The role of hepatocellular oxidative stress in Kupffer cell activation during 1,2-dichlorobenzene-induced hepatotoxicity

Toxicological Sciences

Volumn 76, Issue 1, 2003, Pages 201-211

  Younis, Husam S ^a   Parrish, Alan R ^b   Sipes, I Glenn ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

1,2 dichlorobenzine; Fischer 344 rat; Kupffer cell; Sprague Dawley rat

Indexed keywords

1,2 DICHLOROBENZENE; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ACTIVATION; CELL COMMUNICATION; CELL CULTURE; CELL STIMULATION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA BINDING; DNA RESPONSIVE ELEMENT; HYPOTHESIS; INCUBATION TIME; KUPFFER CELL; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; RAT STRAIN; SIGNAL TRANSDUCTION; TOXICITY TESTING; UPREGULATION;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CHLOROBENZENES; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE DISULFIDE; HEPATOCYTES; INSECTICIDES; KUPFFER CELLS; MALE; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN BINDING; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; RECEPTORS, INTERLEUKIN-8B; TIME FACTORS; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0242331698     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfg207     Document Type: Article

References (48)

1. Beyaert, R., and Fiers, W. (1994). Molecular mechanisms of tumor necrosis factor-induced cytotoxicity: What we do understand and what we do not. FEBS Lett. 340, 9-16.
2. Bone-Larson, C. L., Hogaboam, C. M, Evanhoff, H., Strieterm R. M., and Kunkel, S. L. (2001). IFN-gamma-inducible protein-10 (CXCL10) is hepato-protective during acute liver injury through the induction of CXCR2 on hepatocytes. J. Immunol. 167, 7077-7783.
3. Bowie, A., and O'Neill, L. A. (2000). Oxidative stress and nuclear factor-kappaB activation: A reassessment of the evidence in the light of recent discoveries. Biochem. Pharmacol. 59, 13-23.
4. Dambach, D. M., Watson, L. M., Gray, K. R., Durham, S. K., and Laskin, D. L. (2002). Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse. Hepatology 35,:1093-1103.
5. Decker, K. (1990). Biologically active products of stimulated liver macrophages (Kupffer cells). Eur. J. Biochem. 192, 245-261.
6. Dignam, J. D., Martin, P. L., Shastry, B. J., and Roeder, R. G. (1983). Eukaryotic gene transcription with purified components. Methods Enzymol. 101, 582-598.
7. Dong, W., Simeonova, P., Gallucci, R., Matheson, J., Flood, L., Wang, S., Hubbs, A., and Luster, M. I. (1998). Toxic metals stimulate inflammatory cytokines in hepatocytes through oxidative stress mechanisms. Toxicol. Appl. Pharmacol. 151, 359-366.
8. Fariss, M. W., and Reed, D. J. (1987). High-performance liquid chromatography of thiols and disulfides: dinitrophenol derivatives. Methods Enzymol. 143, 101-109.
9. Fujino, H., Pierce, K. L., Srinivasan, D., Protzman, C. E., Krauss, A. H., Woodward, D. F., and Regan, J. W. (2000). Delayed reversal of shape change in cells expressing FP(B) prostanoid receptors: Possible role of receptor resensitization. J. Biol. Chem. 275, 29907-29914.
10. 15N]nitrite in biological fluids. Anal. Biochem. 126, 131-138.
11. Gunawardhana, L., Mobley, S. A., and Sipes, I. G. (1993). Modulation of 1,2-dichlorobenzene hepatotoxicity in the Fischer-344 rat by a scavenger of superoxide anions and an inhibitor of Kupffer cells. Toxicol. Appl. Pharmacol. 119, 205-213.
12. Hibi, M., Lin, A., Smeal, T., Minden, A., and Karin, M. (1993). Identification of an oncoprotein and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7, 2135-2148.
13. Hissink, A., Oudshoorn, M., Van Ommen, B., Guido, R., Haenen, M., and Van Bladeren, P. (1996). Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: Implications for human risk assessment. Chem. Res. Toxicol. 9, 1249-1256.
