Zoledronic Acid Treatment Results in Retention of Femoral Head Structure After Traumatic Osteonecrosis in Young Wistar Rats

Journal of Bone and Mineral Research

Volumn 18, Issue 11, 2003, Pages 2016-2022

  Little, David G ^a,b   Peat, Rachel A ^a   McEvoy, Anthony ^a   Williams, Paul R ^a   Smith, Elisabeth J ^a,c   Baldock, Paula ^c  

^a CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Bisphosphonates; Bone densitometry; Bone histomorphometry; Modeling and remodeling; Rodent

Indexed keywords

ZOLEDRONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE NECROSIS; BONE REMODELING; BONE STRUCTURE; BONE TURNOVER; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR HEAD; HISTOPATHOLOGY; MORPHOMETRICS; NONHUMAN; POSTOPERATIVE PERIOD; PREOPERATIVE TREATMENT; PROPHYLAXIS; RAT; TREATMENT OUTCOME;

AGE FACTORS; ANIMALS; BONE DENSITY; BONE DEVELOPMENT; DENSITOMETRY, X-RAY; DIPHOSPHONATES; FEMALE; FEMUR HEAD; IMIDAZOLES; OSTEONECROSIS; RATS; RATS, WISTAR; WOUNDS AND INJURIES;

EID: 0242412963     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2003.18.11.2016     Document Type: Article

References (39)

