Modulation of lateral perforant path excitatory responses by metabotropic glutamate 8 (mGlu8) receptors

Neuropharmacology

Volumn 43, Issue 2, 2002, Pages 223-230

  Zhai, Jin ^a   Tian, Ming Ting ^a   Wang, Yi ^a   Yu, Jian Liang ^a   Köster, Anja ^a   Baez, Melvyn ^a   Nisenbaum, Eric S ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Autoreceptor; Dentate gyrus; Entorhinal cortex; Metabotropic; mGluR; Perforant path

Indexed keywords

2 AMINO 4 PHOSPHONOBUTYRIC ACID; 3,4 DICARBOXYPHENYLGLYCINE; 4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; ALPHA METHYLSERINE O PHOSPHATE; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR ANTAGONIST; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; KNOCKOUT GENE; NEUROMODULATION; NONHUMAN; PERFORANT NERVE TRACT; PRIORITY JOURNAL;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PERFORANT PATHWAY; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 0036669426     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00087-4     Document Type: Article

References (25)

1. Bradley S.R., Levey A.I., Hersch S.M., Conn P.J. Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies. Journal of Neuroscience. 16:1996;2044-2056.
2. Chapman A.G., Nanan K., Yip P., Meldrum B.S. Anticonvulsant activity of a metabotropic glutamate receptor 8 preferential agonist, (R,S) -4-phosphonophenylglycine. European Journal of Pharmacology. 383:1999;23-27.
3. Conn P.J., Pin J.P. Pharmacology and functions of metabotropic glutamate receptors. Annual Review of Pharmacology and Toxicology. 37:1997;205-237.
4. Dietrich D., Beck H., Kral T., Clusmann H., Elger C.E., Schramm J. Metabotropic glutamate receptors modulate synaptic transmission in the perforant path: pharmacology and localization of two distinct receptors. Brain Research. 767:1997;220-227.
5. Dietrich D., Kral T., Clusmann H., Friedl M., Schramm J. Reduced function of L-AP4-sensitive metabotropic glutamate receptors in human epileptic sclerotic hippocampus. European Journal of Neuroscience. 11:1999;1109-1113.
6. Duvoisi R.M., Zhang C., Ramonell K. A novel metabotropic glutamate receptor expressed in the retina and olfractory bulb. J. Neurosci. 15:1995;3075-3083.
7. Ferbinteanu J., Holsinger R.M., McDonald R.J. Lesions of the medial or lateral perforant path have different effects on hippocampal contributions to place learning and on fear conditioning to context. Behavioral Brain Research. 101:1999;65-84.
8. Irwin S. Comprehensive observational assessment: IA. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse. Psychopharmacologia. 13:1968;222-257.
9. Ito I., Kohda A., Tanabe S., Hirose E., Hayashi E., Mitsunaga S., Sugiyama H. 3,5-dihydroxyphenylglycine: a potent agonist of metabotropic glutamate receptors. Neuroreport. 3:1992;1013-1016.
10. Johansen P.A., Chase L.A., Sinor A.D., Koerner J.F., Johnson R.L., Robinson M.B. Type 4a metabotropic glutamate receptor: identification of new potent agonists and differentiation from the L-(+)-2-amino-4-phosphonobutanoic acid-sensitive receptor in the lateral perforant pathway in rats. Molecular Pharmacology. 48:1995;140-149.
11. Kinoshita A., Shigemoto R., Ohishi H., van der Putten H., Mizuno N. Immunohistochemical localization of metabotropic glutamate receptors, mGluR7a and mGluR7b, in the central nervous system of the adult rat and mouse: a light and electron microscopic study. Journal of Comparative Neurology. 393:1998;332-352.
12. Klapstein G.J., Meldrum B.S., Mody I. Decreased sensitivity to Group III mGluR agonists in the lateral perforant path following kindling. Neuropharmacology. 38:1999;927-933.
13. Koerner J.F., Cotman C.W. Micromolar L-2-amino-4-phosphonobutyric acid selectively inhibits perforant path synapses from lateral entorhinal cortex. Brain Research. 216:1981;192-198.
14. Köster A., Montkowski A., Schulz S., Stube E.M., Knaudt K., Jenck F., Moreau J.L., Nothacker H.P., Civelli O., Reinscheid R.K. Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice. Proceedings of the National Academy of Sciences USA. 96:1999;10444-10449.
15. Linden A.-M., Johnson B.G., Peters S.C., Shannon H.E., Tian M., Wang Y., Yu J.L., Köster A., Baez M., Schoepp D.D. Increased anxiety-related behavior in mice deficient for metabotropic glutamate 8 (mGlu8) receptor. Neuropharmacology. 43:(2):2002;251-259.
16. Macek T.A., Winder D.G., Gereau IV R.W., Ladd C.O., Conn P.J. Differential involvement of group II and group III mGluRs as autoreceptors at lateral and medial perforant path synapses. Journal of Neurophysiology. 76:1996;3798-3806.
17. McNaughton B.L. Evidence for two physiologically distinct perforant pathways to the fascia dentata. Brain Research. 199:1980;1-19.
18. Moldrich R.X., Beart P.M., Jane D.E., Chapman A.G., Meldrum B.S. Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice. Neuropharmacology. 40:2001;732-735.
19. O'Leary D.M., Cassidy E.M., O'Connor J.J. Group II and III metabotropic glutamate receptors modulate paired pulse depression in the rat dentate gyrus in vitro. European Journal of Pharmacology. 340:1997;35-44.
20. Pin J.-P., Duvoisin R. The metabotropic glutamate receptors: structure and functions. Neuropharmacology. 34:1995;1-26.
21. Saugstad J.A., Kinzie J.M., Mulvihill E.R., Segerson T.P., Westbrook G.L. Cloning and expression of a new member of the L-2-amino-4- phosphonobutyric acid-sensitive class of metabotropic glutamate receptors. Molecular Pharmacology. 45:1994;367-372.
22. Schoepp D.D., Jane D.E., Monn J.A. Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology. 38:1999;1431-1476.
23. Shigemoto R., Kinoshita A., Wada E., Nomura S., Ohishi H., Takada M., Flor P.J., Neki A., Abe T., Nakanishi S., Mizuno N. Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus. Journal of Neuroscience. 17:1997;7503-7522.
24. Tatarczynska E., Klodzinska A., Kroczka B., Chojnacka-Wojcik E., Pilc A. The antianxiety-like effects of antagonists of group I and agonists of group II and III metabotropic glutamate receptors after intrahippocampal administration. Psychopharmacology (Berlin). 158:2001;94-99.
25. Thomas N.K., Wright R.A., Howson P.A., Kingston A.E., Schoepp D.D., Jane D.E. (S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal spinal cord. Neuropharmacology. 40:2001;311-318.