Inhibition of anaphylatoxin C3a- and C5a- but not nerve stimulation- or noradrenaline-dependent increase in glucose output and reduction of flow in Kupffer cell-depleted perfused rat livers

Hepatology

Volumn 24, Issue 3, 1996, Pages 685-690

  Püschel, Gerhard P ^a   Nolte, Andreas ^a   Schieferdecker, Henrike L ^a   Rothermel, Ellen ^b   Götze, Otto ^b   Jungermann, Kurt ^a  

^a Inst F Biochem Molec Z   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHYLATOXIN; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C5A; GADOLINIUM CHLORIDE; GLUCOSE; LACTIC ACID; NORADRENALIN; PROSTANOID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; DEPLETION; GLUCONEOGENESIS; ITO CELL; KUPFFER CELL; LIVER PERFUSION; MALE; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SYMPATHETIC NERVE;

EID: 0029795655     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.1996.v24.pm0008781343     Document Type: Article

References (35)

1. Püschel GP, Oppermann M, Muschol W, Götze O, Jungermann K. Increase of glucose and lactate output and decrease of flow by human anaphylatoxin C3a but not C5a in perfused rat liver. FEBS Lett 1989;243:83-87.
2. Muschol W, Püschel GP, Hülsmann M, Jungermann K. Eicosanoid-mediated increase in glucose and lactate output as well as decrease and redistribution of flow by complement activated rat serum in perfused rat liver. Eur J Biochem 1991;196:525-530.
3. Ulken V, Püschel GP, Jungermann K. Increase in glucose and lactate output and perfusion resistance by stimulation of hepatic nerves in isolated perfused rat liver: role of α1-, α2-, β1- and β2-receptors. Biol Chem Hoppe Seyler 1991;372:401-409.
4. Gardemann A, Strulik H, Jungermann K. Different accessibility from the artery and the portal vein of alpha- and beta-receptors involved in the sympathetic nerve action on glycogenolysis and hemodynamics in perfused rat liver. Biol Chem Hoppe Seyler 1989;370:47-54.
5. Iwai M, Jungermann K. Possible involvement of eicosanoids in the actions of sympathetic hepatic nerves on carbohydrate metabolism and hemodynamics in perfused rat liver. FEBS Lett 1987;221:155-160.
6. Decker K. Biologically active products of stimulated liver macrophages (Kupffer cells). Eur J Biochem 1990;192:245-261.
7. Huber M, Keppler D. Eicosanoids and the liver. Prog Liver Dis 1990;9: 117-141.
8. 2 of glycogenolysis via an increase in inositol 1,4,5-trisphosphate in rat hepatocytes. Biochem Biophys Res Commun 1989;163:1235-1242.
9. 2-induced glucose production in rat hepatocytes. Endocrinology 1990;126:2831-2836.
10. 2 on parenchymal liver cells. Biochem J 1989;262:195-201.
11. Kawada N, Klein H, Decker K. Eicosanoid-mediated contractility of hepatic stellate cells. Biochem J 1992;285:367-371.
12. Wisse E, Geerts A, Bowens L, van Boosuyt H, Vanderkerken K, van Goethem F. Cells of the hepatic sinusoid anno 1988: an attempt to review the IVth international Kupffer cell symposium. In: Wisse E, Knook DL, Decker K. eds. Cells of the hepatic sinusoid. Rijswijk, the Netherlands: Kupffer Cell Foundation, 1989;2:1-9.
13. Püschel GP, Hespeling U, Oppermann M, Dieter P. Increase in prostanoid formation in rat liver macrophages (Kupffer cells) by human anaphylatoxin C3a. HEPATOLOGY 1993;18:1516-1521.
14. Hespeling U, Püschel GP, Jungermann K, Götze O, Zwirner J. Stimulation of glycogen phosphorylase in rat hepatocytes via prostanoid release from Kupffer cells by recombinant rat anaphylatoxin C5a but not native human C5a in hepatocyte/Kupffer cell co-cultures. FEBS Lett 1995;372:108-112.
15. 2 release from primary Ito cell cultures after noradrenaline and ATP but not adenosine. HEPATOLOGY 1994;20:142-148.
