Kupffer cell inactivation prevents lipopolysaccharide-induced structural changes in the rat liver sinusoid: An electron-microscopic study

Hepatology

Volumn 23, Issue 4, 1996, Pages 788-796

  Sarphie, Theodore G ^a   D'Souza, Nympha B ^a   Deaciuc, Ion V ^a,b  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; GADOLINIUM CHLORIDE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; GRAM NEGATIVE INFECTION; HEPATITIS; KUPFFER CELL; LIVER CELL; LIVER SINUSOID; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

EID: 0029881767     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.1996.v23.pm0008666333     Document Type: Article

References (9)

1. Bautista AP, Deaciuc IV, Jaeschke H, Spolarics Z, Spitzer JJ. Hepatic responses to bacterial endotoxin (LPS). In: Schlag G, Redl H, eds. Pathophysiology of shock, sepsis and organ failure. Berlin, Heidelberg: Springer Verlag, 1993:915-934.
2. Deaciuc IV, Bagby GJ, Niesman MR, Skrepnik N, Spitzer JJ. Modulation of hepatic sinusoidal endothelial cell function by Kupffer cells: an example of intercellular communication in the liver. HEPATOLOGY 1994;19:464-470.
3. Iimuro Y, Yamamoyo M, Kohno H, Itakura J, Fuji H, Matsumoto Y. Blockade of liver macrophages by gadolinium chloride reduces lethality in endotoxemic rats - analysis of mechanisms of lethality in endotoxemia. J Leukoc Biol 1994;55:723-728.
4. Bautista AP, Skrepnik N, Niesman MR, Bagby GJ. Elimination of macrophages by liposome-encapsulated dichloromethylene diphosphonate suppresses the endotoxin-induced priming of Kupffer cells. J Leukoc Biol 1994;55:321-327.
5. Arai M, Mochida S, Ohno A, Ogata I, Fujiwara K. Sinusoidal endothelial cell damage by activated macrophages in rat liver necrosis. Gastroenterology 1993;104:1466-1471.
6. Kuiper J, Casteleyn E, Van Berkel TJC. Regulation of liver metabolism by intercellular communication. Adv Enzyme Regul 1988;27:193-208.
7. Altin JG, Bygrave FL. Non-parenchymal cells as mediators of physiological responses in liver. Mol Cell Biochem 1988;83:3-14.
8. Eriksson S, Fraser JRE, Laurent TC, Pertoft H, Smedsrod B. Endothelial cells are a site of uptake and degradation of hyaluronic acid in the liver. Exp Cell Res 1983;144:223-228.
9. Deaciuc IV, Bagby GJ, Lang CH, Spitzer JJ. Hyaluronic acid uptake by the isolated, perfused rat liver: an index of hepatic sinusoidal endothelial cell function. HEPATOLOGY 1993;17:266-272.