Hematopoietic expression of HOXB4 is regulated in normal and leukemic stem cells through transcriptional activation of the HOXB4 promoter by upstream stimulating factor (USF)-1 and USF-2

Journal of Experimental Medicine

Volumn 192, Issue 10, 2000, Pages 1479-1490

  Giannola, Diane M ^a   Shlomchik, Warren D ^b   Jegathesan, Mithila ^a   Liebowitz, David ^a   Abrams, Charles S ^a   Kadesch, Tom ^a   Dancis, Andrew ^a   Emerson, Stephen G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Homeobox genes; Self renewal; Stem cells; Transcription; USF

Indexed keywords

FLT3 LIGAND; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; STEM CELL FACTOR; THROMBOPOIETIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UPSTREAM STIMULATORY FACTOR 1; UPSTREAM STIMULATORY FACTOR 2;

ARTICLE; BONE MARROW; CELL DIFFERENTIATION; CELL RENEWAL; CELL STRAIN K 562; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GENETIC REGULATION; HEMATOPOIETIC STEM CELL; HOMEOBOX; HOMEOSTASIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION;

BASE SEQUENCE; BONE MARROW CELLS; DNA-BINDING PROTEINS; GENOMIC LIBRARY; HEMATOPOIETIC STEM CELLS; HOMEODOMAIN PROTEINS; HUMANS; K562 CELLS; LEUKEMIA, MYELOID, CHRONIC; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RAS PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; UPSTREAM STIMULATORY FACTORS;

EID: 0034694023     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.192.10.1479     Document Type: Article

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