메뉴 건너뛰기




Volumn 4, Issue 2, 2003, Pages 104-109

Genetic control of visceral leishmaniasis in a Sudanese population: Candidate gene testing indicates a linkage to the NRAMP1 region

Author keywords

Human genetics; NRAMP1; Visceral leishmaniasis

Indexed keywords

CHROMOSOME 12Q; CHROMOSOME 2Q; CHROMOSOME 5Q; CHROMOSOME 6P; CHROMOSOME 6Q; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; EPIDEMIC; EVIDENCE BASED MEDICINE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENE LOCUS; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC MARKER; GENETIC POLYMORPHISM; GENETIC REGULATION; GENETIC VARIABILITY; HEREDITY; HUMAN; INFECTION CONTROL; INFECTION SENSITIVITY; LEISHMANIA DONOVANI; LINKAGE ANALYSIS; MOUSE; NONHUMAN; PARASITOSIS; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; SUDAN; VISCERAL LEISHMANIASIS; ADOLESCENT; ADULT; ARTICLE; CHILD; GENETIC PREDISPOSITION; GENETICS; MALE;

EID: 0141799481     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6363927     Document Type: Review
Times cited : (76)

References (47)
  • 1
    • 0030880058 scopus 로고    scopus 로고
    • The impact of host genetics on susceptibility to human infectious diseases
    • Abel L, Dessein AJ. The impact of host genetics on susceptibility to human infectious diseases. Curr Opin Immunol 1997; 9: 509-516.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 509-516
    • Abel, L.1    Dessein, A.J.2
  • 3
    • 0028568490 scopus 로고
    • Endemic kala-azar in eastern Sudan: A longitudinal study on the incidence of clinical and subclinical infection and post-kala-azar dermal leishmaniasis
    • Zijlstra EE, el-Hassan AM, Ismael A, Ghalib HW. Endemic kala-azar in eastern Sudan: a longitudinal study on the incidence of clinical and subclinical infection and post-kala-azar dermal leishmaniasis. Am J Trop Med Hyg 1994; 51: 826-836.
    • (1994) Am. J. Trop. Med. Hyg. , vol.51 , pp. 826-836
    • Zijlstra, E.E.1    el-Hassan, A.M.2    Ismael, A.3    Ghalib, H.W.4
  • 4
    • 0035348374 scopus 로고    scopus 로고
    • The increase in risk factors for leishmaniasis worldwide
    • Desjeux P. The increase in risk factors for leishmaniasis worldwide. Trans R Soc Trop Med Hyg 2001; 95: 239-243.
    • (2001) Trans. R. Soc. Trop. Med. Hyg. , vol.95 , pp. 239-243
    • Desjeux, P.1
  • 5
    • 0029892549 scopus 로고    scopus 로고
    • Genetic susceptibility to leishmanial infections: Studies in mice and man
    • Blackwell JM. Genetic susceptibility to leishmanial infections: studies in mice and man. Parasitology 1996; 112: S67-S74.
    • (1996) Parasitology , vol.112
    • Blackwell, J.M.1
  • 6
    • 0029861329 scopus 로고    scopus 로고
    • Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses
    • Gorham JD, Guler ML, Steen RG et al. Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses. Proc Natl Acad Sci USA 1996; 93: 12 467-12 472.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 12467-12472
    • Gorham, J.D.1    Guler, M.L.2    Steen, R.G.3
  • 7
    • 0029092312 scopus 로고
    • The Ity/Lsh/Bcg locus: Natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene
    • Vidal S, Tremblay ML, Govoni G et al. The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. J Exp Med 1995; 182: 655-666.
    • (1995) J. Exp. Med. , vol.182 , pp. 655-666
    • Vidal, S.1    Tremblay, M.L.2    Govoni, G.3
  • 8
    • 0017238362 scopus 로고
    • Genetics of resistance to infection with Salmonella typhimurium in mice
    • Plant J, Glynn AA. Genetics of resistance to infection with Salmonella typhimurium in mice. J Infect Dis 1976; 133: 72-78.