1. Herring JA 1996 Management of Perthes' disease. J Pediatr Orthop 16:1-2.
2. Hall AJ, Barker DJ, Dangerfield PH, Taylor JF 1983 Perthes' disease of the hip in Liverpool. BMJ 287:1757-1759.
3. Moberg A, Rehnberg L 1992 Incidence of Perthes' disease in Uppsala, Sweden. Acta Orthop Scand 63:157-158.
4. Joseph B, Chacko V, Rao BS, Hall AJ 1988 The epidemiology of Perthes' disease in south India. Int J Epidemiol 17:603-607.
5. Stulberg SD, Cooperman DR, Wallensten R 1981 The natural history of Legg-Calve-Perthes disease. J Bone Joint Surg Am 63:1095-1108.
6. Morsy HA 2001 Complications of fracture of the neck of the femur in children. A long-term follow-up study. Injury 32:45-51.
7. Forlin E, Guille JT, Kumar SJ, Rhee KJ 1992 Complications associated with fracture of the neck of the femur in children. J Pediatr Orthop 12:503-509.
8. Morrissy R 1980 Hip fractures in children. Clin Orthop 152:202-210.
9. Loder RT, Richards BS, Shapiro PS, Reznick LR, Aronson DD 1993 Acute slipped capital femoral epiphysis: The importance of physeal stability. J Bone Joint Surg Am 75:1134-1140.
10. Norman D, Reis D, Zinman C, Misselevich I, Boss JH 1998 Vascular deprivation-induced necrosis of the femoral head of the rat. An experimental model of avascular osteonecrosis in the skeletally immature individual or Legg-Perthes disease. Int J Exp Pathol 79:173-181.
11. Levin D, Norman D, Zinman C, Misselevich I, Reis DN, Boss JH 1999 Osteoarthritis-like disorder in rats with vascular deprivation-induced necrosis of the femoral head. Pathol Res Pract 195:637-647.
12. Mose K 1980 Methods of measuring in Legg-Calve-Perthes disease with special regard to the prognosis. Clin Orthop 150:103-109.
13. Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR 1987 Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2:595-610.
14. McNeil PJ, Durbridge TC, Parkinson IH, Moore RJ 1997 Simple method for the simultaneous demonstration of formation and resorption in undecalcified bone embedded in methyl methacrylate. J Histotechnol 20:307-311.
15. Milner PF, Kraus AP, Sebes JI, Sleeper LA, Dukes KA, Embury SH, Bellevue R, Koshy M, Moohr JW, Smith J 1991 Sickle cell disease as a cause of osteonecrosis of the femoral head. N Engl J Med 325:1476-1481.
16. Hemigou P, Bachir D, Galacteros F 2003 The natural history of symptomatic osteonecrosis in adults with sickle-cell disease. J Bone Joint Surg Am 85:500-504.
17. Mattano LA Jr, Sather HN, Trigg ME, Nachman JB 2000 Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: A report from the Children's Cancer Group. J Clin Oncol 18:3262-3272.
18. Ojala AE, Paakko E, Lanning FP, Lanning M 1999 Osteonecrosis during the treatment of childhood acute lymphoblastic leukemia: A prospective MRI study. Med Pediatr Oncol 32:11-17.
19. Wei SY, Esmail AN, Bunin N, Dormans JP 2000 Avascular necrosis in children with acute lymphoblastic leukemia. J Pediatr Orthop 20:331-335.
20. Bentolila V, Boyce TM, Fyhrie DP, Drumb R, Skerry TM, Schaffler MB 1998 Intracortical remodeling in adult rat long bones after fatigue loading. Bone 23:275-281.
21. Verborgt O, Gibson GJ, Schaffler MB 2000 Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo. J Bone Miner Res 15:60-67.
22. Dunford JE, Thompson K, Coxon FP, Luckman SP, Hahn FM, Poulter CD, Ebetino FH, Rogers MJ 2001 Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates. J Pharmacol Exp Ther 296:235-242.
23. Halasy-Nagy JM, Rodan GA, Reszka AA 2001 Inhibition of bone resorption by alendronate and risedronate does not require osteoclast apoptosis. Bone 29:553-559.
24. Astrand J, Aspenberg P 2002 Systemic alendronate prevents resorption of necrotic bone during revascularization. A bone chamber study in rats. BMC Musculoskelet Disord 3:19-23.
25. McAndrew MP, Weinstein SL 1984 A long-term follow-up of Legg-Calve-Perthes disease. J Bone Joint Surg Am 66:860-869.
26. Kucukkaya M, Kabukcuoglu Y, Ozturk I, Kuzgun U 2000 Avascular necrosis of the femoral head in childhood: The results of treatment with articulated distraction method. J Pediatr Orthop 20:722-728.
27. Scherer A, Engelbrecht V, Bernbeck B, May P, Willers R, Gobel U, Modder U 2000 MRI evaluation of aseptic osteonecrosis in children over the course of hyperbaric oxygen therapy. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 172:798-801.
28. Friedlander JK, Weiner DS 2000 Radiographic results of proximal femoral varus osteotomy in Legg-Calve-Perthes disease. J Pediatr Orthop 20:566-571.
29. Daly K, Bruce C, Catterall A 1999 Lateral shelf acetabuloplasty in Perthes' disease. A review of the end of growth. J Bone Joint Surg Br 81:380-384.
30. Scully SP, Aaron RK, Urbaniak JR 1998 Survival analysis of hips treated with core decompression or vascularized fibular grafting because of avascular necrosis. J Bone Joint Surg Am 80:1270-1275.
31. Mont MA, Carbone JJ, Fairbank AC 1996 Core decompression versus nonoperative management for osteonecrosis of the hip. Clin Orthop 324:169-178.
32. Martinez AG, Weinstein SL, Dietz FR 1992 The weight-bearing abduction brace for the treatment of Legg-Perthes disease. J Bone Joint Surg Am 74:12-21.
33. Meehan PL, Angel D, Nelson JM 1992 The Scottish Rite abduction orthosis for the treatment of Legg-Perthes disease. A radiographic analysis. J Bone Joint Surg Am 74:2-12.
34. Robinson HJ Jr, Putter H, Sigmond MB, O'Connor S, Murray KR 1988 Innominate osteotomy in Perthes disease. J Pediatr Orthop 8:426-435.
35. Herring JA 1994 The treatment of Legg-Calve-Perthes disease. A critical review of the literature. J Bone Joint Surg Am 76:448-458.
36. Wenger DR, Ward WT, Herring JA 1991 Legg-Calve-Perthes disease. J Bone Joint Surg Am 73:778-788.
37. Davison BL, Weinstein SL 1992 Hip fractures in children: A long-term follow-up study. J Pediatr Orthop 12:355-358.
38. Hirano T, Iwasaki K, Yamane Y 1988 Osteonecrosis of the femoral head of growing, spontaneously hypertensive rats. Acta Orthop Scand 59:530-535.
39. Reinholz GG, Getz B, Pederson L, Sanders ES, Subramaniam M, Ingle JN, Spelsberg TC 2000 Bisphosphonates directly regulate cell proliferation, differentiation, and gene expression in human osteoblasts. Cancer Res 60:6001-6007.