Soluble Fas (CD95/Apo-1), Soluble Fas Ligand, and Activated Caspase 3 in the Cerebrospinal Fluid of Infants with Posthemorrhagic and Nonhemorrhagic Hydrocephalus

Pediatric Research

Volumn 54, Issue 5, 2003, Pages 659-664

  Felderhoff Mueser, Ursula ^a   Bührer, Christoph ^a   Groneck, Peter ^b   Obladen, Michael ^a   Bartmann, Peter ^c   Heep, Axel ^c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^c UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; FAS ANTIGEN; FAS LIGAND;

ARTICLE; BRAIN HEMORRHAGE; BRAIN VENTRICLE DILATATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GLIOSIS; HUMAN; HYDROCEPHALUS; LEUKOMALACIA; LUMBAR PUNCTURE; MALE; MENINGITIS; NERVE CELL DEGENERATION; NERVE FIBER DEGENERATION; NEWBORN; PREMATURITY; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; SHUNTING;

ANTIGENS, CD95; APOPTOSIS; CASPASE 3; CASPASES; FAS LIGAND PROTEIN; HUMANS; HYDROCEPHALUS; INFANT, NEWBORN; INFANT, PREMATURE; INTRACRANIAL HEMORRHAGES; LEUKOMALACIA, PERIVENTRICULAR; MALE; MEMBRANE GLYCOPROTEINS; SPINAL PUNCTURE;

EID: 0142179084     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/01.PDR.0000084114.83724.65     Document Type: Article

References (43)

