    • Another surprise from the mitochondrial genome
    • Sanders R. Another surprise from the mitochondrial genome. N Engl J Med. 2002;347:609-611.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 609-611
    • Sanders, R.1
  • 6
    • 0035202444 scopus 로고    scopus 로고
    • Hyperlactatemia and lactic acidosis during antiretroviral therapy: Causes, management and possible etiologies
    • Moyle G. Hyperlactatemia and lactic acidosis during antiretroviral therapy: causes, management and possible etiologies. AIDS Rev. 2001;3:150-156.
    • (2001) AIDS Rev. , vol.3 , pp. 150-156
    • Moyle, G.1
  • 7
    • 0033935975 scopus 로고    scopus 로고
    • Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity
    • Kakuda T. Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity. Clin Ther. 2000;22:685-708.
    • (2000) Clin. Ther. , vol.22 , pp. 685-708
    • Kakuda, T.1
  • 8
    • 0035853430 scopus 로고    scopus 로고
    • Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy
    • John M, Moore C, James I, et al. Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy. AIDS. 2001;15:717-723.
    • (2001) AIDS , vol.15 , pp. 717-723
    • John, M.1    Moore, C.2    James, I.3
  • 9
    • 0035577787 scopus 로고    scopus 로고
    • Hyperlactatemia and antiretroviral therapy: The Swiss Cohort Study
    • Boubaker K, Flepp M, Sudre P, et al. Hyperlactatemia and antiretroviral therapy: the Swiss Cohort Study. Clin Infect Dis. 2001;33:1931-1937.
    • (2001) Clin. Infect. Dis. , vol.33 , pp. 1931-1937
    • Boubaker, K.1    Flepp, M.2    Sudre, P.3
  • 10
    • 0037024753 scopus 로고    scopus 로고
    • Hyperlactatemia and lactic acidosis during antiretroviral therapy: Relevance, reproducibility and possible risk factors
    • Moyle GJ, Datta D, Mandalia S, Morlese J, Asboe D, Gazzard B. Hyperlactatemia and lactic acidosis during antiretroviral therapy: relevance, reproducibility and possible risk factors. AIDS. 2002;16:1341-1349.
    • (2002) AIDS , vol.16 , pp. 1341-1349
    • Moyle, G.J.1    Datta, D.2    Mandalia, S.3    Morlese, J.4    Asboe, D.5    Gazzard, B.6
  • 11
    • 0027012527 scopus 로고
    • Chronic lactic acidosis in a patient with AIDS and mitochondrial myopathy: Biochemical studies
    • Gopinath R, Hutcheon M, Cheemer-Dhadli S, Halperin M. Chronic lactic acidosis in a patient with AIDS and mitochondrial myopathy: biochemical studies. J Am Soc Nephrol. 1992;3:1212-1219.
    • (1992) J. Am. Soc. Nephrol. , vol.3 , pp. 1212-1219
    • Gopinath, R.1    Hutcheon, M.2    Cheemer-Dhadli, S.3    Halperin, M.4
  • 13
    • 0000199664 scopus 로고    scopus 로고
    • Mitochondrial toxicity of nucleoside analogue reverse transcriptase inhibitors: Lactic acidosis, risk factors and therapeutic options
    • Brinkman K, Hofstede H. Mitochondrial toxicity of nucleoside analogue reverse transcriptase inhibitors: lactic acidosis, risk factors and therapeutic options. AIDS Rev. 1999;1:141-148.
    • (1999) AIDS Rev. , vol.1 , pp. 141-148
    • Brinkman, K.1    Hofstede, H.2
  • 14
    • 0037087075 scopus 로고    scopus 로고
    • Severe nucleoside-associated lactic acidosis in HIV-infected patients: Report of 12 cases and review of the literature
    • Falcó V, Rodríguez D, Ribera E, et al. Severe nucleoside-associated lactic acidosis in HIV-infected patients: report of 12 cases and review of the literature. Clin Infect Dis. 2002;34:838-846.
