Local and peripheral cytokine response and CagA status of Helicobacter pylori-positive patients with duodenal ulcer

European Cytokine Network

Volumn 14, Issue 3, 2003, Pages 143-148

  Klausz, Gergely ^a   Tiszai, Andrea ^a   Tiszlavicz, László ^a   Gyulai, Zsófia ^a   Lénárt, Zsuzsa ^a   Lonovics, János ^a   Mándi, Yvette ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

CagA; Cytokine; ELISA; H. pylori; Nitrotyrosine; Western blot

Indexed keywords

3 NITROTYROSINE; CAGA PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BIOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE RELEASE; DUODENUM ULCER; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HELICOBACTER INFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; INTESTINE MUCOSA; MALE; STATISTICAL SIGNIFICANCE; STOMACH ANTRUM; WESTERN BLOTTING;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BIOPSY; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; GASTRIC MUCOSA; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INTERLEUKINS; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS); HELICOBACTER; HELICOBACTER PYLORI;

EID: 0141992111     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Meryn S. 1994. Helicobacter pylori: quo vadis? Wien. Clin. Wochenschr. 106: 535.
2. Rudnicka W, Andersen P A. 1999. Inflammation and host response. Curr. Opin. Gastroenterol. 15: S17.
3. Crabtree JE. 1998. Role of cytokines in pathogenesis of Helicobacter pylori-induced mucosal damage. (Review) Dig. Dis. Sci. 43: 46S.
4. van Doorn LJ, Figueiro do C, Sanna R, Plaisier A, Schneeberger P. de Boer W, Quint W. 1998. Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori. Gastroenterology 115: 58.
5. Crabtree JE, Farmery SM, Lindley IJ, Figura N, Peichl P, Tomkins DS. 1994. Cag A/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell. J. Clin. Pathol. 47: 945.
6. de Waal Malefyt R, Abrams J, Bennett B, Figdor GG, de Vries JB. 1991. Interleukin-10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174: 1209.
7. Wang P, Wu P, Siegel MI, Egan RW, Billah MM. 1995. Interleukin-10 inhibits NFkB activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms. J. Biol. Chem. 270: 9558.
8. Felley CP, Pignatelli B, Van Melle GD, Crabtree JE, Stolte M, Diezi J, Corthesy-Theulaz I, Michetti P, Bancel MB, Patricot LM, Ohshima H, Felley-Bosco E. 2002. Oxidative stress in gastric mucosa of asymptomatic humans infected with Helicobacter pylori: effect of bacterial eradication. Helicobacter 7: 342.
9. Beckmann JS, Ye YZ, Anderson PG, Chen J, Accavitti MA, Tarpey MM, White CR. 1994. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunochemistry. Biol. Chem. Hoppe Seyler 315: 81.
10. Girault I, Karu AE, Schaper M, Barcellos-Hoff MH, Hagen T, Vogel DS, Ames BN, Christen S, Shigenaga MK. 2001. Immuno-detection of 3-nitrotyrosine in the liver of zymosan-treated rats with a new monoclonal antibody: comparison to analysis by HPLC. Free Rad. Biol. Med. 31: 1375.
11. Sipponen P, Kekki M, Siurala M. 1991. The Sydney System: epidemiology and natural history of chronic gastritis. (Review) J. Gastroenterol. Hepatol. 6: 244.
12. Bickley J, Owen RJ, Fraser AG, Pounder RE. 1993. Evaluation of the polymerase chain reaction for detecting the urease C gene of Helicobacter pylori in gastric biopsy samples and dental plaque. J. Med. Microbiol. 39: 338.
13. van Zwet AA, Thijs JC, Kooistra-Smid AM, Schrim J, Snijder JA. 1993. Sensitivity of culture compared with that of polymerase chain reaction for detection of Helicobacter pylori from antral biopsy samples. J. Clin. Microbiol. 31: 1918.
14. Peterson GL. 1977. A simplification of the protein assay method of Lowry et al which is more generally applicable. Anal. Biochem. 83: 346.
15. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680.
16. Berg DE, Gilman RH, Lelwala-Guruge J, Srivastava K, Valdez Y, Watanabe J, Miyagi J, Akopyants NS, Ramirez-Ramos A, Yoshiwara TH, Recavarren S, Leon-Barua R. 1997. Helicobacter pylori populations in Peruvian patients. Clin. Inf. Dis. 25: 996.
17. D'Elios MM, Amedei A, Del Prete G. 1999. Host response to Helicobacter pylori infection: the Th1 2 balance. Clin. Microbiol. Infect. 5 Suppl 3: 42.
18. Glocker E, Lange C, Covacci A, Bereswill S, Kist M, Pahl HL. 1998. Proteins encoded by the cag pathogenicity island of Helicobacter pylori are required for NF-êB activation. Infect. Immun. 66: 2346.
19. Labigne A, de Reuse H. 1996. Determinants of Helicobacter pylori pathogenicity. (Review) Infect. Agents Dis. 5: 191.
20. Kooy NW, Royall JA, Ye YZ, Kelly DR, Beckman JS. 1995. Evidence for in vivo peroxynitrite production in human acute lung injury. Am. J. Respir. Crit. Care Med. 151: 1250.
21. Zingarelli B, O'Connor M, Wong H, Salzman AL, Szabó C. 1996. Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide. J. Immunol. 156: 350.
22. Sharma SA, Tummuru MK, Blaser MJ, Kerr LD. 1998. Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor Kappa B in gastric epithelial cells. J. Immunol. 160: 2401.
23. Gerard M, Rad R, Prinz C, Naumann M. 2002. Pathogenesis of Helicobacter pylori infection. (Review) Helicobacter 7: 17.