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Volumn 285, Issue 6 54-6, 2003, Pages

Proximal tubular cholesterol loading after mitochondrial, but not glycolytic, blockade

Author keywords

2 deoxyglucose; ABCA1; Antimycin A; LDL receptor; SR B1

Indexed keywords

ANTIMYCIN A1; DEOXYGLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LOW DENSITY LIPOPROTEIN RECEPTOR;

EID: 0242497269     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00187.2003     Document Type: Article
Times cited : (13)

References (30)
  • 2
    • 0037062481 scopus 로고    scopus 로고
    • 3-Hydroxymethylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathway: Implications for diabetic nephropathy
    • Danesh FR, Sadeghi MM, Amro N, Phillips C, Zeng L, Sahai A, and Kanwar YS. 3-Hydroxymethylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathway: implications for diabetic nephropathy. Proc Natl Acad Sci USA 99: 8301-8305, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8301-8305
    • Danesh, F.R.1    Sadeghi, M.M.2    Amro, N.3    Phillips, C.4    Zeng, L.5    Sahai, A.6    Kanwar, Y.S.7
  • 3
    • 0032851111 scopus 로고    scopus 로고
    • Sterols and isoprenoids: Signaling molecules derived from the cholesterol biosynthetic pathway
    • Edwards PA and Ericsson J. Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway. Annu Rev Biochem 68: 157-185, 1999.
    • (1999) Annu Rev Biochem , vol.68 , pp. 157-185
    • Edwards, P.A.1    Ericsson, J.2
  • 4
    • 0035176477 scopus 로고    scopus 로고
    • Cellular overexpression of heme oxygenase-1 up-regulates p21, and confers resistance to apoptosis
    • Inguaggiato P, Gonzalez-Michaca L, Croatt AJ, Haggard JJ, Alam J, and Nath KA. Cellular overexpression of heme oxygenase-1 up-regulates p21, and confers resistance to apoptosis. Kidney Int 60: 2181-2191, 2001.
    • (2001) Kidney Int , vol.60 , pp. 2181-2191
    • Inguaggiato, P.1    Gonzalez-Michaca, L.2    Croatt, A.J.3    Haggard, J.J.4    Alam, J.5    Nath, K.A.6
  • 5
    • 0029056908 scopus 로고
    • Sphingosine: A mediator of acute renal tubular injury, and subsequent cytoresistance
    • Iwata M, Herrington J, and Zager RA. Sphingosine: a mediator of acute renal tubular injury, and subsequent cytoresistance. Proc Nat Acad Sci USA 92: 8970-8974, 1995.
    • (1995) Proc Nat Acad Sci USA , vol.92 , pp. 8970-8974
    • Iwata, M.1    Herrington, J.2    Zager, R.A.3
  • 6
    • 0029047757 scopus 로고
    • Protein synthesis inhibition induces cytoresistance in cultured proximal tubular (HK-2) cells
    • Iwata M, Herrington JB, and Zager RA. Protein synthesis inhibition induces cytoresistance in cultured proximal tubular (HK-2) cells. Am J Physiol Renal Fluid Electrolyte Physiol 268: F1154-F1163, 1995.
    • (1995) Am J Physiol Renal Fluid Electrolyte Physiol , vol.268
    • Iwata, M.1    Herrington, J.B.2    Zager, R.A.3
  • 7
    • 0029744914 scopus 로고    scopus 로고
    • Myoglobin induces transient growth arrest in cultured human proximal tubular cells
    • Iwata M and Zager RA. Myoglobin induces transient growth arrest in cultured human proximal tubular cells. Kidney Int 50: 796-804, 1996.
    • (1996) Kidney Int , vol.50 , pp. 796-804
    • Iwata, M.1    Zager, R.A.2
  • 8
    • 0037222320 scopus 로고    scopus 로고
    • Experimental glomerulopathy alters renal cortical cholesterol, S.R-B1, ABCA1, and HMG CoA reductase expression
    • Johnson ACM, Yabu J, Hanson S, Shah VO, and Zager RA. Experimental glomerulopathy alters renal cortical cholesterol, S.R-B1, ABCA1, and HMG CoA reductase expression. Am J Pathol 162: 273-281, 2003.
    • (2003) Am J Pathol , vol.162 , pp. 273-281
    • Johnson, A.C.M.1    Yabu, J.2    Hanson, S.3    Shah, V.O.4    Zager, R.A.5
  • 10
    • 0030665658 scopus 로고    scopus 로고