    • (2002) Clin. Infect. Dis. , vol.34 , pp. 838-846
    • Falcó, V.1    Rodríguez, D.2    Ribera, E.3
  • 15
    • 0033180064 scopus 로고    scopus 로고
    • Hepatocellular mitochondrial alterations in patients with chronic hepatitis C: Ultrastructural and biochemical findings
    • Barbaro G, Lorenzo G, Asti A, et al. Hepatocellular mitochondrial alterations in patients with chronic hepatitis C: ultrastructural and biochemical findings. Am J Gastroenterol. 1999;94:2198-2205.
    • (1999) Am. J. Gastroenterol. , vol.94 , pp. 2198-2205
    • Barbaro, G.1    Lorenzo, G.2    Asti, A.3
  • 16
    • 0033391005 scopus 로고    scopus 로고
    • A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy
    • Saint-Marc T, Partisani M, Pizot-Martin I, et al. A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy. AIDS. 1999;13:1659-1667.
    • (1999) AIDS , vol.13 , pp. 1659-1667
    • Saint-Marc, T.1    Partisani, M.2    Pizot-Martin, I.3
  • 17
    • 0034008520 scopus 로고    scopus 로고
    • A syndrome of lipoatrophy, lactic acidemia and liver dysfunction associated with HIV nucleoside analogue therapy: Contribution to protease inhibitor-related lipodystrophy syndrome
    • Carr A, Miller J, Law M, Cooper D. A syndrome of lipoatrophy, lactic acidemia and liver dysfunction associated with HIV nucleoside analogue therapy: contribution to protease inhibitor-related lipodystrophy syndrome. AIDS. 2000;14:F25-F32.
    • (2000) AIDS. , vol.14
    • Carr, A.1    Miller, J.2    Law, M.3    Cooper, D.4
  • 18
    • 0033924871 scopus 로고    scopus 로고
    • Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection
    • Mallal S, John M, Moore C, James I, McKinnon E. Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection. AIDS. 2000;14:1309-1316.
    • (2000) AIDS , vol.14 , pp. 1309-1316
    • Mallal, S.1    John, M.2    Moore, C.3    James, I.4    McKinnon, E.5
  • 19
    • 0035822947 scopus 로고    scopus 로고
    • Mitochondrial involvement in antiretroviral therapy-related lipodystrophy
    • Gómez M, Miró O, Pedrol E, et al. Mitochondrial involvement in antiretroviral therapy-related lipodystrophy. AIDS. 2001;15:1643-1651.
    • (2001) AIDS , vol.15 , pp. 1643-1651
    • Gómez, M.1    Miró, O.2    Pedrol, E.3
  • 20
    • 0035964717 scopus 로고    scopus 로고
    • Mitochondrial DNA decrease in subcutaneous adipose tissue of HIV-infected individuals with peripheral lipoatrophy
    • Shikuma C, Ningjie H, Milne C, et al. Mitochondrial DNA decrease in subcutaneous adipose tissue of HIV-infected individuals with peripheral lipoatrophy. AIDS. 2001;15:1801-1809.
    • (2001) AIDS , vol.15 , pp. 1801-1809
    • Shikuma, C.1    Ningjie, H.2    Milne, C.3
  • 21
    • 0036471555 scopus 로고    scopus 로고
    • Evidence of nucleoside analogue reverse transcriptase inhibitor-associated genetic and structural defects of mitochondria in adipose tissue of HIV-infected patients
    • Walker U, Bickel M, Volksbeck S, et al. Evidence of nucleoside analogue reverse transcriptase inhibitor-associated genetic and structural defects of mitochondria in adipose tissue of HIV-infected patients. J Acquir Immune Defic Syndr. 2002;29:117-121.
