Changes in dopaminergic neurotransmission do not alter somatic or motivational opiate withdrawal-induced symptoms in rats

Behavioral Neuroscience

Volumn 117, Issue 5, 2003, Pages 995-1005

  Caillé, Stéphanie ^a,d   Espejo, Emilio F ^c   Rodriguez Arias, Marta ^b   Minarro, Jose ^b   Cador, Martine ^a   Stinus, Luis ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b UNIVERSITY OF VALENCIA   (Spain)

^c UNIVERSITY OF SEVILLE   (Spain)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOMORPHINE; DOPAMINE; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; DROPERIDOL; FLUPENTIXOL; MORPHINE; NALOXONE; OPIATE; OXIDOPAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVERSION; CONTROLLED STUDY; DOPAMINE BRAIN LEVEL; DOPAMINERGIC TRANSMISSION; LONG TERM EXPOSURE; MALE; MOTIVATION; NONHUMAN; NUCLEUS ACCUMBENS; RAT; SOMATIZATION; SYMPTOMATOLOGY; WITHDRAWAL SYNDROME;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MOTIVATION; NALOXONE; NARCOTICS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE; SUBSTANCE WITHDRAWAL SYNDROME; SYNAPTIC TRANSMISSION;

EID: 0141988769     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.117.5.995     Document Type: Article

References (50)

