-
1
-
-
0037377144
-
Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2
-
Alam J, Killeen E, Gong P, Naquin R, Hu B, Stewart D, Ingelfinger JR, and Nath KA. Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2. Am J Physiol Renal Physiol 284: F743-F752, 2003.
-
(2003)
Am J Physiol Renal Physiol
, vol.284
-
-
Alam, J.1
Killeen, E.2
Gong, P.3
Naquin, R.4
Hu, B.5
Stewart, D.6
Ingelfinger, J.R.7
Nath, K.A.8
-
2
-
-
0037062481
-
3-Hydroxymethylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathway: Implications for diabetic nephropathy
-
Danesh FR, Sadeghi MM, Amro N, Phillips C, Zeng L, Sahai A, and Kanwar YS. 3-Hydroxymethylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathway: implications for diabetic nephropathy. Proc Natl Acad Sci USA 99: 8301-8305, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8301-8305
-
-
Danesh, F.R.1
Sadeghi, M.M.2
Amro, N.3
Phillips, C.4
Zeng, L.5
Sahai, A.6
Kanwar, Y.S.7
-
3
-
-
0032851111
-
Sterols and isoprenoids: Signaling molecules derived from the cholesterol biosynthetic pathway
-
Edwards PA and Ericsson J. Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway. Annu Rev Biochem 68: 157-185, 1999.
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 157-185
-
-
Edwards, P.A.1
Ericsson, J.2
-
4
-
-
0035176477
-
Cellular overexpression of heme oxygenase-1 up-regulates p21, and confers resistance to apoptosis
-
Inguaggiato P, Gonzalez-Michaca L, Croatt AJ, Haggard JJ, Alam J, and Nath KA. Cellular overexpression of heme oxygenase-1 up-regulates p21, and confers resistance to apoptosis. Kidney Int 60: 2181-2191, 2001.
-
(2001)
Kidney Int
, vol.60
, pp. 2181-2191
-
-
Inguaggiato, P.1
Gonzalez-Michaca, L.2
Croatt, A.J.3
Haggard, J.J.4
Alam, J.5
Nath, K.A.6
-
5
-
-
0029056908
-
Sphingosine: A mediator of acute renal tubular injury, and subsequent cytoresistance
-
Iwata M, Herrington J, and Zager RA. Sphingosine: a mediator of acute renal tubular injury, and subsequent cytoresistance. Proc Nat Acad Sci USA 92: 8970-8974, 1995.
-
(1995)
Proc Nat Acad Sci USA
, vol.92
, pp. 8970-8974
-
-
Iwata, M.1
Herrington, J.2
Zager, R.A.3
-
7
-
-
0029744914
-
Myoglobin induces transient growth arrest in cultured human proximal tubular cells
-
Iwata M and Zager RA. Myoglobin induces transient growth arrest in cultured human proximal tubular cells. Kidney Int 50: 796-804, 1996.
-
(1996)
Kidney Int
, vol.50
, pp. 796-804
-
-
Iwata, M.1
Zager, R.A.2
-
8
-
-
0037222320
-
Experimental glomerulopathy alters renal cortical cholesterol, S.R-B1, ABCA1, and HMG CoA reductase expression
-
Johnson ACM, Yabu J, Hanson S, Shah VO, and Zager RA. Experimental glomerulopathy alters renal cortical cholesterol, S.R-B1, ABCA1, and HMG CoA reductase expression. Am J Pathol 162: 273-281, 2003.
-
(2003)
Am J Pathol
, vol.162
, pp. 273-281
-
-
Johnson, A.C.M.1
Yabu, J.2
Hanson, S.3
Shah, V.O.4
Zager, R.A.5
-
9
-
-
0037369412
-
Heme: A novel inducer of MCP-1 through HO-dependent and HO-independent mechanisms
-
Kanakiriya SK, Croatt AJ, Haggard JJ, Ingelfinger JR, Tang SS, Alam J, and Nath KA. Heme: a novel inducer of MCP-1 through HO-dependent and HO-independent mechanisms. Am J Physiol Renal Physiol 284: F546-F554, 2003.