    • (2002) J. Acquir. Immune. Defic. Syndr. , vol.29 , pp. 117-121
    • Walker, U.1    Bickel, M.2    Volksbeck, S.3
  • 22
    • 0034685037 scopus 로고    scopus 로고
    • Antiretroviral therapy in adults: Updated recommendations of the International AIDS Society-USA Panel
    • Carpenter C, Cooper D, Fischl M, et al. Antiretroviral therapy in adults: updated recommendations of the International AIDS Society-USA Panel. JAMA. 2000;283:381-390.
    • (2000) JAMA , vol.283 , pp. 381-390
    • Carpenter, C.1    Cooper, D.2    Fischl, M.3
  • 23
    • 0037055025 scopus 로고    scopus 로고
    • Antiretroviral treatment for adult HIV infection in 2002: Updated recommendations of the International AIDS Society-USA Panel
    • Yeni P, Hammer S, Carpenter C, et al. Antiretroviral treatment for adult HIV infection in 2002: updated recommendations of the International AIDS Society-USA Panel. JAMA. 2002;288:222-235.
    • (2002) JAMA , vol.288 , pp. 222-235
    • Yeni, P.1    Hammer, S.2    Carpenter, C.3
  • 24
    • 0036629840 scopus 로고    scopus 로고
    • NNRTI plus PI combinations in the perspective of nucleoside-sparing or nucleoside-failing antiretroviral regimens
    • Joly V, Descamps D, Yeni P. NNRTI plus PI combinations in the perspective of nucleoside-sparing or nucleoside-failing antiretroviral regimens. AIDS Rev. 2002;4:128-139.
    • (2002) AIDS Rev. , vol.4 , pp. 128-139
    • Joly, V.1    Descamps, D.2    Yeni, P.3
  • 25
    • 0242529051 scopus 로고    scopus 로고
    • Insights into the reasons for discontinuation of the first HAART regimen in a cohort of antiretroviral-naive patients
    • D'Arminio-Monforte A, Cozzi-Lepri A, Rezza G, et al. Insights into the reasons for discontinuation of the first HAART regimen in a cohort of antiretroviral-naive patients. AIDS. 2000;14:499-507.
    • (2000) AIDS , vol.14 , pp. 499-507
    • D'Arminio-Monforte, A.1    Cozzi-Lepri, A.2    Rezza, G.3
  • 26
    • 0037082994 scopus 로고    scopus 로고
    • Lactacidemia in asymptomatic HIV-infected subjects receiving nucleoside reverse transcriptase inhibitors
    • Boffito M, Marietti G, Audagnotto S, Raiter R, Di Perri G. Lactacidemia in asymptomatic HIV-infected subjects receiving nucleoside reverse transcriptase inhibitors. Clin Infect Dis. 2002;34:558-559.
    • (2002) Clin. Infect. Dis. , vol.34 , pp. 558-559
    • Boffito, M.1    Marietti, G.2    Audagnotto, S.3    Raiter, R.4    Di Perri, G.5
  • 27
    • 0034456472 scopus 로고    scopus 로고
    • Hyperlactatemia and hepatic abnormalities in ten HIV-infected patients receiving nucleoside combination regimens
    • Lonergan J, Behling C, Pfander H, Hassanein T, Mathews W. Hyperlactatemia and hepatic abnormalities in ten HIV-infected patients receiving nucleoside combination regimens. Clin Infect Dis. 2000;31:162-166.
    • (2000) Clin. Infect. Dis. , vol.31 , pp. 162-166
    • Lonergan, J.1    Behling, C.2    Pfander, H.3    Hassanein, T.4    Mathews, W.5
  • 28
    • 0034493575 scopus 로고    scopus 로고
    • Symptomatic hyperlactatemia: An emerging complication of antiretroviral therapy
    • Gérard Y, Maulin L, Yazdanpanah Y, et al. Symptomatic hyperlactatemia: an emerging complication of antiretroviral therapy. AIDS. 2000;14:2723-2730.
