Sensitization to mechanical stimulation by inflammatory mediators and by mild burn in canine visceral nociceptors in vitro

Journal of Neurophysiology

Volumn 87, Issue 4, 2002, Pages 2043-2051

  Koda, Hisashi ^a   Mizumura, Kazue ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ; HISTAMINE; PHORBOL DIBUTYRATE; PHORBOL ESTER; PROSTAGLANDIN E2; PROTEIN KINASE C; PROTON;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BURN; CONTROLLED STUDY; DOG; FACILITATION; HYPERALGESIA; INFLAMMATION; MECHANICAL STIMULATION; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; RECEPTIVE FIELD; RECEPTOR SENSITIVITY; SECOND MESSENGER; SENSITIZATION; SINGLE UNIT ACTIVITY;

EID: 0036095985     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00593.2001     Document Type: Article

References (45)

1. Mechanical and heat sensitization of cutaneous nociceptors after peripheral inflammation in the rat
2. Bradykinin and serotonin effects on various types of cutaneous nerve fibres
3. Nervous outflow from the cat's foot during noxious radiant heat stimulation
4. Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli
5. Sensitization of unmyelintaed nociceptive afferents in monkey varies with skin type
6. A capsaicin-receptor homologue with a high threshold for noxious heat
7. Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat
8. Chemosensitivity and sensitization of nociceptive afferents that innervate the hairy skin of monkey
9. 2 modulates the tetrodotoxin-resistant sodium currents in neonatal rat dorsal root ganglion neurones via the cyclic AMP-protein kinase A cascade
10. 2+ dependent process
11. The sensitization of high threshold mechanoreceptors with myelinated axons by repeated heating
12. Visceral polymodal receptors
13. 2-induced sensitization of rat sensory neurons in vitro
14. + current in nociceptors
15. Activation of unmyelinated afferent fibres by mechanical stimuli and inflammation of the urinary bladder in the cat
16. Receptive properties of myelinated primary afferents innervating the inflamed urinary bladder of the cat
17. Pharmacological modulation of the discharge of nociceptive C-fibres
18. The effects of bradykinin and sequence-related analogs on the response properties of cutaneous nociceptors in monkeys
19. Comparison of intradermal and subcutaneous hyperalgesic effects of inflammatory mediators in the rat
20. Hl-receptor-mediated excitation and facilitation of the heat response by histamine in canine visceral polymodal receptors studied in vitro
21. Sensitizing effects of bradykinin on the heat responses of the visceral nociceptor
22. Response properties of polymodal receptors studied using in vitro testis superior spermatic nerve preparations of dogs
23. Chemosensitivity of fine afferents from rat skin in vitro
24. Excitation and sensitization of the heat response induced by a phorbol ester in canine visceral polymodal receptors studied in vitro
25. Pain and hyperalgesia after intradermal injection of bradykinin in humans
26. 4 decreases the mechanical and thermal thresholds of C-fiber nociceptors in the hairy skin of the rat
27. Basic and clinical aspects of visceral hyperalgesia
28. Natural history of nociceptor sensitization - The search for a peripheral mechanism of hyperalgesia
29. Comparison of sensitizing effects of inflammatory mediators on the responses to mechanical and heat stimulations in testicular polymodal receptors in vitro
30. Augmenting effects of cyclic AMP on the heat response of canine testicular polymodal receptors
31. Evidence that protein kinase C activation is involved in excitatory and facilitatory effects of bradykinin on canine visceral nociceptors in vitro
32. Possible contribution of protein kinase C in the effects of histamine on the visceral nociceptor activities in vitro
33. Influence of histamine on the bradykinin response of canine testicular polymodal receptors in vitro
34. The effects of bradykinin agonists and antagonists on visceral polymodal receptor activities
35. 2-induced sensitization of the heat response of canine visceral polymodal receptors in vitro
36. Differences in augmenting effects of various sensitizing agents on heat and bradykinin responses of the testicular polymodal receptor
37. Effects of prostaglandins and other putative chemical intermediaries on the activity of canine testicular polymodal receptors studied in vitro
38. Strong heat stimulation sensitized the heat response as well as the bradykinin response of visceral polymodal receptors
39. Sensitization of articular afferents to mechanical stimuli by bradykinin
40. Effects of temperature on conduction in single vagal and saphenous myelinated nerve fibres of the cat
41. Peripheral neural mechanism of nociception
42. Sensitization of nociceptive cutaneous nerve fibers from the rat's tail by noxious mechanical stimulation
43. 2
44. Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro
45. Mechanosensitive pelvic nerve afferent fibers innervating the colon of the rat are polymodal in character