Evidence for a major gene controlling susceptibility to tegumentary Leishmaniasis in a recently exposed Bolivian population

American Journal of Human Genetics

Volumn 61, Issue 4, 1997, Pages 968-979

  Alcais A ^a   Abel, L ^a   David, C ^b   Torrez, M E ^b   Flandre, P ^c   Dedet, J P ^d  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b Instituto Boliviano de Biologia de Altura   (Bolivia)

^c INSERM   (France)

^d UNIV MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AGE; ARTICLE; BOLIVIA; DISEASE PREDISPOSITION; ENVIRONMENTAL FACTOR; GENE; GENETIC HETEROGENEITY; GENOTYPE; HEREDITY; HUMAN; LEISHMANIA BRAZILIENSIS; LEISHMANIASIS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PSYCHODIDAE;

LEISHMANIA BRAZILIENSIS; PSYCHODIDAE;

EID: 0030882272     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/514882     Document Type: Article

References (45)

1. Abel L, Bonney GE (1990) A time-dependent logistic hazard function for modeling variable age of onset in analysis of familial disease. Genet Epidemiol 7:391-407
2. Akaike H (1974) A new look at the statistical model identification. IEEE Trans Automatic Control AC 19:716-723
3. Alcaïs A, Abel L, David C, Torres ME, Flandre P, Dedet JP (1997) Risk factors for onset of cutaneous and mucocutaneous leishmaniasis in Bolivia. Am J Trop Med Hyg 57:79-84
4. Antoine JC (1995) Biologie des interactions macrophages: leishmania. Pathol Biol 43:215-223
5. Barbier D, Demenais F, Lefait JF, David B, Blanc M, Hors J, Feingold N (1987) Susceptibility to human cutaneous leishmaniasis and HLA, Gm, Km markers. Tissue Antigens 30: 63-67
6. Blackwell JM, Freeman J, Bradley DJ (1980) Influence of H-2 complex on acquired resistance to Leishmania donovani. Nature 283:72-74
7. Blackwell JM, Roberts M, Alexandre J (1985) Response of BALB/c mice to leishmanial infection. Curr Top Microbiol Immunol 122:227-232
8. Bonney GE (1986) Regressive logistic model for familial disease and other binary traits. Biometrics 42:611-625
9. Bradley DJ (1974) Genetic control of natural resistance to Leishmania donovani. Nature 250:353-354
10. Bradley DJ, Taylor BA, Blackwell J, Evans EP, Freeman J (1979) Regulation of Leishmania population with the host. I. The variable course of Leishmania donovani infection in mice. Clin Exp Immunol 37:7-14
11. Cabello PH, Dias Lima AM, Azevedo ES, Krieger H (1995) Familial aggregation of Leishmania chagasi infection in northeastern Brazil. Am J Trop Med Hyg 52:364-365
12. Cabrera M, Shaw MA, Sharpies C, Hazel W, Castes M, Convit J, Blackwell JM (1995) Polymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis. J Exp Med 182:1259-1264
13. Cellier M, Govoni G, Vidal S, Kwan T, Groulx N, Liu J, Sanchez F (1994) Human natural resistance-associated macrophage protein:cDNA cloning, chromosomal mapping, genomic organization, and tissue specific expression. J Exp Med 180:1741-1752
14. Chang KP, Dwyer DM (1978) Leishmania donovani: hamster macrophage interactions in vitro:cell entry, intracellular survival, and multiplication of amastigotes. J Exp Med 147: 515-530
15. David C, Dimier-David L, Vargas F, Torrez M, Dedet JP (1993) Fifteen years of cutaneous and mucocutaneous leishmaniasis in Bolivia: a retrospective study. Trans R Soc Trop Med Hyg 87:7-9
16. Davies CR, Llanos-Cuentas EA, Pyke SDM, Dye C (1995) Cutaneous leishmaniasis in Peruvian Andes: an epidemiological study of infection and immunity. Epidemiol Infect 114:297-318
17. Dedet JP, Melogno R, Cardenas F, Valda L, David C, Fernandez V, Torrez ME, et al (1995) Rural campaign to diagnose and treat mucocutaneous leishmaniasis in Bolivia. Bull World Health Organ 73:339-345
18. Demenais FM (1991) Regressive logistic models for familial diseases: a formulation assuming an underlying liability model. Am J Hum Genet 49:773-785