14. Hoglen, N. C., Younis, H. S., Hartley, D. P., Gunawardhana, L., and Sipes, I. G. (1998). 1,2-Dichlorobenzene-induced lipid peroxidation in male Fischer-344 rats is Kupffer-cell dependent. Toxicol. Sci. 46, 376-385.
15. Horbach, M., Gerer, E., and Kahl, R. (1997). Influence of acetaminophen treatment and hydrogen peroxide treatment on the release of a CINC-related protein and TNF-α from rat hepatocyte cultures. Toxicology 121, 117-126.
16. Jaeschke, H., and Benzick, A. E. (1992). Pathological consequences of enhanced intracellular superoxide formation in isolated perfused rat liver. Chem.-Biol. Interact. 84, 55-68.
17. Karin, M., Takahashi, T., Kapahi, P., Delhase, M., Chen, Y., Makris, C., Rothwarf, D., Baud, V., Natoli, G., Guido, F., and Li, N. (2001) Oxidative stress and gene expression: The AP-1 and NF-κB connections. Biofactors 15, 87-89.
18. Kataoka, M., Shimizu, H., Mitsuhashi, N., Ohtsuka, M., Wakabayashi, Y., Ito, H., Kimura, F., Nakagawa, K., Yoshidome, H., Shimizu, Y., et al. (2002). Effect of cold-ischemia time on C-X-C chemokine expression and neutrophil accumulation in the graft liver after orthotopic liver transplantation in rats. Transplantation 73, 1730-1735.
19. Kuester, R. K., Waalkes, M. P., Goering, P. L., Fisher, B. L., McCuskey, R. S., and Sipes, I. G. (2002). Differential hepatotoxicity induced by cadmium in Fischer 344 and Sprague-Dawley rats. Toxicol. Sci. 65, 151-159.
20. Kulkarni, S. G., Harris, A. J., Casciano, D. A., and Mehendale, H. M. (1999). Differential protooncogene expression in Sprague-Dawley and Fischer-344 rats during 1,2-dichlorobenzene-induced hepatocellular regeneration. Toxicology 139, 119-127.
21. Kulkarni, S. G., Warbritton, A., Bucci, T. J., and Mehendale, H. M. (1997). Antimitotic intervention with colchicine alters the outcome of o-DCB-induced hepatotoxicity in Fischer 344 rats. Toxicology 120, 79-88.
22. 2 and tumor necrosis factor-α induce differential binding of the redox-responsive transcription factors AP-1 and NF-κB to the interleukin-8 promoter in endothelial and epithelial cells. J. Biol. Chem. 273, 32670-32678.
23. Laskin, D. L., and Pedino, K. J. (1995). Macrophages and inflammatory mediators in tissue injury. Annu. Rev. Pharmacol. Toxicol. 35, 655-677.
24. Laskin, D. L., Pilaro, A. M., and Ji, S. (1986). Potential role of activated macrophages in acetaminophen hepatotoxicity. Toxicol. Appl. Pharmacol. 86, 216-226.
25. Luckey, S. W., and Petersen, D. R. (2002). Activation of Kupffer cells during the course of carbon tetrachloride-induced liver injury and fibrosis in rats. Exp. Mol. Pathol. 71, 226-240.
26. Maher, J. J., Lozier, J. S., and Scott, M. K. (1998). Rat hepatic stellate cells produce cytokine-induced neutrophil chemoattractant in culture and in vivo. Am. J. Physiol. 275, G847-853.
27. McQueen, C. A., Rosado, R. R., and Williams, G. M. (1989). Effect of nalidixic acid on DNA repair in rat hepatocytes. Cell. Biol. Toxicol. 5, 201-206.
28. Mertens, J. J., Gibson, N. W., Lau, S. S., and Monks, T. J. (1995). Reactive oxygen species and DNA damage in 2-bromo-(glutathion-S-yl) hydroquinone-mediated cytotoxicity. Arch. Biochem. Biophys. 320, 51-58.
29. Monks, T. J., and Jones, D. C. (2002). The metabolism and toxicity of quinones, quinonimines, quinone methides, and quinone-thioethers. Curr. Drug. Metab. 3,:425-438.
30. 1 mice (gavage studies). U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health. NIH Publication No. 86, 2511. Research Triangle Park, NC.
31. Ohtsuka, T., Kubota, A., Hirano, T., Watanabe, K., Yoshida, H., Tsurufuji, M., Lizuka, Y., Konishi, K., and Tsurufuji, S. (1996). Glucocorticoid-mediated gene suppression of rat cytokine-induced neutrophil chemoattractanct CINC/gro, a member of the interleukin-8 family, through impairment of NF-κB activation. J. Biol. Chem. 71, 1651-1659.
