Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate

Biochemical Pharmacology

Volumn 66, Issue 4, 2003, Pages 643-652

  Pestel, Sabine ^a   Nath, Annegret ^a   Jungermann, Kurt ^a   Schieferdecker, Henrike L ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Glucose metabolism; Kupffer cells; Liver perfusion; Prostaglandin transporter; Prostanoid uptake; Thromboxane synthase

Indexed keywords

DALTROBAN; FUREGRELATE; GLUCOSE; GLYCOGEN PHOSPHORYLASE; IFETROBAN; PROSTAGLANDIN D2; THROMBOXANE RECEPTOR BLOCKING AGENT; THROMBOXANE SYNTHASE INHIBITOR; U 63557; BENZOFURAN DERIVATIVE; COMPLEMENT COMPONENT C5A; ENZYME INHIBITOR; FUSED HETEROCYCLIC RINGS; OXAZOLE DERIVATIVE; PHENYLACETIC ACID DERIVATIVE; SULFONAMIDE; THROMBOXANE B2; THROMBOXANE RECEPTOR; THROMBOXANE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG INFUSION; GLUCOSE METABOLISM; HORMONE RELEASE; HORMONE TRANSPORT; KUPFFER CELL; LIVER CELL; LIVER PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CELL CULTURE; DRUG ANTAGONISM; LIVER; METABOLIC CLEARANCE RATE; METABOLISM; PERFUSION; WISTAR RAT;

ANIMALS; BENZOFURANS; BICYCLO COMPOUNDS, HETEROCYCLIC; CELLS, CULTURED; COMPLEMENT C5A; ENZYME INHIBITORS; HEPATOCYTES; LIVER; MALE; METABOLIC CLEARANCE RATE; OXAZOLES; PERFUSION; PHENYLACETATES; PROSTAGLANDIN D2; RATS; RATS, WISTAR; RECEPTORS, THROMBOXANE; SULFONAMIDES; THROMBOXANE B2; THROMBOXANE-A SYNTHASE;

EID: 0142102637     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00398-8     Document Type: Article

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