Frameshifted β-amyloid precursor protein (APP+1) is a secretory protein, and the level of APP+1 in cerebrospinal fluid is linked to Alzheimer pathology

Journal of Biological Chemistry

Volumn 278, Issue 41, 2003, Pages 39637-39643

  Hol, Elly M ^a,c   Van Dijk, Renske ^a   Gerez, Lisya ^b   Sluijs, Jacqueline A ^a   Hobo, Barbara ^a   Tonk, Martijn T ^a   De Haan, Annett ^b   Kamphorst, Wouter ^a   Fischer, David F ^a   Benne, Rob ^b   Van Leeuwen, Fred W ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; NEUROLOGY; PATHOLOGY; PATIENT MONITORING;

PRECURSORS;

PROTEINS;

AMYLOID PRECURSOR PROTEIN; MESSENGER RNA; MUTANT PROTEIN;

ALZHEIMER DISEASE; APP GENE; ARTICLE; BRAAK SCORE; CELL SECRETION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE CLASSIFICATION; FEMALE; FRAMESHIFT MUTATION; GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; NEUROFIBRILLARY TANGLE; NEUROPATHY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN MOTIF; PROTEIN SECRETION; STATISTICAL SIGNIFICANCE;

AGED; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; BLOTTING, WESTERN; BRAIN; CASE-CONTROL STUDIES; CELL LINE; FEMALE; FRAMESHIFT MUTATION; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NEURONS; RADIOIMMUNOASSAY; TRANSFECTION;

ANIMALIA;

EID: 0141925714     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302295200     Document Type: Article

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