GABAB receptor antagonist CGP-36742 enhances somatostatin release in the rat hippocampus in vivo and in vitro

European Journal of Pharmacology

Volumn 478, Issue 2-3, 2003, Pages 111-119

  Nyitrai, Gabriella ^a   Kékesi, Katalin A ^b   Emri, Zsuzsa ^a   Szárics, Éva ^a   Juhász, Gábor ^b   Kardos, Julianna ^a  

^a CHEMICAL RESEARCH CENTER   (Hungary)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

Author keywords

Brain; GABA ( aminobutyric acid); GABAB receptors; Glutamate; Hippocampus; Rat; Somatostatin

Indexed keywords

3 AMINOPROPYLBUTYLPHOSPHINIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; SOMATOSTATIN; SOMATOSTATIN RECEPTOR;

ANESTHESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CONCENTRATION RESPONSE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MALE; MASS SPECTROMETRY; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SOMATOSTATIN RELEASE;

EID: 0142169059     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2003.08.006     Document Type: Article

References (51)

1. Arancibia S., Payet O., Giavalois L., Tapia-Arancibia L. Acute stress and dexamethason rapidly increase hippocampal somatostatin synthesis and release from the dentate gyrus hilus. Hippocampus. 11:2001;469-477.
2. B antagonists: potential new drugs. Pharmacol. Commun. 2:1992;70-74.
3. Boehm S., Betz H. Somatostatin inhibits excitatory transmission at rat hippocampal synapses via presynaptic receptors. J. Neurosci. 17:1997;4066-4075.
4. B receptors. Trends Pharmacol. Sci. 14:1993;259-261.
5. B antagonist endowed with cognition enhancing activity. Neuropharmacology. 38:1999;1789-1795.
6. B receptor pharmacology. Annu. Rev. Pharmacol. Toxicol. 33:1993;109-147.
7. B receptors: first of the functional metabotropic heterodimers. J. Pharmacol. Exp. Ther. 292:2000;2-7.
8. B receptors: structure and function. Pharmacol. Rev. 54:2002;247-264.
9. Davies P., Katzmann R., Terry R.D. Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementia. Nature. 288:1980;279-280.
10. B receptors of neocortical neurons of the rat in vitro: differences in pharmacology and ionic mechanisms. Synapse. 25:1997;62-72.
11. Freund T.F., Buzsáki G. Interneurons of the hippocampus. Hippocampus. 6:1996;347-470.
12. B antagonists. Pharmacol. Commun. 2:1992;52-56.
13. B antagonists. J. Med. Chem. 38:1995;3313-3331.
14. Gardette R., Faivre-Bauman A., Loudes C., Kordon C., Epelbaum J. Modulation by somatostatin of glutamate sensitivity during development of mouse hypothalamic neurons in vitro. Brain Res. Dev. Brain Res. 86:1995;123-133.
15. Gemignani A., Paudice P., Bonanno G., Raiteri M. Pharmacological discrimination between γ-aminobutyric acid type B receptors regulating cholecystokinin and somatostatin release from rat neocortex synaptosomes. Mol. Pharmacol. 46:1994;558-562.
16. Grouselle D., Winsky-Sommerer R., David J.P., Delacourte A., Dournaud P., Epelbaum J. Loss of somatostatin-like immunoreactivity in the frontal cortex of Alzheimer patiens carrying the apolipoprotein epsilon 4 allele. Neurosci. Lett. 255:1998;21-24.
17. Hajós F. An improved method for the preparation of synaptosomal fractions in high purity. Brain Res. 93:1975;485-489.
18. Iversen L.L., Iversen S.D., Bloom F., Douglas C., Brown M., Vale W. Calcium-dependent release of somatostatin and neurotensin from rat brain in vitro. Nature. 273:1978;161-163.
19. Kaneko S., Maeda T., Satoh M. Cognitive enhancers and hippocampal long-term potentiation in vitro. Behav. Brain Res. 83:1997;45-49.
20. B receptor: the effect of CGP 55845A on the release of amino acids. Pharmacol. Rev. Commun. 8:1996;153-157.
21. B receptors uncovers similarity to metabotropic glutamate receptors. Nature. 386:1997;239-246.
22. B receptor heterogeneity. Pharmacol. Rev. Commun. 8:1996;163-165.
