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Volumn 125, Issue 44, 2003, Pages 13541-13547

Real-Time Multicolor DNA Detection with Chemoresponsive Diffraction Gratings and Nanoparticle Probes

Author keywords

[No Author keywords available]

Indexed keywords

SIGNAL TRANSDUCTION;

EID: 0242267568     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja035479k     Document Type: Article
Times cited : (144)

References (35)
  • 18
    • 0242273228 scopus 로고    scopus 로고
    • note
    • Caution! Pirahna solutions are extraordinarily dangerous, reacting explosively with trace quantities of organics.
  • 19
    • 0242369923 scopus 로고    scopus 로고
    • note
    • In contrast to SPR measurements, small differences in angle of incidence are of little consequence for grating efficiency measurements.
  • 20
    • 0242275198 scopus 로고    scopus 로고
    • note
    • Though it is clear from Figure 3a that the observed signal is highly nonlinear over the full dynamic range of the sensor, for reasons detailed in the Discussion section, the response should be linear for extrapolation in the low concentration range.
  • 21
    • 0242307009 scopus 로고    scopus 로고
    • note
    • HIV-1 isolate 97ZM057F from Zambia nonfunctional envelope glycoprotein (env) gene (AF405180, b., N166-198th). Detailed information is available on the National Center fro Biotechnology Information (NCBI) website: http://www2.ncbi.nlm.nih.gov/Genbank/index.html.
  • 22
    • 0242275197 scopus 로고    scopus 로고
    • note
    • According to eq 3, assuming constant grating thickness.
  • 23
    • 0242338550 scopus 로고    scopus 로고
    • note
    • [α = 2,3·OD(λ)/t] and [ω = 2πc/λ], where c is the speed of light, λ is the wavelength of light, OD(λ) is the optical density of the grating, and t is the grating thickness.
  • 24
    • 0242338572 scopus 로고    scopus 로고
    • note
    • Mere proximity of the bound particles to the gold platform, however, should also alter the particles' plasmon absorption to a small extent. For simplicity, and because we lack quantitative information about the anticipated alteration, we neglect this effect in the discussion that follows.
  • 27
    • 0242307047 scopus 로고    scopus 로고
    • note
    • Experimental extinction spectra for surface and solution aggregates of gold nanoparticles generally feature significant scattering components in addition light absorption. Equation 3, on the other hand, employs only the absorption component.
  • 28
    • 0242338571 scopus 로고    scopus 로고
    • note
    • (632nm) = 0.1797.
  • 29
    • 0242275199 scopus 로고    scopus 로고
    • note
    • The index contrast of the grating, prior to hybridization, also contains a contribution from the attached ssDNA; however, the contribution is small in an effective medium context (see ref 9), so is neglected in calculations here.
  • 30
    • 0242307008 scopus 로고    scopus 로고
    • note
    • Recall that DE is defined here as a ratio of diffracted-to-undiffracted light intensities; both are attenuated by solution absorption but to precisely proportional extents.
  • 35
    • 0037023086 scopus 로고    scopus 로고
    • Recently a two-wavelength SPR experiment has been reported, though not utilizing probe label absorptions for signal magnitude enhancement purposes: Zacher, T.; Wischerhoff, E. Langmuir 2002, 18, 1748-1759.
    • (2002) Langmuir , vol.18 , pp. 1748-1759
    • Zacher, T.1    Wischerhoff, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.