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Volumn 368, Issue 3, 2003, Pages 234-238

β-Amyloid prevents excitotoxicity via recruitment of glial glutamate transporters

Author keywords

Alzheimer's disease; Amino acid transport system; Amyloid beta protein; Astrocytes; Cell death; Glutamic acid

Indexed keywords

AMYLOID BETA PROTEIN; GLUTAMATE TRANSPORTER; GLUTAMATE TRANSPORTER INHIBITOR; GLUTAMIC ACID; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

EID: 0141958911     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-003-0792-6     Document Type: Article
Times cited : (5)

References (27)
  • 1
    • 0034062026 scopus 로고    scopus 로고
    • Evaluation of L-glutamate clearance capacity of cultured rat cortical astrocytes
    • Abe K, Abe Y, Saito H (2000) Evaluation of L-glutamate clearance capacity of cultured rat cortical astrocytes. Biol Pharmaceut Bull 23:204-207
    • (2000) Biol Pharmaceut Bull , vol.23 , pp. 204-207
    • Abe, K.1    Abe, Y.2    Saito, H.3
  • 2
    • 0023260545 scopus 로고
    • Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells
    • Brew H, Attwell D (1987) Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells. Nature 327:707-709
    • (1987) Nature , vol.327 , pp. 707-709
    • Brew, H.1    Attwell, D.2
  • 5
    • 0023106967 scopus 로고
    • A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease
    • Davies CA, Mann DM, Sumpter PQ, Yates PO (1987) A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease. J Neurol Sci 78:151-164
    • (1987) J Neurol Sci , vol.78 , pp. 151-164
    • Davies, C.A.1    Mann, D.M.2    Sumpter, P.Q.3    Yates, P.O.4
  • 8
    • 0030586660 scopus 로고    scopus 로고
    • Neuronal-based synaptic compensation: A computational study in Alzheimer's disease
    • Horn D, Levy N, Ruppin E (1996) Neuronal-based synaptic compensation: a computational study in Alzheimer's disease. Neural Comput 8:1227-1243
    • (1996) Neural Comput , vol.8 , pp. 1227-1243
    • Horn, D.1    Levy, N.2    Ruppin, E.3
  • 12
    • 0027136017 scopus 로고
    • A new family of neurotransmitter transporters: The high-affinity glutamate transporters
    • Kanai Y, Smith CP, Hediger MA (1993) A new family of neurotransmitter transporters: the high-affinity glutamate transporters. FASEB J 7:1450-1459
    • (1993) FASEB J , vol.7 , pp. 1450-1459
    • Kanai, Y.1    Smith, C.P.2    Hediger, M.A.3
  • 13
    • 0033523480 scopus 로고    scopus 로고
    • Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice
    • Larson J, Lynch G, Games D, Seubert P (1999) Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice. Brain Res 840: 23-35
    • (1999) Brain Res , vol.840 , pp. 23-35
    • Larson, J.1    Lynch, G.2    Games, D.3    Seubert, P.4
  • 15
    • 0036006587 scopus 로고    scopus 로고
    • Endothelin downregulates the glutamate transporter GLAST in cAMP-differentiated astrocytes in vitro
    • Matsuura S, Ikegaya Y, Yamada MK, Nishiyama N, Matsuki N (2002) Endothelin downregulates the glutamate transporter GLAST in cAMP-differentiated astrocytes in vitro. Glia 37:178-182
    • (2002) Glia , vol.37 , pp. 178-182
    • Matsuura, S.1    Ikegaya, Y.2    Yamada, M.K.3    Nishiyama, N.4    Matsuki, N.5
  • 16
    • 0026570528 scopus 로고
    • β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
    • Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, Rydel RE (1992) β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 12:376-389
    • (1992) J Neurosci , vol.12 , pp. 376-389
    • Mattson, M.P.1    Cheng, B.2    Davis, D.3    Bryant, K.4    Lieberburg, I.5    Rydel, R.E.6
  • 18
    • 0028177692 scopus 로고
    • β-Amyloid protein-induced Alzheimer's disease animal model
    • Nitta A, Itoh A, Hasegawa T, Nabeshima T (1994) β-Amyloid protein-induced Alzheimer's disease animal model. Neurosci Lett 170:63-66
    • (1994) Neurosci Lett , vol.170 , pp. 63-66
    • Nitta, A.1    Itoh, A.2    Hasegawa, T.3    Nabeshima, T.4
  • 19
    • 0024399770 scopus 로고
    • Excitatory amino acids and neuropsychiatric disorders
    • Oleny JW (1989) Excitatory amino acids and neuropsychiatric disorders. Biol Psychiatry 26:505-525
    • (1989) Biol Psychiatry , vol.26 , pp. 505-525
    • Oleny, J.W.1
  • 20
    • 0028834147 scopus 로고
    • A neural model of memory impairment in diffuse cerebral atrophy
    • Ruppin E, Reggia JA (1995) A neural model of memory impairment in diffuse cerebral atrophy. Br J Psychiatry 166:19-28
    • (1995) Br J Psychiatry , vol.166 , pp. 19-28
    • Ruppin, E.1    Reggia, J.A.2
  • 22
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe DJ (2002) Alzheimer's disease is a synaptic failure. Science 298:789-791
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 23
    • 0032814135 scopus 로고    scopus 로고
    • Alzheimer's disease and the amyloid β protein: What is the role of amyloid?
    • Small DH, McLean CA (1999) Alzheimer's disease and the amyloid β protein: what is the role of amyloid? J Neurochem 73: 443-449
    • (1999) J Neurochem , vol.73 , pp. 443-449
    • Small, D.H.1    McLean, C.A.2
  • 24
    • 0035433962 scopus 로고    scopus 로고
    • Alzheimer's disease and Aβ toxicity: From top to bottom
    • Small DH, Mok SS, Bornstein JC (2001) Alzheimer's disease and Aβ toxicity: from top to bottom. Nat Rev Neurosci 2:595-598
    • (2001) Nat Rev Neurosci , vol.2 , pp. 595-598
    • Small, D.H.1    Mok, S.S.2    Bornstein, J.C.3
  • 25
    • 0035425615 scopus 로고    scopus 로고
    • Generation of aggregated β-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits
    • Stéphan A, Laroche S, Davis S (2001) Generation of aggregated β-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits. J Neurosci 21:5703-5714
    • (2001) J Neurosci , vol.21 , pp. 5703-5714
    • Stéphan, A.1    Laroche, S.2    Davis, S.3
  • 26
    • 0025987048 scopus 로고
    • Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
    • Terry RD, Masliah E, Salmon DP, Butters N, DeTeresa R, Hill R, Hansen LA, Katzman R (1991) Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30:572-580
    • (1991) Ann Neurol , vol.30 , pp. 572-580
    • Terry, R.D.1    Masliah, E.2    Salmon, D.P.3    Butters, N.4    DeTeresa, R.5    Hill, R.6    Hansen, L.A.7    Katzman, R.8
  • 27
    • 0024990330 scopus 로고
    • Neurotrophic and neurotoxic effects of amyloid β protein: Reversal by tachykinin neuropeptides
    • Yankner BA, Duffy LK, Kirschner DA (1990) Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science 250:279-282
    • (1990) Science , vol.250 , pp. 279-282
    • Yankner, B.A.1    Duffy, L.K.2    Kirschner, D.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.