1. Acquas, E., Carboni, E., & Di Chiara, G. (1991). Profound depression of mesolimbic dopamine release after morphine withdrawal in dependent rats. European Journal of Pharmacology, 193, 133-134.
2. Bassareo, V., Tanda, G., & Di Chiara, G. (1995). Increase of extracellular dopamine in the medial prefrontal cortex during spontaneous and naloxone-precipitated opiate abstinence. Psychopharmacology, 122, 202-205.
3. Caillé, S., Georges, F., Le Moine, C., Cador, M., & Stinus, L. (2000, June). Involvement of dopamine neurotransmission in opiate dependence. Paper presented at the Federation of European Neuroscience Societies meeting, Brighton, England.
4. Cliffer, K. D., Burstein, R., & Giesler, G. J., Jr. (1991). Distributions of spinothalamic, spinohypothalamic, and spinotelencephalic fibers revealed by anterograde transport of PHA-L in rats. Journal of Neuroscience, 11, 852-868.
5. Delfs, J. M., Zhu, Y., Druhan, J. P., & Aston-Jones, G. (2000, January 27). Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion. Nature, 403, 430-434.
6. Diana, M., Muntoni, A., Pistis, M., Melis, M., & Gessa, G. (1999). Lasting reduction in mesolimbic dopamine neuronal activity after morphine withdrawal. European Journal of Neuroscience, 11, 1037-1041.
7. Diana, M., Pistis, M., Muntoni, A., & Gessa, G. (1995). Profound decrease of mesolimbic dopaminergic neuronal activity in morphine withdrawn rats. Journal of Pharmacology and Experimental Therapeutics, 272, 781-785.
8. Di Chiara, G. (1995). The role of dopamine in drug abuse viewed from the perspective of its role in motivation. Drug and Alcohol Dependence, 38, 95-137.
9. Dugast, C., Suaud-Chagny, M. F., & Gonon, F. (1994). Continuous in vivo monitoring of evoked dopamine release in the rat nucleus accumbens by amperometry. Neuroscience, 62, 647-654.
10. Espejo, E. F., Serrano, M. I., Caillé, S., & Stinus, L. (2001). Behavioral expression of opiate withdrawal is altered after prefrontocortical dopamine depletion in rats' monoaminergic correlates. Neuropsychopharmacology, 25, 204-212.
11. Fiserova, M., Consolo, S., & Krsiak, M. (1999). Chronic morphine induces long-lasting changes in acetylcholine release in rat nucleus accumbens core and shell: An in vivo microdialysis study. Psychopharmacology, 142, 85-94.
12. Gellert, V. F., & Holtzman, S. G. (1978). Development and maintenance of morphine tolerance and dependence in the rat by scheduled access to morphine drinking solutions. Journal of Pharmacology and Experimental Therapeutics, 205, 536-546.
13. Georges, F., Stinus, L., & Le Moine, C. (2000). Mapping of c-fos gene expression in the brain during morphine dependence and precipitated withdrawal, and phenotypic identification of the striatal neurons involved. European Journal of Neuroscience, 12, 4475-4486.
14. Gold, L. H., Stinus, L., Inturrisi, C. E., & Koob, G. F. (1994). Prolonged tolerance, dependence and abstinence following subcutaneous morphine pellet implantation in the rat. European Journal of Pharmacology, 253, 45-51.
15. Harris, G. C., & Aston-Jones, G. (1994, September 8). Involvement of D2 dopamine receptors in the nucleus accumbens in the opiate withdrawal syndrome. Nature, 371, 155-157.
16. Hayward, M. D., Duman, R. S., & Nestler, E. J. (1990). Induction of the c-Fos proto-oncogene during opiate withdrawal in the locus coeruleus and other regions of rat brain. Brain Research, 525, 256-266.
17. Heyer, E. J., & Flood, P. (2000). Droperidol suppresses spontaneous electrical activity in neurons cultured from ventral midbrain. Implications for neuroleptanesthesia. Brain Research, 863, 20-24.
18. Higgins, G., Nguyen, P., Joharchi, N., & Sellers, E. M. (1991). Effects of 5HT3 receptor antagonists on behavioural measures of naloxone-precipitated opioid withdrawal. Psychopharmacology, 105, 322-328.
19. Invernizzi, R., Belli, S., & Samanin, R. (1992). Citalopram's ability to increase the extracellular concentrations of serotonin in the dorsal raphe prevents the drug's effect in the frontal cortex. Brain Research, 584, 322-324.
20. Jaffe, J. H. (1990). Drug addiction and drug abuse. In A. G. Gilman, T. W. Rall, A. S. Nies, & T. Palmer (Eds.), Goodman and Gilman's the pharmacological basis of therapeutics (pp. 522-573). New York: Pergamon Press.
21. Kelley, A. E., & Stinus, L. (1985). Disappearance of hoarding behavior after 6-hydroxydopamine lesions of the mesolimbic dopamine neurons and its reinstatement with L-dopa. Behavioral Neuroscience, 99, 531-545.
22. Kelsey, J. E., & Arnold, S. R. (1994). Lesions of the dorsomedial amygdala, but not the nucleus accumbens, reduce the aversiveness of morphine withdrawal in rats. Behavioral Neuroscience, 108, 1119-1127.
23. Koob, G. F., & Bloom, F. E. (1988, November 4). Cellular and molecular mechanisms of drug dependence. Science, 242, 715-722.
24. Koob, G. F., & Le Moal, M. (1997, October 3). Drug abuse: Hedonic homeostatic dysregulation. Science, 278, 52-58.
25. Koob, G. F., Stinus, L., & Le Moal, M. (1981). Hyperactivity and hypoactivity produced by lesions to the mesolimbic dopamine system. Behavioural Brain Research, 3, 341-359.