32. Okada, K., Marubayashi, S., Fukuma, K., Yamada, K., and Dohi, K. (2000). Effect of the 21-aminosteroid on nuclear factor-kappa B activation of Kupffer cells in endotoxin shock. Surgery. 127, 79-86.
33. Petering. H., Gotze, O., Kimmig, D., Smolarski, R., Kapp, A., and Elsner, J. (1999). The biologic role of interleukin-8: Functional analysis and expression of CXCR1 and CXCR2 on human eosinophils. Blood 93, 694-702.
34. Ren, X., Kennedy, A., and Colletti, L. M. (2002). Cxc chemokine expression after stimulation with interferon-gamma in primary rat hepatocytes in culture. Shock. 6,:513-520.
35. Saccani, A., Saccani, S., Orlando, S., Sironi, M., Bernasconi, S., Ghezzi, P., Mantovani, A., and Sica, A. (2000). Redox regulation of chemokine receptor expression. PNAS 97, 2761-2766.
36. Sauer, J. M., Waalkes, M. P., Hooser, S. B., Kuester, R. K., McQueen, C. A., and Sipes, I. G. (1997). Suppression of Kupffer-cell function prevents cadmium-induced hepatocellular necrosis in the male Sprague-Dawley rat. Toxicology 121, 155-164.
37. Sipes, I. G., Elsisi, A. E., Sim, W., Mobley, S., and Earnest, D. (1989). Role of reactive oxygen species secreted by activated Kupffer cells in the potentiation of carbon tetrachloride hepatotoxicity by hypervitaminos A. In Cells of the Hepatic Sinusoid (E. Wisse, D. Knock, and K. Decker, Eds.), pp. 2, 376-379. Elsevier Biomedical Press, New York.
38. Soni, M. G., Ramaiah, S. K., Mumtaz, M. M., Clewell, H., and Mehendale, H. M. (1999). Toxicant-inflicted injury and stimulated tissue repair are opposing toxicodynamic forces in predictive toxicology. Regul. Toxicol. Pharmacol. 29(2, Pt 1), 165-174.
39. Spitzer, J. A., and Zhang, P. (1996). Gender differences in phagocytic response in the blood and liver, and the generation of cytokine-induced neutrophil chemoattractant in the liver of acutely ethanol-intoxicated rats. Alcohol. Clin. Exp. Res. 20, 914-920.
40. Stamer, W., Snyder, R., Smith, B., Agre, P., and Regan, J. (1994). Localization of aquaporin chip in the human eye: Implications in the pathogenesis of glaucoma and other disorders of ocular fluid balance. Investig. Ophthalmol. Vis. Sci. 35, 3867-3872.
41. Stine, E., Gunawardhana, L., and Sipes, I. G. (1991). The acute hepatotoxicity of the isomers of dichlorobenzene in Fisher-344 and Sprague-Dawley rats: Isomer-specific and strain-specific differential toxicity. Toxicol. Appl. Pharmacol. 109, 472-481.
42. Swope, M. D., and Lolis, E. (1999). Macrophage migration inhibitory factor: Cytokine, hormone, or enzyme? Rev. Physiol. Biochem. Pharmacol. 139, 1-32.
43. Thornton, A. J., Ham, J., and Kunkel, S. L. (1992). Kupffer cell-derived cytokines induce the synthesis of a leukocyte chemotactic peptide, interleukin-8, in human hepatoma and primary hepatocyte cultures. Hepatology 15, 1112-1122.
44. Tran-Thi, T. A., Decker, K., and Baeuerle, P. A. (1995). Differential activation of transcription factors NF-κB and AP-1 in rat liver macrophages. Hepatology 22, 613-619.
45. Tsukamoto, H., Lin, M., Ohata, M., Giulivi, C., French, S. W., and Brittenham, G. (1999). Iron primes hepatic macrophages for NF-κB activation in alcoholic liver injury. Am. J. Physiol. 277(6, Pt.1), G1240-1250.
46. Wilkinson, J., and Clapper, M. L. (1997). Detoxification enzymes and chemoprevention. Proc. Soc. Exp. Bio. Med. 216, 192-200.
47. Yamada, S., Matsuoka, H., Harada, Y., Momosaka, Y., Isumi, H., Kohno, K., Yamaguchi, Y., and Eto, S. (1999). Effect of long-term ethanol consumption on ability to produce cytokine-induced neutrophil chemattractant-1 in the rat liver and its gender difference. Alcohol. Clin. Exp. Res. 23(Suppl. 4), 61-66S.
48. Younis, H. S., Hoglen, N. C., Kuester, R. K., Gunawardhana, L., and Sipes, I. G. (2000). 1,2-Dichlorobenzene-mediated hepatocellular oxidative stress in Fischer-344 and Sprague-Dawley rats. Toxicol. Appl. Pharmacol. 163, 141-148.