16. Bouma JMW, Smit MJ. Gadolinium chloride selectively blocks endocytosis by Kupffer cells. In: Wisse E, Knook DL, Decker K, eds. Cells of the hepatic sinusoid. Rijkswijk, the Netherlands: Kupffer Cell Foundation 1989;2:132-133.
17. Husztik E, Lazar G, Parducz A. Electron microscopic study of Kupffer-cell phagocytosis blockade induced by gadolinium chloride. Br J Exp Pathol 1980;61:624-630.
18. Hardonk MJ, Dijkhuis FW, Hulstaert CE, Koudstaal J. Heterogeneity of rat liver and spleen macrophages in gadolinium chloride-induced elimination and repopulation. J Leukoc Biol 1992;52:296-302.
19. Elsner J, Oppermann M, Czech W, Kapp A. C3a activates the respiratory burst in human polymorphonuclear neutrophilic leukocytes via pertussis toxin-sensitive G-proteins. Blood 1994;83:3324-3331.
20. Cui LX, Ferreri K, Hugli TE. Characterization of rat C5a, a uniquely active spasmogen. Complement 1985;2:18-19.
21. Nukina S, Fusaoka T, Thurman RG. Glycogenolytic effect of adenosine involves ATP from hepatocytes and eicosanoids from Kupffer cells. Am J Physiol 1994;266:G99-G102.
22. Püschel GP, Oppermann M, Neuschäfer-Rube F, Götze O, Jungermann K. Differential effects of human anaphylatoxin-C3a on glucose output and flow in rat liver during orthograde and retrograde perfusion - the periportal scavenger cell hypothesis. Biochem Biophys Res Commun 1991;176: 1218-1226.
23. Banauch D, Brümmer W, Ebeling W, Rendrey H, Seybold K, Rick R. Eine Glucose-dehydrogenase für die Glucosebestimmung in Körperflüssigkeiten. Z Klin Chem Klin Biochem 1975;13:101-107.
24. Noll F. Lactatbestimmung mit LDH, GPT und NAD. In: Bergmeyer HU, ed. Methoden der enzymatischen Analyse. Weinheim: Verlag Chemie, 1974:1521-1525.
25. Gardemann A, Jahns U, Jungermann K. Control of glycogenolysis and blood flow by arterial and portal norepinephrine in perfused liver. Am J Physiol 1991;260:E762-E771.
26. Gardemann A, Püschel GP, Jungermann K. Nervous control of liver metabolism and hemodynamics. Eur J Biochem 1992;207:399-411.
27. Häussinger D, Stehle T. Hepatocyte heterogeneity in response to icosanoids. The perivenous scavenger cell hypothesis. Eur J Biochem 1988;175: 395-403.
28. 2, phospholipase C and NADPH oxidase in cultured rat Kupffer cells. In: Wisse E, Knook DL, McCuskey RS, eds. Cells of the hepatic sinusoid. Leiden: The Kupffer Cell Foundation, the Netherlands, 1991;3: 34-36.
29. Hoedemakers RMJ, Morselt HWM, Scherphof GM, Daemen T. Heterogeneity in secretory responses of rat liver macrophages of different size. Liver 1995;15:313-319.
30. Jungermann K, Kietzmann T. Zonation of parenchymal and non-parenchymal metabolism in liver. Annu Rev Nutr 1996;16:179-203.
31. Haviland DL, McCoi RL, Whitehead WT, Akama H, Molmenti EP, Brown A, Haviland JC, et al. Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung. J Immunol 1995;154:1861-1869.
32. Buchner RR, Hugli TE, Ember JA, Morgan EL. Expression of functional receptors for human C5a anaphylatoxin (CD88) on the human hepatocellular carcinoma cell line HepG2. J Immunol 1995;155:308-315.
33. Christ B, Nath A, Bastian H, Jungermann K. Regulation of the expression of the phosphoenolpyruvate carboxykinase gene in cultured rat hepatocytes by glucagon and insulin. Eur J Biochem 1989;178:373-379.
34. Christ B, Nath A, Jungermann K. Mechanism of the inhibition by insulin of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures. Biol Chem Hoppe-Seyler 1990;371:395-402.
35. Metz W, Forsmann WG. Innervation of the liver in guinea pig and rat. Anat Embryol 1980;160:239-252.