Increased c-Fos expression in the centromedial nucleus of the thalamus in metabotropic glutamate 8 receptor knockout mice following the elevated plus maze test

Neuroscience

Volumn 121, Issue 1, 2003, Pages 167-178

  Linden, A M ^a   Baez, M ^a   Bergeron, M ^a   Schoepp, D D ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Central medial thalamic nucleus; Immediate early gene; Intralaminar thalamic nuclei; Metabotropic glutamate receptors

Indexed keywords

METABOTROPIC RECEPTOR; PROTEIN C FOS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ANXIETY DISORDER; ARTICLE; BRAIN REGION; CELL ACTIVATION; CONTROLLED STUDY; DENTATE GYRUS; DISEASE ASSOCIATION; EMBRYO; FEMALE; GRANULAR CELL; IN VIVO STUDY; KNOCKOUT MOUSE; MALE; MAZE TEST; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PYRIFORM CORTEX; REGULATORY MECHANISM; SENSORY SYSTEM; SIGNAL TRANSDUCTION; STRESS; THALAMUS NUCLEUS; WILD TYPE;

EID: 0142028236     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(03)00393-2     Document Type: Article

References (50)

1. Belzung C., Griebel G. Measuring normal and pathological anxiety-like behaviour in mice a review . Behav Brain Res. 125:2001;141-149.
2. Beracochea D.J., Krazem A. Effects of mamillary body and mediodorsal thalamic lesions on elevated plus maze exploration. Neuroreport. 2:1991;793-796.
3. Bushell T.J., Jane D.E., Tse H.W., Watkins J.C., Garthwaite J., Collingridge G.L. Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices. Br J Pharmacol. 117:1996;1457-1462.
4. Cartmell J., Schoepp D.D. Regulation of neurotransmitter release by metabotropic glutamate receptors. J Neurochem. 75:2000;889-907.
5. Chowdhury G.M.I., Fujioka T., Nakamura S. Induction and adaptation of Fos expression in the rat brain by two types of acute restraint stress. Brain Res Bull. 52:2000;171-182.
6. Conn P.J., Pin J.-P. Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharmacol Toxicol. 37:1997;205-237.
7. Duncan G., Knapp D., Breese G. Neuroanatomical characterization of Fos induction in rat behavioural models of anxiety. Brain Res. 713:1996;79-91.
8. Duvoisin R.M., Zhang C., Ramonell K. A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb. J Neurosci. 15:1995;3075-3083.
9. Franklin K.B.J., Paxinos G. The mouse brain in stereotaxic coordinates. 1997;Academic Press Inc, San Diego.
10. Gerlai R., Adams B., Fitch T., Chaney S., Baez M. Performance deficits of mGluR8 knockout mice in learning tasks the effects of null mutation and the background genotype . Neuropharmacology. 43:2002;235-249.
11. Glenn L.L., Steriade M. Discharge rate and excitability of cortically projecting intralaminar thalamic neurons during waking and sleep states. J Neurosci. 2:1982;1387-1404.
12. Graeff F.G., Silveira M.C.L., Nogueira R.L., Audi E.A., Oliveira R.M.W. Role of the amygdala and periaqueductal gray in anxiety and panic. Behav Brain Res. 58:1993;123-131.
13. Griebel G., Belzung C., Perrault G., Sanger D.J. Differences in anxiety-related behaviours and in sensitivity to diazepam in inbred and outbred strains of mice. Psychopharmacology. 148:2000;164-170.
14. Groenewegen H.J., Berendse H.W. The specificity of the 'nonspecific' midline and intralaminar thalamic nuclei. Trends Neurosci. 17:1994;52-57.
15. Hinks G.L., Brown P., Field M., Poat J.A., Hughes J. The anxiolytics CI-988 and chlordiazepoxide fail to reduce immediate early gene mRNA stimulation following exposure to the rat elevated X-maze. Eur J Pharmacol. 312:1996;153-161.
16. Hogg S. A review of the validity and variability of the elevated plus-maze as an animal model of anxiety. Pharmacol Biochem Behav. 54:1996;21-30.
17. Hughes P., Dragunow M. Induction of immediate early genes and the control of neurotransmitter-regulated gene-expression within the nervous system. Pharmacol Rev. 47:1995;133-178.
18. Kinomura S., Larsson J., Gulyas B., Roland P.F. Activation by attention of the human reticular formation and thalamic intralaminar nuclei. Science. 271:1996;512-515.
19. Kinoshita A., Ohishi H., Neki A., Nomura S., Shigemoto R., Takada M., Nakanishi S., Mizuno N. Presynaptic localization of a metabotropic glutamate receptor, mGluR8, in the rhinencephalic areas a light and electron microscopy study in the rat . Neurosci Lett. 207:1996;61-64.
20. Kishimoto T., Radulovic J., Radulovic M., Lin C.R., Schrick C., Hooshmand F., Hermanson O., Rosenfeld M.G., Spiess J. Deletion of Crhr2 reveals an anxiolytic role for corticostropin-releasing hormone receptor-2. Nat Gen. 24:2000;415-419.
21. Koulen P., Brandstatter J.H. Pre- and postsynaptic sites of action of mGlu8a in the mammalian retina. Inv Opht Vis Sci. 43:2002;1933-1940.
22. Koulen P., Kuhn R., Wassle H., Brandstatter J.H. Modulation of the intracellular calcium concentration in photoreceptor terminals by a presynaptic metabotropic glutamate receptor. Proc Natl Acad Sci USA. 96:1999;9909-9914.