    • (2000) AIDS. , vol.14 , pp. 2723-2730
    • Gérard, Y.1    Maulin, L.2    Yazdanpanah, Y.3
  • 29
    • 0035853375 scopus 로고    scopus 로고
    • Management of hyperlactatemia: No need for routine lactate measurements
    • Brinkmann K. Management of hyperlactatemia: no need for routine lactate measurements. AIDS. 2001;15:795-797.
    • (2001) AIDS , vol.15 , pp. 795-797
    • Brinkmann, K.1
  • 30
    • 0037055028 scopus 로고    scopus 로고
    • Abacavir substitution for nucleoside analogs in patients with HIV lipoatrophy. A randomized trial
    • Carr A, Workman C, Smith D, et al. Abacavir substitution for nucleoside analogs in patients with HIV lipoatrophy. A randomized trial. JAMA. 2002;288:207-215.
    • (2002) JAMA , vol.288 , pp. 207-215
    • Carr, A.1    Workman, C.2    Smith, D.3
  • 31
    • 0037964275 scopus 로고    scopus 로고
    • Replacing stavudine by abacavir reduces lactate levels and may improve lipoatrophy
    • In press
    • García-Benayas T, Blanco F, Soriano V, González-Lahoz J. Replacing stavudine by abacavir reduces lactate levels and may improve lipoatrophy. AIDS. In press.
    • AIDS
    • García-Benayas, T.1    Blanco, F.2    Soriano, V.3    González-Lahoz, J.4
  • 32
    • 0242529052 scopus 로고    scopus 로고
    • Prevalence, etiology and long-term follow-up of asymptomatic, HIV-infected patients with hyperamylasemia
    • Program and abstracts of the XIV International AIDS Conference; July 7-12, Barcelona, Spain. Abstract MoPeB3164
    • Boyle B, Basuk P, Emancipator K. Prevalence, etiology and long-term follow-up of asymptomatic, HIV-infected patients with hyperamylasemia. In: Program and abstracts of the XIV International AIDS Conference; July 7-12, 2002; Barcelona, Spain. Abstract MoPeB3164.
    • (2002)
    • Boyle, B.1    Basuk, P.2    Emancipator, K.3
  • 33
    • 0242613771 scopus 로고    scopus 로고
    • Incidence of pancreatitis in HIV-infected patients on nucleoside RTIs
    • Program and abstracts of the Eighth Conference on Retroviruses and Opportunistic Infections; February 4-8, Chicago, USA. Abstract 620
    • Moore R, Keruly J, Chaisson R. Incidence of pancreatitis in HIV-infected patients on nucleoside RTIs. In: Program and abstracts of the Eighth Conference on Retroviruses and Opportunistic Infections; February 4-8, 2001; Chicago, USA. Abstract 620.
    • (2001)
    • Moore, R.1    Keruly, J.2    Chaisson, R.3
  • 34
    • 0025133424 scopus 로고
    • Pearson's marrow-pancreas syndrome. A multisystem mitochondrial disorder in infancy
    • Rotig A, Cormier V, Blanche S, et al. Pearson's marrow-pancreas syndrome. A multisystem mitochondrial disorder in infancy. J Clin Invest. 1990;86:1601-1608.
    • (1990) J. Clin. Invest. , vol.86 , pp. 1601-1608
    • Rotig, A.1    Cormier, V.2    Blanche, S.3
  • 35
    • 0032816323 scopus 로고    scopus 로고
    • Acute pancreatitis with severe lactic acidosis in an HIV-infected patient on didanosine therapy
    • Allaouchiche B, Duflo F, Cotte L, et al. Acute pancreatitis with severe lactic acidosis in an HIV-infected patient on didanosine therapy. J Antimicrob Chemother. 1999;44:137-138.