-
(2003)
Am J Physiol Renal Physiol
, vol.284
-
-
Kanakiriya, S.K.1
Croatt, A.J.2
Haggard, J.J.3
Ingelfinger, J.R.4
Tang, S.S.5
Alam, J.6
Nath, K.A.7
-
10
-
-
0030665658
-
Lysophosphatidic acid: A novel growth, and survival factor for renal proximal tubular cells
-
Levine JS, Koh JS, Triaca V, and Lieberthal W. Lysophosphatidic acid: a novel growth, and survival factor for renal proximal tubular cells. Am J Physiol Renal Physiol 273: F575-F585, 1997.
-
(1997)
Am J Physiol Renal Physiol
, vol.273
-
-
Levine, J.S.1
Koh, J.S.2
Triaca, V.3
Lieberthal, W.4
-
11
-
-
0038121035
-
Cholesterol modulating agents kill acute myeloid leukemia cells, and sensitize them to therapeutics by blocking adaptive cholesterol responses
-
Li H, Appelbaum F, Zager RA, and Banker DE. Cholesterol modulating agents kill acute myeloid leukemia cells, and sensitize them to therapeutics by blocking adaptive cholesterol responses. Blood 101: 3628-3634, 2003.
-
(2003)
Blood
, vol.101
, pp. 3628-3634
-
-
Li, H.1
Appelbaum, F.2
Zager, R.A.3
Banker, D.E.4
-
12
-
-
0036720499
-
Heat stress prevents mitochondrial injury in ATP-depleted renal epithelial cells
-
Li M, Mao HP, Ruchalski KL, Wang YH, Choy W, Schwartz JH, and Borkan SC. Heat stress prevents mitochondrial injury in ATP-depleted renal epithelial cells. Am J Physiol Cell Physiol 283: C917-C926, 2002.
-
(2002)
Am J Physiol Cell Physiol
, vol.283
-
-
Li, M.1
Mao, H.P.2
Ruchalski, K.L.3
Wang, Y.H.4
Choy, W.5
Schwartz, J.H.6
Borkan, S.C.7
-
13
-
-
0031036845
-
Geranylgeroniol potentiates lovastatin inhibition of oncogenic H-Ras processing, and signaling while preventing cytotoxicity
-
McGuire TF and Sebti SM. Geranylgeroniol potentiates lovastatin inhibition of oncogenic H-Ras processing, and signaling while preventing cytotoxicity. Oncogene 14: 305-312, 1997.
-
(1997)
Oncogene
, vol.14
, pp. 305-312
-
-
McGuire, T.F.1
Sebti, S.M.2
-
14
-
-
0028010818
-
HK-2: An immortalized proximal tubule epithelial cell line from normal adult human kidney
-
Ryan MJ, Johnson G, Kirk J, Fuerstenberg SM, Zager RA, and Torok-Storb B. HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney. Kidney Int 45: 48-57, 1994.
-
(1994)
Kidney Int
, vol.45
, pp. 48-57
-
-
Ryan, M.J.1
Johnson, G.2
Kirk, J.3
Fuerstenberg, S.M.4
Zager, R.A.5
Torok-Storb, B.6
-
15
-
-
0031814992
-
Inhibiting geranylgeranylation blocks growth, and promotes apoptosis in pulmonary vascular smooth muscle cells
-
Stark WW Jr, Blaskovich MA, Johnson BA, Qian Y, Vasudevan A, Pitt B, Hamilton AD, Sebto SM, and Davies P. Inhibiting geranylgeranylation blocks growth, and promotes apoptosis in pulmonary vascular smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 275: L55-L63, 1998.