    • (1976) J. Infect. Dis. , vol.133 , pp. 72-78
    • Plant, J.1    Glynn, A.A.2
  • 9
    • 0019835032 scopus 로고
    • Genetic control of natural resistance to Mycobacterium bovis (BCG) in mice
    • Gros P, Skamene E, Forget A. Genetic control of natural resistance to Mycobacterium bovis (BCG) in mice. J Immunol 1981; 127: 2417-2421.
    • (1981) J. Immunol. , vol.127 , pp. 2417-2421
    • Gros, P.1    Skamene, E.2    Forget, A.3
  • 10
    • 0021341947 scopus 로고
    • Regulation of resistance to leprosy by chromosome 1 locus in the mouse
    • Skamene E, Gros P, Forget A, Patel PJ, Nesbitt MN. Regulation of resistance to leprosy by chromosome 1 locus in the mouse. Immunogenetics 1984; 19: 117-124.
    • (1984) Immunogenetics , vol.19 , pp. 117-124
    • Skamene, E.1    Gros, P.2    Forget, A.3    Patel, P.J.4    Nesbitt, M.N.5
  • 11
    • 0018891082 scopus 로고
    • Influence of H-2 complex on acquired resistance to Leishmania donovani infection in mice
    • Blackwell J, Freeman J, Bradley D. Influence of H-2 complex on acquired resistance to Leishmania donovani infection in mice. Nature 1980; 283: 72-74.
    • (1980) Nature , vol.283 , pp. 72-74
    • Blackwell, J.1    Freeman, J.2    Bradley, D.3
  • 12
    • 0029093323 scopus 로고
    • Recent observations on the epidemiology of kala-azar in the eastern and central states of the Sudan
    • el-Hassan AM, Zijlstra EE, Ismael A, Ghalib HW. Recent observations on the epidemiology of kala-azar in the eastern and central states of the Sudan. Trop Geogr Med 1995; 47: 151-156.
    • (1995) Trop. Geogr. Med. , vol.47 , pp. 151-156
    • el-Hassan, A.M.1    Zijlstra, E.E.2    Ismael, A.3    Ghalib, H.W.4
  • 13
    • 0033389690 scopus 로고    scopus 로고
    • Kala-azar in a high transmission focus: An ethnic and geographic dimension
    • Ibrahim ME, Lambson B, Yousif AO et al. Kala-azar in a high transmission focus: an ethnic and geographic dimension. Am J Trop Med Hyg 1999; 61: 941-944.
    • (1999) Am. J. Trop. Med. Hyg. , vol.61 , pp. 941-944
    • Ibrahim, M.E.1    Lambson, B.2    Yousif, A.O.3
  • 15
    • 0030882272 scopus 로고    scopus 로고
    • Evidence for a major gene controlling susceptibility to tegumentary leishmaniasis in a recently exposed Bolivian population
    • Alcais A, Abel L, David C et al. Evidence for a major gene controlling susceptibility to tegumentary leishmaniasis in a recently exposed Bolivian population. Am J Hum Genet 1997; 61: 968-979.
    • (1997) Am. J. Hum. Genet. , vol.61 , pp. 968-979
    • Alcais, A.1    Abel, L.2    David, C.3
  • 16
    • 0028832278 scopus 로고
    • Polymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis
    • Cabrera M, Shaw MA, Sharples C et al. Polymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis. J Exp Med 1995; 182: 1259-1264.
    • (1995) J. Exp. Med. , vol.182 , pp. 1259-1264
    • Cabrera, M.1    Shaw, M.A.2    Sharples, C.3
  • 18
    • 18744387204 scopus 로고    scopus 로고
    • The interplay between environmental and host factors during an outbreak of visceral leishmaniasis in eastern Sudan
    • (in press)
    • Bucheton B, Kheir MM, El-Safi SH et al. The interplay between environmental and host factors during an outbreak of visceral leishmaniasis in eastern Sudan. Microbes Infect 2002; (in press).
