Structural Evidence for a 1,2-Enediolate Intermediate in the Reaction Catalyzed by 3-Keto-L-Gulonate 6-Phosphate Decarboxylase, a Member of the Orotidine 5′-Monophosphate Decarboxylase Suprafamily

Biochemistry

Volumn 42, Issue 42, 2003, Pages 12133-12142

  Wise, Eric L ^a   Yew, Wen Shan ^b   Gerlt, John A ^b   Rayment, Ivan ^a,c  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c Department of Biochemistry ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CRYSTAL STRUCTURE; OXYGEN; SUBSTRATES;

DECARBOXYLATION;

ENZYMES;

3 KETOGULONATE 6 PHOSPHATE DECARBOXYLASE; ASPARTIC ACID; CARBON DIOXIDE; GULONATE 6 PHOSPHATE; LYSINE; MAGNESIUM ION; OROTIDINE 5' PHOSPHATE DECARBOXYLASE; PHOSPHATE; THREONOHYDROXAMATE 4 PHOSPHATE; UNCLASSIFIED DRUG; XYLITOL 5 PHOSPHATE; XYLULOSE; XYLULOSE 5 PHOSPHATE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CHEMICAL REACTION; DECARBOXYLATION; ENZYME ACTIVE SITE; GEOMETRY; HYDROGEN BOND; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN FAMILY; PROTON TRANSPORT;

CARBOXY-LYASES; CATALYSIS; CRYSTALLIZATION; ESCHERICHIA COLI PROTEINS; HYDROGEN BONDING; MODELS, MOLECULAR; OROTIDINE-5'-PHOSPHATE DECARBOXYLASE; OXYGEN; PROTEIN CONFORMATION;

EID: 0142126747     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0348819     Document Type: Article

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