26. Koob, G. F., Wall, T. L., & Bloom, F. E. (1989). Nucleus accumbens as a substrate for the aversive stimulus effects of opiate withdrawal. Psychopharmacology, 98, 530-534.
27. Maldonado, R., Stinus, L., Gold, L. H., & Koob, G. F. (1992). Role of different brain structures in the expression of the physical morphine withdrawal syndrome. Journal of Pharmacology and Experimental Therapeutics, 261, 669-677.
28. Markou, A., & Koob, G. F. (1991). Postcocaine anhedonia. An animal model of cocaine withdrawal. Neuropsychopharmacology, 4, 17-26.
29. Martin, G., Nie, Z., & Siggins, G. R. (1997). mu-Opioid receptors modulate NMDA receptor-mediated responses in nucleus accumbens neurons. Journal of Neuroscience, 17, 11-22.
30. Martin, G., Przewlocki, R., & Siggins, G. R. (1999). Chronic morphine treatment selectively augments metabotropic glutamate receptor-induced inhibition of N-methyl-D-aspartate receptor-mediated neurotransmission in nucleus accumbens. Journal of Pharmacology and Experimental Therapeutics, 288, 30-35.
31. Napier, T. C., & Mitrovic, I. (1999). Opioid modulation of ventral pallidal inputs. Annals of the New York Academy of Sciences, 877, 176-201.
32. National Institutes of Health. (1986). Guide for the care and use of laboratory animals (DHEW Publication No. 86-23). Washington, DC: U.S. Government Printing Office.
33. Nestler, E. J. (2001). Molecular basis of long-term plasticity underlying addiction. Nature Reviews: Neuroscience, 2, 119-128.
34. Pellegrino, L. J., Pellegrino, A. S., & Cushman, A. J. (1979). A stereotaxic atlas of the rat brain (2nd ed.). New York: Plenum Press.
35. Pothos, E., Rada, P., Mark, G. P., & Hoebel, B. G. (1991). Dopamine microdialysis in the nucleus accumbens during acute and chronic morphine, naloxone-precipitated withdrawal and clonidine treatment. Brain Research, 566, 348-350.
36. Rada, P., Pothos, E., Mark, G. P., & Hoebel, B. G. (1991). Microdialyse evidence that acethylcholine in the nucleus accumbens is involved in morphine withdrawal and its treatment with clonidine. Brain Research, 561, 354-356.
37. Rasmussen, K. (1995). The role of the locus coeruleus and N-methyl-D-aspartic acid (NMDA) and AMPA receptors in opiate withdrawal. Neuropsychopharmacology, 13, 295-300.
38. Robert, C., Limoge, A., & Stinus, L. (1999). Transcranial electrical stimulation (Limoge's currents) potentiates the inhibition of righting reflex induced by droperidol in rats. Brain Research, 822, 132-141.
39. Rossetti, Z. L., Melis, F., Carboni, S., & Gessa, G. L. (1992). Dramatic depletion of mesolimbic extracellular dopamine after withdrawal from morphine, alcohol or cocaine: A common neurochemical substrate for drug dependence. Annals of the New York Academy of Sciences, 654, 513-516.
40. Santi, A. N., & Parker, L. A. (2001). The dopamine antagonist, alpha-flupenthixol, interferes with naloxone-induced place aversion learning, but not with acute opiate dependence in rats. Pharmacology, Biochemistry and Behavior, 70, 193-197.
41. Schulteis, G., Markou, A., Gold, L. H., Stinus, L., & Koob, G. F. (1994). Relative sensitivity to naloxone of multiple indices of opiate withdrawal: A quantitative dose-response analysis. Journal of Pharmacology and Experimental Therapeutics, 271, 1391-1398.
42. Sepulveda, M. J., Hernandez, L., Rada, P., Tucci, S., & Contreras, E. (1998). Effect of precipitated withdrawal on extracellular glutamate and aspartate in the nucleus accumbens of chronically morphine-treated rats: An in vivo microdialysis study. Pharmacology, Biochemistry, and Behavior, 60, 255-262.
43. Shippenberg, T. S., & Elmer, G. I. (1998). The neurobiology of opiate reinforcement. Critical Reviews in Neurobiology, 12, 267-303.
44. Shoji, Y., Delfs, J. M., & Williams, J. T. (1999). Presynaptic inhibition of GABA-B mediated synaptic potentials in the ventral tegmental area during morphine withdrawal. Journal of Neuroscience, 19, 2347-2355.
45. Solomon, R. L. (1980). The opponent process theory of acquired motivation: The costs of pleasure and the benefits of pain. American Psychologist, 35, 691-712.
46. Stinus, L., Caillé, S., & Koob, G. F. (2000). Opiate withdrawal induced place aversion lasts for up to 16 weeks. Psychopharmacology, 149, 115-120.
47. Stinus, L., Le Moal, M., & Koob, G. F. (1990). Nucleus accumbens and amygdala are possible substrates for the aversive stimulus effects of opiate withdrawal. Neuroscience, 37, 767-773.
48. Ungerstedt, U. (1971). Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system. Acta Physiologica Scandinavica, 367(Suppl. 367), 69-93.
49. Valverde, O., Tzavara, E., Hanoune, J., Roques, B. P., & Maldonado, R. (1996). Protein kinases in the rat nucleus accumbens are involved in the aversive component of opiate withdrawal. European Journal of Neuroscience, 8, 2671-2678.
50. Walters, C. L., Aston-Jones, G., & Druhan, J. P. (2000). Expression of fos-related antigens in the nucleus accumbens during opiate withdrawal and their attenuation by a D2 dopamine receptor agonist. Neuropsychopharmacology, 23, 307-315.