    • Lysophosphatidic acid: A novel growth, and survival factor for renal proximal tubular cells
    • Levine JS, Koh JS, Triaca V, and Lieberthal W. Lysophosphatidic acid: a novel growth, and survival factor for renal proximal tubular cells. Am J Physiol Renal Physiol 273: F575-F585, 1997.
    • (1997) Am J Physiol Renal Physiol , vol.273
    • Levine, J.S.1    Koh, J.S.2    Triaca, V.3    Lieberthal, W.4
  • 11
    • 0038121035 scopus 로고    scopus 로고
    • Cholesterol modulating agents kill acute myeloid leukemia cells, and sensitize them to therapeutics by blocking adaptive cholesterol responses
    • Li H, Appelbaum F, Zager RA, and Banker DE. Cholesterol modulating agents kill acute myeloid leukemia cells, and sensitize them to therapeutics by blocking adaptive cholesterol responses. Blood 101: 3628-3634, 2003.
    • (2003) Blood , vol.101 , pp. 3628-3634
    • Li, H.1    Appelbaum, F.2    Zager, R.A.3    Banker, D.E.4
  • 13
    • 0031036845 scopus 로고    scopus 로고
    • Geranylgeroniol potentiates lovastatin inhibition of oncogenic H-Ras processing, and signaling while preventing cytotoxicity
    • McGuire TF and Sebti SM. Geranylgeroniol potentiates lovastatin inhibition of oncogenic H-Ras processing, and signaling while preventing cytotoxicity. Oncogene 14: 305-312, 1997.
    • (1997) Oncogene , vol.14 , pp. 305-312
    • McGuire, T.F.1    Sebti, S.M.2
  • 16
    • 0012689561 scopus 로고    scopus 로고
    • Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with RAS hotspot mutations or overexpression
    • Stirewalt DL, Appelbaum FR, Willman CL, Zager RA, and Banker DE. Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with RAS hotspot mutations or overexpression. Leuk Res 1572: 1-13, 2002.
    • (2002) Leuk Res , vol.1572 , pp. 1-13
    • Stirewalt, D.L.1    Appelbaum, F.R.2    Willman, C.L.3    Zager, R.A.4    Banker, D.E.5
  • 18
    • 0036556790 scopus 로고    scopus 로고
    • Hsp72 expression enhances survival in adenosine triphosphate-depleted renal epithelial cells
    • Wang YH, Knowlton AA, Li FH, and Borkan SC. Hsp72 expression enhances survival in adenosine triphosphate-depleted renal epithelial cells. Cell Stress Chaperones 7: 137-145, 2002.
    • (2002) Cell Stress Chaperones , vol.7 , pp. 137-145
    • Wang, Y.H.1    Knowlton, A.A.2    Li, F.H.3    Borkan, S.C.4
  • 19
    • 0033916957 scopus 로고    scopus 로고
    • Plasma membrane cholesterol: A critical determinant of cellular energetics, and tubular resistance to attack
    • Zager RA. Plasma membrane cholesterol: a critical determinant of cellular energetics, and tubular resistance to attack. Kidney Int 58: 193-205, 2000.
    • (2000) Kidney Int , vol.58 , pp. 193-205
    • Zager, R.A.1
  • 20
    • 0035720563 scopus 로고    scopus 로고
    • P glycoprotein-mediated cholesterol cycling: A potentially important determinant of proximal tubular cell viability
    • Zager RA. P glycoprotein-mediated cholesterol cycling: a potentially important determinant of proximal tubular cell viability. Kidney Int 60: 944-956, 2001.
    • (2001) Kidney Int , vol.60 , pp. 944-956
    • Zager, R.A.1
  • 21
    • 0029661827 scopus 로고    scopus 로고
    • 2 induced cytoprotection of proximal tubules: Potential determinants, and specificity for ATP depletion injury
    • 2 induced cytoprotection of proximal tubules: potential determinants, and specificity for ATP depletion injury. J Am Soc Nephrol 7: 64-72, 1996.
    • (1996) J Am Soc Nephrol , vol.7 , pp. 64-72
    • Zager, R.A.1    Burkhart, K.M.2    Conrad, D.S.3    Gmur, D.J.4    Iwata, M.5
  • 22
    • 0032746959 scopus 로고    scopus 로고
    • Increased proximal tubular cholesterol content: Implications for cell injury, and "acquired cytoresistance"