    • (2002) Microbes. Infect.
    • Bucheton, B.1    Kheir, M.M.2    El-Safi, S.H.3
  • 19
    • 0029842548 scopus 로고    scopus 로고
    • Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33
    • Marquet S, Abel L, Hillaire D et al. Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33. Nat Genet 1996; 14: 181-184.
    • (1996) Nat. Genet. , vol.14 , pp. 181-184
    • Marquet, S.1    Abel, L.2    Hillaire, D.3
  • 20
    • 0031779808 scopus 로고    scopus 로고
    • Linkage analysis of blood Plasmodium falciparum levels: Interest of the 5q31-q33 chromosome region
    • Garcia A, Marquet S, Bucheton B et al. Linkage analysis of blood Plasmodium falciparum levels: interest of the 5q31-q33 chromosome region. Am J Trop Med Hyg 1998; 58: 705-709.
    • (1998) Am. J. Trop. Med. Hyg. , vol.58 , pp. 705-709
    • Garcia, A.1    Marquet, S.2    Bucheton, B.3
  • 21
    • 0032231356 scopus 로고    scopus 로고
    • Malaria in humans: Plasmodium falciparum blood infection levels are linked to chromosome 5q31-q33
    • Rihet P, Traore Y, Abel L et al. Malaria in humans: Plasmodium falciparum blood infection levels are linked to chromosome 5q31-q33. Am J Hum Genet 1998; 63: 498-505.
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 498-505
    • Rihet, P.1    Traore, Y.2    Abel, L.3
  • 22
    • 0027957091 scopus 로고
    • Evidence for a locus regulating total serum IgE levels mapping to chromosome 5
    • Meyers DA, Postma DS, Panhuysen CI et al. Evidence for a locus regulating total serum IgE levels mapping to chromosome 5. Genomics 1994; 23: 464-470.
    • (1994) Genomics , vol.23 , pp. 464-470
    • Meyers, D.A.1    Postma, D.S.2    Panhuysen, C.I.3
  • 23
    • 0028230946 scopus 로고
    • Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations
    • Marsh DG, Neely JD, Breazeale DR et al. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 1994; 264: 1152-1156.
    • (1994) Science , vol.264 , pp. 1152-1156
    • Marsh, D.G.1    Neely, J.D.2    Breazeale, D.R.3
  • 24
    • 0025768733 scopus 로고
    • Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis
    • Heinzel FP, Sadick MD, Mutha SS, Locksley RM. Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis. Proc Natl Acad Sci USA 1991; 88: 7011-7015.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7011-7015
    • Heinzel, F.P.1    Sadick, M.D.2    Mutha, S.S.3    Locksley, R.M.4
  • 25
    • 0036219062 scopus 로고    scopus 로고
    • Genetic dissection of immunity to mycobacteria: The human model
    • Casanova JL, Abel L. Genetic dissection of immunity to mycobacteria: the human model. Annu Rev Immunol 2002; 20: 581-620.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 581-620
    • Casanova, J.L.1    Abel, L.2
  • 26
    • 0032935301 scopus 로고    scopus 로고
    • Evidence for a functional repeat polymorphism in the promoter of the human NRAMP1 gene that correlates with autoinumme versus infectious disease susceptibility
    • Searle S, Blackwell JM. Evidence for a functional repeat polymorphism in the promoter of the human NRAMP1 gene that correlates with autoinumme versus infectious disease susceptibility. J Med Genet 1999; 36: 295-299.
    • (1999) J. Med. Genet. , vol.36 , pp. 295-299
    • Searle, S.1    Blackwell, J.M.2
  • 27
    • 0034945912 scopus 로고    scopus 로고
    • Nramp1 modulates iron homoeostasis in vivo and in vitro: Evidence for a role in cellular iron release involving de-acidification of intracellular vesicles
    • Biggs TE, Baker ST, Botham MS et al. Nramp1 modulates iron homoeostasis in vivo and in vitro: evidence for a role in cellular iron release involving de-acidification of intracellular vesicles. Eur J Immunol 2001; 31: 2060-2070.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 2060-2070
    • Biggs, T.E.1    Baker, S.T.2    Botham, M.S.3
  • 28
    • 0031033088 scopus 로고    scopus 로고
    • Natural resistance to infection with intracellular pathogens: The Nramp1 protein is recruited to the membrane of the phagosome
    • Gruenheid S, Pinner E, Desjardins M, Gros P. Natural resistance to infection with intracellular pathogens: the Nramp1 protein is recruited to the membrane of the phagosome. J Exp Med 1997; 185: 717-730.