-
(1998)
Am J Physiol Lung Cell Mol Physiol
, vol.275
-
-
Stark Jr., W.W.1
Blaskovich, M.A.2
Johnson, B.A.3
Qian, Y.4
Vasudevan, A.5
Pitt, B.6
Hamilton, A.D.7
Sebto, S.M.8
Davies, P.9
-
16
-
-
0012689561
-
Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with RAS hotspot mutations or overexpression
-
Stirewalt DL, Appelbaum FR, Willman CL, Zager RA, and Banker DE. Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with RAS hotspot mutations or overexpression. Leuk Res 1572: 1-13, 2002.
-
(2002)
Leuk Res
, vol.1572
, pp. 1-13
-
-
Stirewalt, D.L.1
Appelbaum, F.R.2
Willman, C.L.3
Zager, R.A.4
Banker, D.E.5
-
17
-
-
0023877490
-
Beneficial effect of thyroxin in the treatment of ischemic acute renal failure
-
Sutter PM, Thulin G, Stromski M, Ardito T, Gaudio KM, Kashgarian M, and Siegel NJ. Beneficial effect of thyroxin in the treatment of ischemic acute renal failure. Pediatr Nephrol 2: 1-7, 1988.
-
(1988)
Pediatr Nephrol
, vol.2
, pp. 1-7
-
-
Sutter, P.M.1
Thulin, G.2
Stromski, M.3
Ardito, T.4
Gaudio, K.M.5
Kashgarian, M.6
Siegel, N.J.7
-
18
-
-
0036556790
-
Hsp72 expression enhances survival in adenosine triphosphate-depleted renal epithelial cells
-
Wang YH, Knowlton AA, Li FH, and Borkan SC. Hsp72 expression enhances survival in adenosine triphosphate-depleted renal epithelial cells. Cell Stress Chaperones 7: 137-145, 2002.
-
(2002)
Cell Stress Chaperones
, vol.7
, pp. 137-145
-
-
Wang, Y.H.1
Knowlton, A.A.2
Li, F.H.3
Borkan, S.C.4
-
19
-
-
0033916957
-
Plasma membrane cholesterol: A critical determinant of cellular energetics, and tubular resistance to attack
-
Zager RA. Plasma membrane cholesterol: a critical determinant of cellular energetics, and tubular resistance to attack. Kidney Int 58: 193-205, 2000.
-
(2000)
Kidney Int
, vol.58
, pp. 193-205
-
-
Zager, R.A.1
-
20
-
-
0035720563
-
P glycoprotein-mediated cholesterol cycling: A potentially important determinant of proximal tubular cell viability
-
Zager RA. P glycoprotein-mediated cholesterol cycling: a potentially important determinant of proximal tubular cell viability. Kidney Int 60: 944-956, 2001.
-
(2001)
Kidney Int
, vol.60
, pp. 944-956
-
-
Zager, R.A.1
-
21
-
-
0029661827
-
2 induced cytoprotection of proximal tubules: Potential determinants, and specificity for ATP depletion injury
-
2 induced cytoprotection of proximal tubules: potential determinants, and specificity for ATP depletion injury. J Am Soc Nephrol 7: 64-72, 1996.
-
(1996)
J Am Soc Nephrol
, vol.7
, pp. 64-72
-
-
Zager, R.A.1
Burkhart, K.M.2
Conrad, D.S.3
Gmur, D.J.4
Iwata, M.5
-
22
-
-
0032746959
-
Increased proximal tubular cholesterol content: Implications for cell injury, and "acquired cytoresistance"
-
Zager RA, Burkhart KM, Johnson AC, and Sacks BM. Increased proximal tubular cholesterol content: implications for cell injury, and "acquired cytoresistance." Kidney Int 56: 1788-1797, 1999.
-
(1999)
Kidney Int
, vol.56
, pp. 1788-1797
-
-
Zager, R.A.1
Burkhart, K.M.2
Johnson, A.C.3
Sacks, B.M.4
-
23
-
-
0025858223
-
Temperature effects on ischemic, and hypoxic renal proximal tubular injury
-
Zager RA, Gmur DJ, Bredl CR, and Eng MJ. Temperature effects on ischemic, and hypoxic renal proximal tubular injury. Lab Invest 64: 766-776, 1991.