    • Zager RA, Burkhart KM, Johnson AC, and Sacks BM. Increased proximal tubular cholesterol content: implications for cell injury, and "acquired cytoresistance." Kidney Int 56: 1788-1797, 1999.
    • (1999) Kidney Int , vol.56 , pp. 1788-1797
    • Zager, R.A.1    Burkhart, K.M.2    Johnson, A.C.3    Sacks, B.M.4
  • 23
    • 0025858223 scopus 로고
    • Temperature effects on ischemic, and hypoxic renal proximal tubular injury
    • Zager RA, Gmur DJ, Bredl CR, and Eng MJ. Temperature effects on ischemic, and hypoxic renal proximal tubular injury. Lab Invest 64: 766-776, 1991.
    • (1991) Lab Invest , vol.64 , pp. 766-776
    • Zager, R.A.1    Gmur, D.J.2    Bredl, C.R.3    Eng, M.J.4
  • 24
    • 0035187386 scopus 로고    scopus 로고
    • Renal cortical cholesterol accumulation is an integral component of the systemic stress response
    • Zager RA and Johnson A. Renal cortical cholesterol accumulation is an integral component of the systemic stress response. Kidney Int 60: 2299-2310, 2001.
    • (2001) Kidney Int , vol.60 , pp. 2299-2310
    • Zager, R.A.1    Johnson, A.2
  • 25
    • 0035049276 scopus 로고    scopus 로고
    • Cholesterol ester accumulation: An immediate consequence of acute in vivo ischemic renal injury
    • Zager RA, Johnson A, Anderson K, and Wright S. Cholesterol ester accumulation: an immediate consequence of acute in vivo ischemic renal injury. Kidney Int 59: 1750-1761, 2001.
    • (2001) Kidney Int , vol.59 , pp. 1750-1761
    • Zager, R.A.1    Johnson, A.2    Anderson, K.3    Wright, S.4
  • 26
    • 0037213064 scopus 로고    scopus 로고
    • Sepsis syndrome stimulates proximal tubule cholesterol synthesis, and suppresses the SR-B1 cholesterol transporter
    • Zager RA, Johnson A, and Hanson SY. Sepsis syndrome stimulates proximal tubule cholesterol synthesis, and suppresses the SR-B1 cholesterol transporter. Kidney Int 63: 123-133, 2003.
    • (2003) Kidney Int , vol.63 , pp. 123-133
    • Zager, R.A.1    Johnson, A.2    Hanson, S.Y.3
  • 27
    • 0036232985 scopus 로고    scopus 로고
    • Altered cholesterol localization, and caveolin expression during the evolution of acute renal failure
    • Zager RA, Johnson A, Hanson S, and dela Rosa V. Altered cholesterol localization, and caveolin expression during the evolution of acute renal failure. Kidney Int 61: 1674-1683, 2002.
    • (2002) Kidney Int , vol.61 , pp. 1674-1683
    • Zager, R.A.1    Johnson, A.2    Hanson, S.3    Dela Rosa, V.4
  • 28
    • 0038645852 scopus 로고    scopus 로고
    • Acute tubular injury causes dysregulation of cellular cholesterol transport proteins
    • Zager RA, Johnson ACM, and Hanson SY, and Shah VO. Acute tubular injury causes dysregulation of cellular cholesterol transport proteins. Am J Pathol 163: 313-320, 2003.
    • (2003) Am J Pathol , vol.163 , pp. 313-320
    • Zager, R.A.1    Johnson, A.C.M.2    Hanson, S.Y.3    Shah, V.O.4
  • 29
    • 0034493849 scopus 로고    scopus 로고
    • Changes in free and esterified cholesterol: Hallmarks of acute renal tubular injury and acquired cytoresistance
    • Zager RA and Kalhorn TF. Changes in free and esterified cholesterol: hallmarks of acute renal tubular injury and acquired cytoresistance. Am J Pathol 157: 1007-1016, 2000.
    • (2000) Am J Pathol , vol.157 , pp. 1007-1016
    • Zager, R.A.1    Kalhorn, T.F.2
  • 30
    • 0036966284 scopus 로고    scopus 로고
    • The mevalonate pathway during acute tubular injury. Selected determinants and consequences
    • Zager RA, Shah VO, Shah HV, Zager PA, Johnson AC, and Hanson S. The mevalonate pathway during acute tubular injury. Selected determinants and consequences. Am J Pathol 161: 681-692, 2002.
    • (2002) Am J Pathol , vol.161 , pp. 681-692
    • Zager, R.A.1    Shah, V.O.2    Shah, H.V.3    Zager, P.A.4    Johnson, A.C.5    Hanson, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.