    • (1997) J. Exp. Med. , vol.185 , pp. 717-730
    • Gruenheid, S.1    Pinner, E.2    Desjardins, M.3    Gros, P.4
  • 29
    • 0035209779 scopus 로고    scopus 로고
    • SLC11A1 (formerly NRAMP1) and disease resistance
    • Blackwell JM, Goswami T, Evans.CA et al. SLC11A1 (formerly NRAMP1) and disease resistance. Cell Microbiol 2001; 3: 773-784.
    • (2001) Cell Microbiol. , vol.3 , pp. 773-784
    • Blackwell, J.M.1    Goswami, T.2    Evans, C.A.3
  • 30
    • 0032485353 scopus 로고    scopus 로고
    • Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans
    • Bellamy R, Ruwende C, Corrah T et al. Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans. N Engl J Med 1998; 338: 640-644.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 640-644
    • Bellamy, R.1    Ruwende, C.2    Corrah, T.3
  • 31
    • 0033853675 scopus 로고    scopus 로고
    • Linkage of tuberculosis to chromosome 2q35 loci, including NRAMP1, in a large aboriginal Canadian family
    • Greenwood CM, Fujiwara TM, Boothroyd LJ et al. Linkage of tuberculosis to chromosome 2q35 loci, including NRAMP1, in a large aboriginal Canadian family. Am J Hum Genet 2000; 67: 405-416.
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 405-416
    • Greenwood, C.M.1    Fujiwara, T.M.2    Boothroyd, L.J.3
  • 32
    • 0031975989 scopus 로고    scopus 로고
    • Susceptibility to leprosy is linked to the human NRAMP1 gene
    • Abel L, Sanchez FO, Oberti J et al. Susceptibility to leprosy is linked to the human NRAMP1 gene. J Infect Dis 1998; 177: 133-145.
    • (1998) J. Infect. Dis. , vol.177 , pp. 133-145
    • Abel, L.1    Sanchez, F.O.2    Oberti, J.3
  • 33
    • 0032723967 scopus 로고    scopus 로고
    • Variants of the human NRAMP1 gene and altered human immunodeficiency virus infection susceptibility
    • Marquet S, Sanchez FO, Arias M et al. Variants of the human NRAMP1 gene and altered human immunodeficiency virus infection susceptibility. J Infect Dis 1999; 180: 1521-1515.
    • (1999) J. Infect. Dis. , vol.180 , pp. 1515-1521
    • Marquet, S.1    Sanchez, F.O.2    Arias, M.3
  • 34
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996; 273: 1516-1517.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 36
    • 0031970784 scopus 로고    scopus 로고
    • A causative relationship between mutant IFNgR1 alleles, and impaired cellular response to IFNgamma in a compound heterozygous child
    • Altare F, Jouanguy E, Lamhamedi-Cherradi S et al. A causative relationship between mutant IFNgR1 alleles, and impaired cellular response to IFNgamma in a compound heterozygous child. Am J Hum Genet 1998; 62: 723-726.
    • (1998) Am. J. Hum. Genet. , vol.62 , pp. 723-726
    • Altare, F.1    Jouanguy, E.2    Lamhamedi-Cherradi, S.3
  • 37
    • 0019971912 scopus 로고
    • Structure of the human immune interferon gene
    • Gray PW, Goeddel DV. Structure of the human immune interferon gene. Nature 1982; 298: 859-863.
