Probing residual interactions in unfolded protein states using NMR spin relaxation techniques: An application to Δ131Δ

Journal of the American Chemical Society

Volumn 125, Issue 39, 2003, Pages 11988-11992

  Choy, Wing Yiu ^a   Kay, Lewis E ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROPHOBIC CONTACTS;

HYDROPHOBICITY; NUCLEAR MAGNETIC RESONANCE; PH EFFECTS; RELAXATION OSCILLATORS;

PROTEINS;

BACTERIAL PROTEIN; NUCLEASE; STAPHYLOCOCCAL NUCLEASE; UNCLASSIFIED DRUG;

ARTICLE; DEUTERON NUCLEAR MAGNETIC RESONANCE; DYNAMICS; ELECTRICITY; HYDROPHOBICITY; MOLECULAR PROBE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE SPIN RELAXATION TECHNIQUE; PH; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION;

DEUTERIUM; ELECTROSTATICS; HYDROGEN-ION CONCENTRATION; HYDROPHOBICITY; MICROCOCCAL NUCLEASE; NITROGEN ISOTOPES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN FOLDING; THERMODYNAMICS;

EID: 0141843568     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja035705q     Document Type: Article

References (27)

1. Dunker, A. K.; Lawson, J. D.; Brown, C. J.; Williams, R. M.; Romero, P.; Oh, J. S.; Oldfield, C. J.; Campen, A. M.; Ratliff, C. M.; Hipps, K. W.; Ausio, J.; Nissen, M. S.; Reeves, R.; Kang, C. H.; Kissinger, C. R.; Bailey, R. W.; Griswold, M. D.; Chiu, W.; Garber, E. C.; Obradovic, Z. J. Mol. Graph. Model. 2001, 19, 26-59.
2. Kriwacki, R. W.; Hengst, L.; Tennant, L.; Reed, S. I.; Wright, P. E. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 11504-11509.
3. Campbell, K. M.; Terrell, A. R.; Laybourn, P. J.; Lumb, K. J. Biochemistry 2000, 39, 2708-2713.
4. Nash, P.; Tang, X.; Orlicky, S.; Chen, Q.; Gertler, F. B.; Mendenhall, M. D.; Sicheri, F.; Pawson, T.; Tyers, M. Nature 2001, 414, 514-521.
5. Shortle, D.; Wang, Y.; Gillespie, J. R.; Wrabl, J. O. Protein Sci. 1996, 5, 991-1000.
6. Dyson, H. J.; Wright, P. E. Nat. Struct. Biol. 1998, supplement, 499-503.
7. Farrow, N. A.; Zhang, O. W.; Forman-Kay, J. D.; Kay, L. E. Biochemistry 1995, 34, 868-878.
8. Muhandiram, D. R.; Johnson, P. E.; Yang, D.; Zhang, O.; McIntosh, L. P.; Kay, L. E. J. Biomol. NMR 1997, 10, 283-288.
9. Choy, W. Y.; Shortle, D.; Kay, L. E. J. Am. Chem. Soc. 2003, 125, 1748-1758.
10. Alexandrescu, A. T.; Shortle, D. J. Mol. Biol. 1994, 242, 527-546.
11. Gillespie, J. R.; Shortle, D. J. Mol. Biol. 1997, 268, 158-169.
12. Gillespie, J. R.; Shortle, D. J. Mol. Biol. 1997, 268, 170-184.
13. Ackerman, M. S.; Shortle, D. Biochemistry 2002, 41, 3089-3095.
14. Lipari, G.; Szabo, A. J. Am. Chem. Soc. 1982, 104, 4546-4559.
15. Lipari, G.; Szabo, A. J. Am. Chem. Soc. 1982, 104, 4559-4570.
16. Skrynnikov, N. R.; Millet, O.; Kay, L. E. J. Am. Chem. Soc. 2002, 124, 6449-6460.
17. Choy, W. Y.; Kay, L. E. J. Biomol. NMR 2003, 25, 325-333.
18. Mittermaier, A.; Kay, L. E.; Forman-Kay, J. D. J. Biomol. NMR 1999, 13, 181-185.
19. Perez, C.; Lohr, F.; Ruterjans, H.; Schmidt, J. M. J. Am. Chem. Soc. 2001, 123, 7081-7093.
20. Clore, G. M.; Szabo, A.; Bax, A.; Kay, L. E.; Driscoll, P. C.; Gronenborn, A. M. J. Am. Chem. Soc. 1990, 112, 4989-4991.
21. Whitten, S. T.; Garcia-Moreno, E. B. Biochemistry 2000, 39, 14292-14304.
22. Zhou, H. X. Biophys. J. 2003, 83, 2981-2986.
23. Ohnishi, S.; Shortle, D. Protein Sci. 2003, 12, 1530-1537.
24. Flanagan, J. M.; Kataoka, M.; Shortle, D.; Engelman, D. M. Proc. Natl. Acad. Sci. U.S.A. 1992, 89, 748-752.
25. Klein-Seetharaman, J.; Oikawa, M.; Grimshaw, S. B.; Wirmer, J.; Duchardt, E.; Ueda, T.; Imoto, T.; Smith, L. J.; Dobson, C. M.; Schwalbe, H. Science 2002, 295, 1719-1722.
26. Schwarzinger, S.; Wright, P. E.; Dyson, H. J. Biochemistry 2002, 41, 12681-12686.
27. Kyte, J.; Doolittle, R. F. J. Mol. Biol. 1982, 157, 105-132.