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Volumn 45, Issue 6, 2001, Pages 1743-1745

Trifluoromethionine, a prodrug designed against methionine γ-lyase-containing pathogens, has efficacy in vitro and in vivo against Trichomonas vaginalis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; METHIONINE GAMMA LYASE; PRODRUG; TRIFLUOROMETHIONINE; UNCLASSIFIED DRUG;

EID: 0034999373     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.6.1743-1745.2001     Document Type: Article
Times cited : (62)

References (12)
  • 1
    • 0020533978 scopus 로고
    • Conversion of trifluoromethionine to a cross linking agent by γ-cystathionase
    • Alston, T. A., and H. J. Bright. 1983. Conversion of trifluoromethionine to a cross linking agent by γ-cystathionase. Biochem. Pharmacol. 32:947-950.
    • (1983) Biochem. Pharmacol. , vol.32 , pp. 947-950
    • Alston, T.A.1    Bright, H.J.2
  • 3
    • 0029834843 scopus 로고    scopus 로고
    • Present status of therapy for anaerobic infections
    • Finegold, S. M., and H. M. Wexler. 1996. Present status of therapy for anaerobic infections. Clin. Infect. Dis. 23(Suppl. 1):S9-S14.
    • (1996) Clin. Infect. Dis. , vol.23 , Issue.1 SUPPL.
    • Finegold, S.M.1    Wexler, H.M.2
  • 4
    • 0030703162 scopus 로고    scopus 로고
    • Metronidazole - A therapeutic review and update
    • Freeman, C. D., N. E. Klutman, and K. C. Lamp. 1997. Metronidazole - a therapeutic review and update. Drugs 54:679-708.
    • (1997) Drugs , vol.54 , pp. 679-708
    • Freeman, C.D.1    Klutman, N.E.2    Lamp, K.C.3
  • 5
    • 0025947233 scopus 로고
    • Purification and characterisation of methionine γ-lyase from Trichomonas vaginalis
    • Lockwood, B. C., and G. H. Coombs. 1991. Purification and characterisation of methionine γ-lyase from Trichomonas vaginalis. Biochem. J. 279:675-682.
    • (1991) Biochem. J. , vol.279 , pp. 675-682
    • Lockwood, B.C.1    Coombs, G.H.2
  • 6
    • 0032489551 scopus 로고    scopus 로고
    • The primitive protozoon Trichomonas vaginalis contains two methionine-γ-lyase genes that encode members of the γ-family of pyridoxal-5′-phosphate-dependent enzymes
    • McKie, A. E., T. Edlind, J. Walker, J. C. Mottram, and G. H. Coombs. 1998. The primitive protozoon Trichomonas vaginalis contains two methionine-γ-lyase genes that encode members of the γ-family of pyridoxal-5′-phosphate-dependent enzymes. J. Biol. Chem. 273:5549-5556.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5549-5556
    • McKie, A.E.1    Edlind, T.2    Walker, J.3    Mottram, J.C.4    Coombs, G.H.5
  • 7
    • 0024416959 scopus 로고
    • Methionine recycling as a target for antiprotozoal drug development
    • Riscoe, M. K., A. J. Ferro, and J. H. Fitchen. 1989. Methionine recycling as a target for antiprotozoal drug development. Parasitol. Today 5:330-333.
    • (1989) Parasitol. Today , vol.5 , pp. 330-333
    • Riscoe, M.K.1    Ferro, A.J.2    Fitchen, J.H.3
  • 8
    • 0023066723 scopus 로고
    • Microbial sulphur amino acids - An overview
    • Soda, K. 1987. Microbial sulphur amino acids - an overview. Methods Enzymol. 143:453-459.
    • (1987) Methods Enzymol. , vol.143 , pp. 453-459
    • Soda, K.1
  • 10
    • 0023090703 scopus 로고
    • The effects of inhibitors of sulphur-containing amino acid metabolism on the growth of Trichomonas vaginalis in vitro
    • Thong, K.-W., and G. H. Coombs. 1987. The effects of inhibitors of sulphur-containing amino acid metabolism on the growth of Trichomonas vaginalis in vitro. J. Antimicrob. Chemother. 19:429-437.
    • (1987) J. Antimicrob. Chemother. , vol.19 , pp. 429-437
    • Thong, K.-W.1    Coombs, G.H.2
  • 11
    • 0023190215 scopus 로고
    • Trichomonas species: Homocysteine desulphurase and serine sulphydrase activities
    • Thong, K-W., and G. H. Coombs. 1987. Trichomonas species: homocysteine desulphurase and serine sulphydrase activities. Exp. Parasitol. 63:143-151.
    • (1987) Exp. Parasitol. , vol.63 , pp. 143-151
    • Thong, K.-W.1    Coombs, G.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.