    • (1982) Nature , vol.298 , pp. 859-863
    • Gray, P.W.1    Goeddel, D.V.2
  • 38
    • 0028915859 scopus 로고
    • Identification of polymorphisms and sequence variants in the human homologue of the mouse natural resistance-associated macrophage protein gene
    • Liu J, Fujiwara TM, Buu NT et al. Identification of polymorphisms and sequence variants in the human homologue of the mouse natural resistance-associated macrophage protein gene. Am J Hum Genet 1995; 56: 845-853.
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 845-853
    • Liu, J.1    Fujiwara, T.M.2    Buu, N.T.3
  • 40
    • 0031815057 scopus 로고    scopus 로고
    • Comparison of four sib-pair linkage methods for analyzing sibships with more than two affecteds: Interest of the binomial maximum likelihood approach
    • Abel L, Alcais A, Mallet A. Comparison of four sib-pair linkage methods for analyzing sibships with more than two affecteds: interest of the binomial maximum likelihood approach. Genet Epidemiol 1998; 15: 371-390.
    • (1998) Genet. Epidemiol. , vol.15 , pp. 371-390
    • Abel, L.1    Alcais, A.2    Mallet, A.3
  • 41
    • 1642633542 scopus 로고    scopus 로고
    • Robustness and power of the maximum-likelihood-binomial and maximum-likelihood-score methods, in multipoint linkage analysis of affected-sibship data
    • Abel L, Muller-Myhsok B. Robustness and power of the maximum-likelihood-binomial and maximum-likelihood-score methods, in multipoint linkage analysis of affected-sibship data. Am J Hum Genet 1998; 63: 638-647.
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 638-647
    • Abel, L.1    Muller-Myhsok, B.2
  • 42
    • 0029886532 scopus 로고    scopus 로고
    • Parametric and nonparametric linkage analysis: A unified multipoint approach
    • Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES. Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 1996; 58: 1347-1363.
    • (1996) Am. J. Hum. Genet. , vol.58 , pp. 1347-1363
    • Kruglyak, L.1    Daly, M.J.2    Reeve-Daly, M.P.3    Lander, E.S.4
  • 43
    • 0027377799 scopus 로고
    • Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
    • Spielman RS, McGinnis RE, Ewens WJ. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 1993; 52: 506-516.
    • (1993) Am. J. Hum. Genet. , vol.52 , pp. 506-516
    • Spielman, R.S.1    McGinnis, R.E.2    Ewens, W.J.3
  • 44
    • 0033364961 scopus 로고    scopus 로고
    • The transmission/disequilibrium test and parental-genotype reconstruction: The reconstruction-combined transmission/disequilibrium test
    • Knapp M. The transmission/disequilibrium test and parental-genotype reconstruction: the reconstruction-combined transmission/disequilibrium test. Am J Hum Genet 1999; 64: 861-870.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 861-870
    • Knapp, M.1
  • 45
    • 0031912715 scopus 로고    scopus 로고
    • A sibship test for linkage in the presence of association: The sib transmission/disequilibrium test
    • Spielman RS, Ewens WJ. A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. Am J Hum Genet 1998; 62: 450-458.
    • (1998) Am. J. Hum. Genet. , vol.62 , pp. 450-458
    • Spielman, R.S.1    Ewens, W.J.2
  • 46
    • 0035055544 scopus 로고    scopus 로고
    • The family based association test method: Strategies for studying general genotype-phenotype associations
    • Horvath S, Xu X, Laird NM. The family based association test method: strategies for studying general genotype-phenotype associations. Eur J Hum Genet 2001; 9: 301-306.
    • (2001) Eur. J. Hum. Genet. , vol.9 , pp. 301-306
    • Horvath, S.1    Xu, X.2    Laird, N.M.3
  • 47
    • 0033652887 scopus 로고    scopus 로고
    • Family-based tests of association in the presence of linkage
    • Lake SL, Blacker D, Laird NM. Family-based tests of association in the presence of linkage. Am J Hum Genet 2000; 67: 1515-1525.
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 1515-1525
    • Lake, S.L.1    Blacker, D.2    Laird, N.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.