Synthesis of a transition state analogue inhibitor of purine nucleoside phosphorylase via the Mannich reaction

Organic Letters

Volumn 5, Issue 20, 2003, Pages 3639-3640

  Evans, Gary B ^a   Furneaux, Richard H ^a   Tyler, Peter C ^a   Schramm, Vern L ^b  

^a CALLAGHAN INNOVATION   (New Zealand)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; ENZYME INHIBITOR; IMMUCILLIN G; IMMUCILLIN H; PURINE DERIVATIVE; PURINE NUCLEOSIDE PHOSPHORYLASE; PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITOR; PYRIMIDINONE DERIVATIVE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMISTRY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; MANNICH REACTION; PHASE TRANSITION; SYNTHESIS;

AMINES; ENZYME INHIBITORS; HUMANS; PURINE-NUCLEOSIDE PHOSPHORYLASE; PURINES; PYRIMIDINONES; PYRROLES;

EID: 0142106430     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol035293q     Document Type: Article

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