1. Volpe JJ 2001 Intracranial hemorrhage: germinal matrix-intraventricular hemorrhage of the premature infant. In: Volpe JJ (ed) Neurology of the Newborn. 4th ed. Saunders, Philadelphia, pp 428-493
2. Fukumizu M, Takashima S, Becker LE 1995 Neonatal posthemorrhagic hydrocephalus: neuropathologic and immunohistochemical studies. Pediatr Neurol 13:230-234
3. Harris NG, Jones HC, Patel S 1994 Ventricle shunting in young HTX rats with inherited congenital hydrocephalus: a quantitative histological study of cortical grey matter. Childs Nerv Syst 10:293-301
4. Gopinath G, Bhatia R, Gopinath PG 1979 Ultrastructural observations in experimental hydrocephalus in the rabbit. J Neurol Sci 43:333-334
5. a. Miyan JA, Khan MI, Kawarada Y, Sugiyama T, Bannister CM 1998 Cell death in the brain of the HTx rat. Eur J Pediatr Surg Suppl 1:43-48
6. , Del Bigio MR, Zhang YW 1998 Cell death, axonal damage, and cell birth in the immature rat brain following induction of hydrocephalus. Exp Neurol 154:157-169
7. Dowling P, Shang G, Sumul R, Menonna J, Cook S, Husar W 1996 Involvement of the CD95 (APO-1/Fas) receptor/ligand system in the multiple sclerosis brain. J Exp Med 184:1513-1518
8. D'Souza S, Bonetti B, Balasingam V, Cashman N, Barker P, Troutt A, Raine C, Antel J 1996 Multiple sclerosis: Fas signaling in oligodendrocyte cell death. J Exp Med 184:2362-2370
9. Beer R, Franz G, Schopf M, Reindl M, Zelger B, Schmutzhard E, Poewe W, Kampfl A 2000 Expression of Fas and Fas ligand after experimental traumatic brain injury in the rat. J Cereb Blood Flow Metab 20:669-677
10. Felderhoff-Mueser U, Taylor DL, Greenwood K, Kozma M, Stibenz D, Joashi UC, Edwards AD, Mehmet H 2000 Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxicischemic injury to the developing rat brain. Brain Pathol 10:17-29
11. Nagata S, Golstein P 1995 The Fas death factor. Science 267:1449-1456
12. Bechmann I, Mor G, Nilsen J, Eliza M, Nitsch R, Naftolin F 1999 FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: evidence for the existence of an immunological brain barrier. Glia 27:62-74
13. Ju ST, Panka DJ, Cui H 1995 FasL interactions required for programmed cell death after T cell activation. Nature 373:444-448
14. Cascino I, Fiucci G, Papoff G, Ruberti 1995 Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing. J Immunol 154:2706-2713
15. Cheng J, Zhou T, Liu C, Shapiro JP, Brauer MJ, Kiefer MC, Barr PJ, Mountz JD 1994 Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science 263:1759-1762
16. Hughes DP, Crispe IN 1995 A naturally occurring soluble isoform of murine Fas generated by alternative splicing. J Exp Med 182:1395-1401
17. Tanaka M, Itai T, Adachi M, Nagata S 1998 Downregulation of Fas ligand by shedding. Nat Med 1:31-36
18. Porter AG, Janicke RU 1999 Emerging roles of caspase-3 in apoptosis. Cell Death Differ 6:99-104
19. Springer JE, Nottingham SA, McEwen ML, Azbill RD, Jin Y 2001 Caspase-3 apoptotic signaling following injury to the central nervous system. Clin Chem Lab Med 39:299-307
20. Hentze H, Schwoebel F, Lund S, Keel M, Ertel W, Wendel A, Jaattela M, Leist M, Kehl M 2001 In vivo and in vitro evidence for extracellular caspase activity released from apoptotic cells. Biochem Biophys Res Commun 283:1111-1117
21. Levene MI 1981 Measurement of the growth of the lateral ventricles in preterm infants with real-time ultrasound. Arch Dis Child 56:900-904
22. Heep A, Engelskirchen R, Holschneider A, Groneck P 2001 Primary intervention for posthemorrhagic hydrocephalus in very low birthweight infants by ventriculostomy. Childs Nerv Syst 17:47-51
23. Heep A, Stoffel-Wagner B, Soditt V, Aring C, Groneck P, Bartmann P 2002 Procollagen I C-propeptide in the cerebrospinal fluid of neonates with posthemorrhagic hydrocephalus. Arch Dis Child Fetal Neonatal Ed 87:F34-F36
24. Felderhoff-Mueser U, Sifringer M, Pesditschek S, Kuckuck H, Moysich A, Bittigau P, Ikonomidou C 2002 Pathways leading to apoptotic neurodegeneration following trauma to the developing rat brain. Neurobiol Dis 11:231-245
