Identification and Characterization of Two Isoenzymes of Methionine γ-Lyase from Entamoeba histolytica: A key enzyme of sulfur-amino acid degradation in an anaerobic parasitic protist that lacks forward and reverse trans-sulfuration pathways

Journal of Biological Chemistry

Volumn 278, Issue 43, 2003, Pages 42717-42727

  Tokoro, Masaharu ^a   Asai, Takashi ^a   Kobayashi, Seiki ^a   Takeuchi, Tsutomu ^a   Nozaki, Tomoyoshi ^b,c,d  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d NONE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; GENES; HYDROGEN SULFIDE; METABOLISM; SUBSTRATES;

CELL FUNCTIONS;

ENZYMES;

2 OXOACID; AMINO ACID; AMMONIA; CYSTATHIONINE; CYSTEINE; ENZYME INHIBITOR; HOMOCYSTEINE; HYDROGEN SULFIDE; ISOENZYME; METHANETHIOL; METHIONINE; METHIONINE DERIVATIVE; METHIONINE GAMMA LYASE; METHIONINE GAMMA LYASE 1; METHIONINE GAMMA LYASE 2; O ACETYLSERINE; POLYPEPTIDE; PROPARGYLGLYCINE; SERINE DERIVATIVE; SULFUR AMINO ACID; TRIFLUOROMETHIONINE; UNCLASSIFIED DRUG;

AMEBIASIS; AMINO ACID METABOLISM; AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CATALYST; CYTOSOL; ENTAMOEBA HISTOLYTICA; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; IC 50; IMMUNOBLOTTING; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PREDICTION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TROPHOZOITE;

AMINO ACIDS, SULFUR; ANIMALS; BASE SEQUENCE; CARBON-SULFUR LYASES; CATALYSIS; CYTOSOL; ENTAMOEBA HISTOLYTICA; HYDROGEN-ION CONCENTRATION; ISOENZYMES; METHIONINE; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN STRUCTURE, QUATERNARY; PROTOZOAN PROTEINS; SUBSTRATE SPECIFICITY;

ARCHAEA; ENTAMOEBA; ENTAMOEBA HISTOLYTICA; PROTISTA; PROTOZOA; TRICHOMONAS VAGINALIS;

EID: 0142180049     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212414200     Document Type: Article

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