23. Krout K.E., Belzer R.E., Loewy A.D. Brainstem projections to midline and intralaminar thalamic nuclei of the rat. J Comp Neurol. 448:2002;53-101.
24. Krout K.E., Loewy A.D. Periaqueductal gray matter projection to midline and intralaminar thalamic nuclei of the rat. J Comp Neurol. 424:2000;111-141.
25. Krout K.E., Loewy A.D. Parabrachial nucleus projections to midline and intralaminar thalamic nuclei of the rat. J Comp Neurol. 428:2000;475-494.
26. Krout K.E., Loewy A.D., Westby G.W., Redgrave P. Superior colliculus projections to midline and intralaminar thalamic nuclei of the rat. J Comp Neurol. 431:2001;198-216.
27. Linden A.-M., Johnson B.G., Peters S.C., Shannon H.E., Tian M., Wang Y., Yu J.L., Koster A., Baez M., Schoepp D.D. Increased anxiety-related behavior in mice deficient for metabotropic glutamate 8 (mGlu8) receptor. Neuropharmacology. 43:2002;251-259.
28. Lister R.G. The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology. 92:1987;180-185.
29. Messenger M.J., Dawson L.G., Duty S. Changes in metabotropic glutamate receptor 1-8 gene expression in the rodent basal ganglia motor loop following lesion of the nigrostriatal tract. Neuropharmacology. 43:2002;261-271.
30. Mitchell S.J., Silver R.A. Glutamate spillover suppresses inhibition by acting presynaptic mGluRs. Nature. 404:2000;498-502.
31. Moldrich R.X., Beart P.M., Jane D.E., Chapman A.G., Meldrum B.S. Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice. Neuropharmacology. 40:2001;732-735.
32. Price J.L. Thalamus. Paxinos G. The rat nervous system. 2nd edn :1995;629-648 Academic Press Inc, New York.
33. Rusakov D.A., Kullmann D.M. Extrasynaptic glutamate diffusion in the hippocampus ultrastructural constraints, uptake, and receptor activation . J Neurosci. 18:1998;3158-3170.
34. Ryabinin A.E., Wang Y.-M., Finn D.A. Different levels of fos immunoreactivity after repeated handling and injection stress in two inbred strains of mice. Pharmacol Biochem Behav. 63:1999;143-151.
35. Salt T.E., Eaton S.A. Distinct presynaptic metabotropic receptors for L-AP4 and CCGl on GABAergic terminals pharmacological evidence using novel alpha-methyl derivative mGluR agonists, MAP4 and MCCG, in the rat thalamus in vivo . Neuroscience. 65:1995;5-13.
36. Saugstad J.A., Kinzie J.M., Shinohara M.M., Segerson T.P., Westbrook G.L. Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile. Mol Pharmacol. 51:1997;119-125.
37. Scanziani M., Salin P.A., Vogt K.E., Malenka R.C., Nicoll R.A. Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors. Nature. 385:1997;630-634.
38. Schoepp D.D. Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system. J Pharmacol Exp Ther. 299:2001;12-20.
39. Schoepp D.D., Jane D.E., Monn J.A. Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology. 38:1999;1431-1476.
40. Senba E., Matsunaga K., Tohyama M., Noguchi K. Stress-induced c-fos expression in the rat brain activation mechanism of sympathetic pathway . Brain Res Bull. 31:1993;329-344.
41. Shigemoto R., Kinoshita A., Wada E., Nomura S., Ohishi H., Takada M., Flor P.J., Neki A., Abe T., Nakanishi S., Mizuno N. Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus. J Neurosci. 17:1997;7503-7522.
42. Silveira M.C.L., Zangrossi H.J., Viana MdB, Silveira R., Graeff F.G. Differential expression of Fos protein in the rat brain induced by performance of avoidance or escape in the elevated T-maze. Behav Brain Res. 126:2001;13-21.
43. Steriade M. Arousal revisiting the reticular activating system . Science. 272:1996;225-226.
44. Steriade M. Brainstem activation of thalamocortical systems. Brain Res Bull. 50:1999;391-392.
45. Stone E.A., Zhang Y. Adrenoceptor antagonists block c-fos response to stress in the mouse brain. Brain Res. 694:1995;279-286.
46. Thomas N.K., Wright R.A., Howson P.A., Kingston A.E., Schoepp D.D., Jane D.E. (S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord. Neuropharmacology. 40:2001;311-318.
47. 3H]amino-4-phosphonobutyrate binding in mouse brain. J Neurochem. 72:1999;835-840.
48. Trullas R., Skolnick P. Differences in fear motivated behaviors among inbred mouse strains. Psychopharmacology. 111:1993;323-331.
49. Wada E., Shigemoto R., Kinoshita A., Ohishi H., Mizuno N. Metabotropic glutamate receptor subtypes in axon terminals of projection fibers from the main and accessory olfactory bulbs a light and electron microscopic immunohistochemical study in the rat . J Comp Neurol. 393:1998;493-504.
50. Zhai J., Tian M.T., Wang Y., Yu J.L., Koster A., Baez M., Nisenbaum E.S. Modulation of lateral perforant path excitatory responses by metabotropic glutamate 8 (mGlu8) receptors. Neuropharmacology. 43:2002;223-230.