25. Nakashima K, Yamashita K, Uesugi S, Ito H 1999 Temporal and spatial profile of apoptotic cell death in transient intracerebral mass lesion of the rat. J Neurotrauma 16:143-151
26. van Landeghem FK, Felderhoff-Mueser U, Moysich A, Stadelmann C, Obladen M, Bruck W, Buhrer C 2002 Fas (CD95/Apo-1)/Fas ligand expression in neonates with pontosubicular neuron necrosis. Pediatr Res 51:129-135
27. Tullberg M, Rosengren L, Blomsterwall E, Karlsson JE, Wikkelso C 1998 CSF neurofilament and glial fibrillary acidic protein in normal pressure hydrocephalus. Neurology 50:1122-1127
28. Yang JT, Chang CN, Hsu YH, Wei KC, Lin TK, Wu JH 1999 Increase in CSF NGF concentration is positively correlated with poor prognosis of postoperative hydrocephalic patients. Clin Biochem 32:673-675
29. Hochhaus F, Koehne P, Schaper C, Butenandt O, Felderhoff-Mueser U, Ring-Mrozik E, Obladen M, Buhrer C 2001 Elevated nerve growth factor and neurotrophin-3 levels in cerebrospinal fluid of children with hydrocephalus. BMC Pediatr e1:2
30. Lenzlinger PM, Marx A, Trentz O, Kossmann T, Morganti-Kossmann MC 2002 Prolonged intrathecal release of soluble Fas following severe traumatic brain injury in humans. J Neuroimmunol 122:167-174
31. Sabri F, De Milito A, Pirskanen R, Elovaara I, Hagberg L, Cinque P, Price R, Chiodi F 2001 Elevated levels of soluble Fas and Fas ligand in cerebrospinal fluid of patients with AIDS dementia complex. J Neuroimmunol 114:197-206
32. Tarkowski E, Rosengren L, Blomstrand C, Jensen C, Ekholm S. Tarkowski A 1999 Intrathecal expression of proteins regulating apoptosis in acute stroke. Stroke 30:321-327
33. Ciusani E, Frigerio S, Gelati M, Corsini E, Dufour A, Nespolo A, La Mantia L, Milanese C, Massa G, Salmaggi A 1998 Soluble Fas (Apo-1) levels in cerebrospinal fluid of multiple sclerosis patients. J Neuroimmunol 82:5-12
34. Mogi M, Harada M, Kondo T, Mizuno Y, Narabayashi H, Riederer P, Nagatsu T 1996 The soluble form of Fas molecule is elevated in parkinsonian brain tissues. Neurosci Lett 220:195-198
35. Felderhoff-Mueser U, Herold R, Hochhaus F, Koehne P, Ring-Mrozik E, Obladen M, Buhrer C 2001 Increased cerebrospinal fluid concentrations of soluble Fas (CD95/Apo-1) in hydrocephalus. Arch Dis Child 84:369-372
36. Matsuki Y, Li L, Hsu HC, Yang PA, Zheng R, Edwards 3rd CK, Chaudry IH, Zhang HG, Mountz JD 2002 Soluble Fas gene therapy protects against Fas-mediated apoptosis of hepatocytes but not the lethal effects of Fas-induced TNF-alpha production by Kupffer cells. Cell Death Differ 9:626-635
37. Kayagaki N, Kawasaki A, Ebata T, Ohmoto H, Ikeda S, Inoue S, Yoshino K, Okumura K, Yagita H 1995 Metalloproteinase-mediated release of human Fas ligand. J Exp Med 182:1777-1783
38. Ertel W, Keel M, Stocker R, Imhof HG, Leist M, Steckholzer U, Tanaka M, Trentz O, Nagata S 1997 Detectable concentrations of Fas ligand in cerebrospinal fluid after severe head injury. J Neuroimmunol 80:93-96
39. Bittigau P, Sifringer M, Pohl D, Stadthaus D, Ishimaru M, Shimizu H, Ikeda M, Lang D, Speer A, Olney JW, Ikonomidou C 1999 Apoptotic neurodegeneration following trauma is markedly enhanced in the immature brain. Ann Neurol 45:724-735
40. Harter L, Keel M, Hentze H, Leist M, Ertel W 2001 Caspase-3 activity is present in cerebrospinal fluid from patients with traumatic brain injury. J Neuroimmunol 121:76-78
41. Choi C, Park JY, Lee J, Lim JH, Shin EC, Ahn YS, Kim CH, Kim SJ, Kim JD, Choi IS, Choi IH 1999 Fas ligand and Fas are expressed constitutively in human astrocytes and the expression increases with IL-1, IL-6, TNF-alpha, or IFN-gamma. J Immunol 162:1889-1895
42. Spanaus KS, Schlapbach R, Fontana A 1998 TNF-alpha and IFN-gamma render microglia sensitive to Fas ligand-induced apoptosis by induction of Fas expression and down-regulation of Bcl-2 and Bcl-xL. Eur J Immunol 28:4398-4408
43. Bechmann I, Lossau S, Steiner B, Mor G, Gimsa U, Nitsch R 2000 Reactive astrocytes upregulate Fas (CD95) and Fas ligand (CD95L) expression but do not undergo programmed cell death during the course of anterograde degeneration. Glia 32:25-41