-
(1991)
Lab Invest
, vol.64
, pp. 766-776
-
-
Zager, R.A.1
Gmur, D.J.2
Bredl, C.R.3
Eng, M.J.4
-
24
-
-
0035187386
-
Renal cortical cholesterol accumulation is an integral component of the systemic stress response
-
Zager RA and Johnson A. Renal cortical cholesterol accumulation is an integral component of the systemic stress response. Kidney Int 60: 2299-2310, 2001.
-
(2001)
Kidney Int
, vol.60
, pp. 2299-2310
-
-
Zager, R.A.1
Johnson, A.2
-
25
-
-
0035049276
-
Cholesterol ester accumulation: An immediate consequence of acute in vivo ischemic renal injury
-
Zager RA, Johnson A, Anderson K, and Wright S. Cholesterol ester accumulation: an immediate consequence of acute in vivo ischemic renal injury. Kidney Int 59: 1750-1761, 2001.
-
(2001)
Kidney Int
, vol.59
, pp. 1750-1761
-
-
Zager, R.A.1
Johnson, A.2
Anderson, K.3
Wright, S.4
-
26
-
-
0037213064
-
Sepsis syndrome stimulates proximal tubule cholesterol synthesis, and suppresses the SR-B1 cholesterol transporter
-
Zager RA, Johnson A, and Hanson SY. Sepsis syndrome stimulates proximal tubule cholesterol synthesis, and suppresses the SR-B1 cholesterol transporter. Kidney Int 63: 123-133, 2003.
-
(2003)
Kidney Int
, vol.63
, pp. 123-133
-
-
Zager, R.A.1
Johnson, A.2
Hanson, S.Y.3
-
27
-
-
0036232985
-
Altered cholesterol localization, and caveolin expression during the evolution of acute renal failure
-
Zager RA, Johnson A, Hanson S, and dela Rosa V. Altered cholesterol localization, and caveolin expression during the evolution of acute renal failure. Kidney Int 61: 1674-1683, 2002.
-
(2002)
Kidney Int
, vol.61
, pp. 1674-1683
-
-
Zager, R.A.1
Johnson, A.2
Hanson, S.3
Dela Rosa, V.4
-
28
-
-
0038645852
-
Acute tubular injury causes dysregulation of cellular cholesterol transport proteins
-
Zager RA, Johnson ACM, and Hanson SY, and Shah VO. Acute tubular injury causes dysregulation of cellular cholesterol transport proteins. Am J Pathol 163: 313-320, 2003.
-
(2003)
Am J Pathol
, vol.163
, pp. 313-320
-
-
Zager, R.A.1
Johnson, A.C.M.2
Hanson, S.Y.3
Shah, V.O.4
-
29
-
-
0034493849
-
Changes in free and esterified cholesterol: Hallmarks of acute renal tubular injury and acquired cytoresistance
-
Zager RA and Kalhorn TF. Changes in free and esterified cholesterol: hallmarks of acute renal tubular injury and acquired cytoresistance. Am J Pathol 157: 1007-1016, 2000.
-
(2000)
Am J Pathol
, vol.157
, pp. 1007-1016
-
-
Zager, R.A.1
Kalhorn, T.F.2
-
30
-
-
0036966284
-
The mevalonate pathway during acute tubular injury. Selected determinants and consequences
-
Zager RA, Shah VO, Shah HV, Zager PA, Johnson AC, and Hanson S. The mevalonate pathway during acute tubular injury. Selected determinants and consequences. Am J Pathol 161: 681-692, 2002.
-
(2002)
Am J Pathol
, vol.161
, pp. 681-692
-
-
Zager, R.A.1
Shah, V.O.2
Shah, H.V.3
Zager, P.A.4
Johnson, A.C.5
Hanson, S.6
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