23. Koenig J.A., Kaur R., Dodgeon I., Edwardson J.M., Humprey P.P.A. Fates of endocytesed somatostatin SST2 receptors and associated agonists. Biochem. J. 336:1998;291-298.
24. Leresche N., Asprodini E., Emri Z., Cope D.W., Crunelli V. Somatostatin inhibits GABAergic transmission in the sensory thalamus via presynaptic receptors. Neuroscience. 98:2000;513-522.
25. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
26. B receptors - the first 7TM heterodimers. Trends Pharmacol. Sci. 20:1999;396-399.
27. Matsuoka N., Yamazaki M., Yamaguchi I. Changes in brain somatostatin in memory-deficient rats: comparison with cholinergic markers. Neuroscience. 66:1995;617-626.
28. 3H]GABA from slices of rat caudatoputamen. Neuroscience. 28:1989;61-68.
29. B blocker improves the cognitive performance of mice, rats, and rhesus monkeys. Behav. Neural Biol. 60:1993;62-68.
30. B receptor antagonist, facilitates memory in a social recognition test in rats. Behav. Brain Res. 77:1996;227-229.
31. Moore S.D., Madamba S.G., Joels M., Siggins G.R. Somatostatin augments the M-current in hippocampal neurons. Science. 239:1988;278-280.
32. Nakata A., Saito H., Nishiyama N. Facilitatory role of somatostatin via muscarinic cholinergic system in the generation of long-term potentiation in the rat dentate gyrus in vivo. Brain Res. 723:1996;135-140.
33. Nicholls D.G. Proteins, Transmitters and Synapses. 1994;Blackwell, Great Britain.
34. B receptors increases excitatory amino acid levels. Eur. J. Pharmacol. 318:1996;295-300.
35. Nyitrai G., Szárics É., Kovács I., Kékesi A.K., Juhász G., Kardos J. Effect of CGP 36742 on the extracellular level of neurotransmitter amino acids in the thalamus. Neurochem. Int. 34:1999;391-398.
36. B receptor antagonists on GABAergic transmission in vivo and in vitro. Eur. J. Pharmacol. 233:1993;179-186.
37. B presynaptic receptors in rat brain. Eur. J. Pharmacol. 415:2001;191-195.
38. Paxinos G., Watson C. The Rat Brain Stereotaxic Coordinates. 1997;Academic Press, Orlando.
39. B receptor antagonists. Neuropharmacology. 41:2001;301-310.
40. B receptors at inhibitory synapses in the CA1 region of the rat hippocampus. Br. J. Pharmacol. 127:1999;211-219.
41. Rocheville M., Lange D.C., Kumar U., Patel S.C., Patel R.C., Patel Y.C. Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity. Science. 288:2000;154-157.
42. Scharfman H.E., Schwartzkroin P.A. Selective depression of GABA-mediated IPSPs by somatostatin in area CA1 of rabbit hippocampal slices. Brain Res. 493:1989;205-211.
43. Selmer I.-S., Schindler M., Allen J.P., Humphrey P.P.A., Emson P.C. Advances in understanding neuronal somatostatin receptors. Regulatory Pept. 90:2000;1-18.
44. Sodickson D.L., Bean B.P. Neurotransmitter activation of inwardly rectifying potassium current in dissociated hippocampal CA3 neurons: interactions among multiple receptors. J. Neurosci. 18:1998;8153-8162.
45. Srikant C.B., Patel Y.C. Somatostatin receptors: identification and characterization in rat brain membranes. Proc. Natl. Acad. Sci. U. S. A. 78:1981;3930-3934.
46. Stroh T., Jackson A.C., Dal Farra C., Schonbrunn A., Vincent J.P., Beaudet A. Receptor-mediated internalization of somatostatin in rat cortical and hippocampal neurons. Synapse. 38:2000;177-186.
47. Tallent M.K., Siggins G.R. Somatostatin depresses excitatory but not inhibitory neurotransmission in rat CA1 hippocampus. J. Neurophysiol. 78:1997;3008-3018.
48. B antagonists. Br. J. Pharmacol. 118:1996;1153-1160.
49. B receptor antagonists with similar potency: no evidence for pharmacologically different presynaptic receptors. Br. J. Pharmacol. 113:1994;1515-1521.
50. B receptor. Nature. 396:1998;679-682.
51. Xie Z., Sastry B.R. Actions of somatostatin on GABA-ergic synaptic transmission in the CA1 area of the hippocampus. Brain Res. 591:1992;239-247.