The androgen receptor transactivation domain: The interplay between protein conformation and protein-protein interactions

Biochemical Society Transactions

Volumn 31, Issue 5, 2003, Pages 1042-1046

  Reid, J ^a,b   Betney, R ^a   Watt, K ^a   McEwan, I J ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Fluorescence spectroscopy; Mutagenesis; Secondary structure prediction; Steroid receptor; Transactivation

Indexed keywords

ANDROGEN RECEPTOR; DNA; PROTEINASE; SOLVENT; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TFIIF; TRIFLUOROETHANOL; TRIMETHYLAMINE OXIDE; TRYPTOPHAN; UNCLASSIFIED DRUG;

CONFERENCE PAPER; DNA BINDING; ENVIRONMENTAL EXPOSURE; HORMONE BINDING; HUMAN; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TARGETING; STRUCTURE ANALYSIS; TRANSACTIVATION; TRANSCRIPTION INITIATION;

EID: 0142217034     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/bst0311042     Document Type: Conference Paper

References (27)

1. Gelman, E.P. (2002) J. Clin. Oncol. 20, 3001-3015
2. Matia, P.D., Donner, P., Coelho, R., Thomaz, M., Peixoto, C., Macedo, S., Otto, N., Joschko, S., Scholz, P., Wegg, A. et al. (2000) J. Biol. Chem. 275, 26164-26171
3. Davies, T.H., Ning, Y.-M. and Sanchez, E.R. (2002) J. Biol. Chem. 277, 4597-4600
4. Kaul, S., Murphy, P.J.M., Chen, J., Brown, L., Pratt, W.B. and Stoney Simons, S. (2002) J. Biol. Chem. 277, 36223-36232
5. McEwan, I.J. (2001) Trends Genet. 17, 239-243
6. Verrijdt, G., Haelens, A. and Claessens, F. (2003) Mol. Gen. Metab. 78, 175-185
7. Zilliacus, J., Wright, A.P.H., Carlstedt-Duke, J. and Gustafsson, J.-Å. (1995) Mol. Endocrinol. 19, 389-400
8. Nelson, C.C., Hendy, S.C., Shukin, R.J., Cheng, H., Bruchovsky, N., Koop, B.F. and Rennie, P.S. (1999) Mol. Endocrinol. 13, 2090-2107
9. Simental, J.A., Sar, M., Lane, M.V., French, F.S. and Wilson, E.M. (1991) J. Biol. Chem. 266, 510-518
10. Jenster, G., van der Korput, H.A., Trapman, J. and Brinkmann, A.O. (1995) J. Biol. Chem. 270, 7341-7346
11. Chamberlain, N.L., Whitacre, D.C. and Miesfeld, R.L. (1996) J. Biol. Chem. 271, 26772-26778
12. He, B. and Wislon, E.M. (2002) Mol. Gen. Metab. 75, 293-298
13. Steketee, K., Berrevoets, C.A., Dubbink, H.J., Doesburg, P., Hersmus, R., Brinkmann, A.O. and Trapman, J. (2002) Eur. J. Biochem. 269, 5780-5791
14. Reid, J., Murray, I., Watt, K., Betney, R. and McEwan, I.J. (2002) J. Biol. Chem. 277, 41247-41253
15. McEwan, I.J. and Gustafsson, J.-Å. (1997) Proc. Natl, Acad. Sci. U.S.A. 94, 8485-8490
16. Alen, P., Claessens, F., Verhoeven, G., Rombauts, W. and Peeters, B. (1999) Mol. Cell. Biol. 19, 6085-6097
17. Ma, H., Hong, H., Huang, S.M., Irvine, R.A., Webb, P., Kushner, P.J., Coetzee, G.A. and Stallcup, M.R. (1999) Mol. Cell. Biol. 19, 6164-6173
18. Bevan, C.L., Hoare, S., Claessens, F., Heery, D.M. and Parker, M.G. (1999) Mol. Cell. Biol. 19, 8383-8392
19. 18a Betney, R. and McEwan, I.J. (2003) J. Mol. Endocrinol., in the press
20. Reid, J., Kelly, S.M., Watt, K., Price, N.C. and McEwan, I.J. (2002) J. Biol. Chem. 277, 20079-20086
21. Dahlman-Wright, K., Baumann, H., McEwan, I.J., Almlöf, T., Wright, A.P., Gustafsson, J.-Å. and Härd, T. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 1699-1703
22. Baskakov, I.V., Kumar, R., Srinivasan, G., Ji, Y.S., Bolen, D.W. and Thompson, E.B. (1999) J. Biol. Chem. 274, 10693-10696
23. Wärnmark, A., Wikström, A., Wright, A.P.H., Gustafsson, J.-Å. and Härd, T. (2001) J. Biol. Chem. 276, 45939-45944
24. Hi, R., Osada, S., Yumoto, N. and Osumi, T. (1999) J. Biol. Chem. 274, 35152-35158
25. Wright, P.E. and Dyson, H.J. (1999) J. Mol. Biol. 293, 321-331
26. Kumar, R., Lee, J.C. and Thompson, E.B. (2001) J. Biol. Chem. 276, 18146-18152
27. Combet, C., Blanchet, C., Geourjon, C. and Deleage, G. (2000) Trends Biochem. 25, 147-150