    • (1999) J. Antimicrob. Chemother. , vol.44 , pp. 137-138
    • Allaouchiche, B.1    Duflo, F.2    Cotte, L.3
  • 36
    • 0035577396 scopus 로고    scopus 로고
    • Symptomatic lactic acidosis in hospitalized antiretroviral-treated patients with HIV infection: A report of 12 cases
    • Coghlan M, Somadossi JP, Jhala N, Many W, Saag M, Johnson V. Symptomatic lactic acidosis in hospitalized antiretroviral-treated patients with HIV infection: a report of 12 cases. Clin Infect Dis. 2001;33:1914-1921.
    • (2001) Clin. Infect. Dis. , vol.33 , pp. 1914-1921
    • Coghlan, M.1    Somadossi, J.P.2    Jhala, N.3    Many, W.4    Saag, M.5    Johnson, V.6
  • 37
    • 0028335113 scopus 로고
    • Fulminant hepatitis with severe lactate acidosis in HIV-1-infected patients on didanosine therapy
    • Bissuel F, Brunell F, Habersetzer F, et al. Fulminant hepatitis with severe lactate acidosis in HIV-1-infected patients on didanosine therapy. J Intern Med. 1994;235:367-372.
    • (1994) J. Intern. Med. , vol.235 , pp. 367-372
    • Bissuel, F.1    Brunell, F.2    Habersetzer, F.3
  • 38
    • 0034031191 scopus 로고    scopus 로고
    • Accelerated bone mineral loss in HIV-infected patients receiving potent antiretroviral therapy
    • Tebas P, Powderly W, Claxton S, et al. Accelerated bone mineral loss in HIV-infected patients receiving potent antiretroviral therapy. AIDS. 2000;14:F63-F67.
    • (2000) AIDS , vol.14
    • Tebas, P.1    Powderly, W.2    Claxton, S.3
  • 39
    • 0035199022 scopus 로고    scopus 로고
    • Bone abnormalities in HIV-infected patients on HAART
    • Mondy K, Tebas P. Bone abnormalities in HIV-infected patients on HAART. AIDS Rev. 2001;3:82-88.
    • (2001) AIDS Rev. , vol.3 , pp. 82-88
    • Mondy, K.1    Tebas, P.2
  • 40
    • 0035853371 scopus 로고    scopus 로고
    • Osteopenia in HIV-infected men: Association with asymptomatic lactic acidemia and lower weight pre-antiretroviral therapy
    • Carr A, Miller J, Eisman J, Cooper D. Osteopenia in HIV-infected men: association with asymptomatic lactic acidemia and lower weight pre-antiretroviral therapy. AIDS. 2001;15:703-709.
    • (2001) AIDS , vol.15 , pp. 703-709
    • Carr, A.1    Miller, J.2    Eisman, J.3    Cooper, D.4
  • 41
    • 0036683037 scopus 로고    scopus 로고
    • Antiretroviral treatment patterns and incident HIV-associated morphologic and lipid abnormalities in a population-based cohort
    • Heath K, Hogg R, Singer J, et al. Antiretroviral treatment patterns and incident HIV-associated morphologic and lipid abnormalities in a population-based cohort. J Acquir Immune Defic Syndr. 2002;30:440-447.
    • (2002) J. Acquir. Immune. Defic. Syndr. , vol.30 , pp. 440-447
    • Heath, K.1    Hogg, R.2    Singer, J.3
  • 42
    • 0035941778 scopus 로고    scopus 로고
    • Risk of lipodystrophy in HIV-1-infected patients treated with protease inhibitors: A prospective cohort study
    • Martínez E, Mocroft A, García-Viejo M, et al. Risk of lipodystrophy in HIV-1-infected patients treated with protease inhibitors: a prospective cohort study. Lancet. 2001;357:592-598.
    • (2001) Lancet , vol.357 , pp. 592-598
    • Martínez, E.1    Mocroft, A.2    García-Viejo, M.3


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