Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway

Journal of Biological Chemistry

Volumn 278, Issue 44, 2003, Pages 43682-43690

  Sivaraman, J ^a   Li, Yunge ^a   Banks, Jerel ^b   Cane, David E ^b   Matte, Allan ^a   Cygler, Miroslaw ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME KINETICS; ESCHERICHIA COLI; ESTERS; METABOLISM; OXIDATION; REACTION KINETICS;

DECARBOXYLATION;

ENZYMES;

3 AMINO 2 OXOPROPYLPHOSPHATE; 4 HYDROXYTHREONINE; 4 HYDROXYTHREONINE 4 PHOSPHATE DEHYDROGENASE; ASPARTIC ACID; HISTIDINE; ISOCITRATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXIDOREDUCTASE; PHOSPHOTHREONINE; PROTEIN PDXA; PYRIDOXAL 5 PHOSPHATE; UNCLASSIFIED DRUG; ZINC;

ARTICLE; BIOSYNTHESIS; DECARBOXYLATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN FOLDING;

AMINO ACID SEQUENCE; BINDING SITES; CATIONS; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; IONS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NADP; OXIDATION-REDUCTION; OXIDOREDUCTASES; OXYGEN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PYRIDOXAL PHOSPHATE; SEQUENCE HOMOLOGY, AMINO ACID; ZINC;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0242353212     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M306344200     Document Type: Article

References (36)

1. Bilski, P., Li, M. Y., Ehrenshaft, M., Daub, M. E., and Chignell, C. F. (2000) Photochem. Photobiol. 71, 129-134
2. Ehrenshaft, M., Bilski, P., Li, M. Y., Chignell, C. F., and Daub, M. E. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 9374-9378
3. Hill, R. E., and Spenser, I. D. (1996) in Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology (Neidhardt, F. C., Curtiss, R., III, Ingraham, J. L., Lin, E. C. C., Low, K. B., Magasanik, B., Reznikoff, W. S., Riley, M., Schaechter, M., and Umbarger, H. E., eds) pp. 695-703, ASM Press, Washington, D. C.
4. Ehrenshaft, M., Chung, K. R., Jenns, A. E., and Daub, M. E. (1999) Curr. Genet. 34, 478-485
5. Yang, Y., Zhao, G., Man, T. K., and Winkler, M. E. (1998) J. Bacteriol. 180, 4294-4299
6. Laber, B., Maurer, W., Scharf, S., Stepusin, K., and Schmidt, F. S. (1999) FEBS Lett. 449, 45-48
7. Mittenhuber, G. (2001) J. Mol. Microbiol. Biotechnol. 3, 1-20
8. Cane, D. E., Hsiung, Y., Cornish, J. A., Robinson, J. K., and Spenser, I. D. (1998) J. Am. Chem. Soc. 120, 1936-1937
9. Cane, D. E., Du, S., Robinson, J. K., Hsiung, Y., and Spenser, I. D. (1999) J. Am. Chem. Soc. 121, 7722-7723
10. Cane, D. E., Du, S., and Spenser, I., D. (2001) J. Am. Chem. Soc. 122, 4213-4214
11. Marcus, J. P., and Dekker, E. E. (1993) J. Bacteriol. 175, 6505-6511
12. Marcus, J. P., and Dekker, E. E. (1993) Biochem. Biophys. Res. Commun. 190, 1066-1072
13. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J. (1997) Nucleic Acids Res. 25, 3389-3402
14. Grissom, C. B., and Cleland, W. W. (1988) Biochemistry 27, 2934-2943
15. Franco, M. G., Laber, B., Huber, R., and Clausen, T. (2001) Structure (Camb.) 9, 245-253
16. Garrido-Franco, M., Ehlert, S., Messerschmidt, A., Marinkovic, S., Huber, R., Laber, B., Bourenkov, G. P., and Clausen, T. (2002) J. Biol. Chem. 277, 12396-12405
17. Yeh, J. I., Du, S., Pohl, E., and Cane, D. E. (2002) Biochemistry 41, 11649-11657
18. Hendrickson, W. A., Horton, J. R., and LeMaster, D. M. (1990) EMBO J. 9, 1665-1672
19. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
20. Terwilliger, T. C., and Berendzen, J. (1999) Acta Crystallogr. Sect. D Biol. Crystallogr. 55, 849-861
21. Terwilliger, T. C. (2001) Acta Crystallogr. D Biol. Crystallogr. 57, 1763-1775
22. Jones, T. A., Zhou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. Sect. A 47, 110-119
23. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr, Sect. D Biol. Crystallogr. 54, 905-921
24. Navaza, J. (1994) Acta Crystallogr. Sect. A 50, 157-163
25. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
26. Hurley, J. H., Dean, A. M., Sohl, J. L., Koshland, D. E., Jr., and Stroud, R. M. (1990) Science 249, 1012-1016
27. Imada, K., Sato, M., Tanaka, N., Katsube, Y., Matsuura, Y., and Oshima, T. (1991) J. Mol. Biol. 222, 725-738
28. Lo, C. L., Alley, B., Hubbard, T. J., Brenner, S. E., Murzin, A. G., and Chothia, C. (2000) Nucleic Acids Res. 28, 257-259
29. Holm, L., and Sander, C. (1997) Nucleic Acids Res. 25, 231-234
30. Guex, N., and Peitsch, M. C. (1997) Electrophoresis 18, 2714-2723
31. Doyle, S. A., Beernink, P. T., and Koshland, D. E., Jr. (2001) Biochemistry 40, 4234-4241
32. Mesecar, A. D., Stoddard, B. L., and Koshland, D. E., Jr. (1997) Science 277, 202-206
33. Imada, K., Inagaki, K., Matsunami, H., Kawaguchi, H., Tanaka, H., Tanaka, N., and Namba, K. (1998) Structure 6, 971-982
34. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950
35. Merritt, E. A., and Bacon, D. J. (1997) Methods Enzymol. 277, 505-524
36. Esnouf, R. M. (1999) Acta Crystallogr. D55, 938-940