19. Demenais F, Abel L (1989) Robustness of the unified model to shared environmental effects in the analysis of dichotomous traits. Genet Epidemiol 6:229-234
20. Demenais F, Laing A, Bonney GE (1992) Numerical comparisons of two formulations of the logistic regressive models with the mixed model in segregation analysis of discret traits. Genet Epidemiol 9:419-435
21. Demenais F, Lathrop M, Lalouel JM (1986) Robustness and power of the unified model in the analysis of quantitative measurements. Am J Hum Genet 38:228-234
22. Elston RC, Bailey-Wilson JE, Bonney GE, Keats BI, Wilson AF (1986) SAGE - a package of computer programs to perform statistical analysis in genetic epidemiology. Paper presented at the Seventh International Congress on Human Genetics, Berlin, September 22-26
23. Elston RC, Sobel E (1979) Sampling considerations in the gathering and analysis of pedigree data. Am J Hum Genet 31:62-69
24. Elston RC, Stewart (1971). A general model for the genetic analysis of pedigree data. Hum Hered 21:523-542
25. Fine PEM (1981) Immunogenetics of susceptibility to leprosy, tuberculosis, and leishmaniasis: an epidemiological perspective. Int J Lepr Other Mycobact Dis 49:437-454
26. H1 cell development. Science 271:984-990
27. Howard JG, Hale C, Liew FY (1980) Immunological regulation of experimental cutaneous leishmaniasis. I. Immunogenetic aspects of susceptibility to Leishmania tropica in mice. Parasitol Immunol 2:303-314
28. Jones TC, Johnson WD, Barreto AC, Lago E, Badaro R, Cerf B, Reed SG, et al (1987) Epidemiology of American leishmaniasis due to Leishmania braziliensis braziliensis. J Infect Dis 156:73-83
29. Kaye PM, Patel NK, Blackwell JM (1988) Acquisition of cell-mediated immunity to Leishmania. Immunology 65: 17-22
30. Lainson R, Shaw JJ (1987) Evolution, classification and geographical distribution. In: Peters W, Killick Kendrick R (eds) The leishmaniases in biology and medicine. Academic Press, New-York, pp 1-120
31. Lara ML, Larysse Z, Scorza JV, Garcia E, Stoikow Z, Granados J, Bias W (1991) Immunogenetics of human american cutaneous leishmaniasis: study of HLA haplotypes in 24 families from Venezuela. Hum Immunol 30:129-136
32. Llanos-Cuentas EA, Marsden PD, Lago EL, Barreto AC, Cuba CA, Johnson WD Jr (1984) Human mucocutaneous leishmaniasis in Très Braços, Bahia-Brazil: an area of Leishmania braziliensis braziliensis transmission. II. Cutaneous disease: presentation and evolution. Rev Soc Bras Med Trop 17: 169-177
33. Marquet S, Abel L, Hillaire D, Dessein H, Kalil J, Feingold J, Weissenbach J, et al (1996) Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33. Nat Genet 14:181-184
34. Marsden PD (1986) Mucosal leishmaniasis. Trans R Soc Trop Med Hyg 80:859-876
35. Petz-Erler ML, Belich MP, Queiroz-Telles F (1991) Association of mucosal leishmaniasis with HLA. Hum Immunol 32: 254-260
36. Pirmez C, Yamamura M, Uyemura K, Paes-Oliviera M, Concelcao Silva F, Modlin RL (1993) Cytokines patterns in the pathogenesis of human leishmaniasis. J Clin Invest 91: 1390-1395
37. Revello S, Dimier-David L, David C, Lyevre P, Camacho C, Dedet JP (1992) Isoenzyme characterization of Leishmania braziliensis braziliensis isolates obtained from Bolivian and Peruvian patients. Trans R Soc Trop Med Hyg 86:388-391
38. Rioux JA, Lanotte G, Serres E, Pratlong F, Bastien P, Perriere J (1990) Taxonomy of Leishmania: use of isoenzymes: suggestions for a new classification. Ann Parasitol Hum Comp 65:111-125
39. Roberts M, Alexander J, Blackwell JM (1989) Influence of Lsh, H-2, and H-11 linked gene on visceralization and metastasis associated with Leishmania mexicana infection in mice. Infect Immun 57:875-881
40. Roberts M, Mock BA, Blackwell JM (1993) Mapping of genes controlling Leishmania major infection in CXS recombinant inbred mice. Eur J Immunogenet 20:349-362
41. Schurr E, Skamene E, Forget A, Gros P (1989) Linkage analysis of the Bcg gene on mouse chromosome 1: identification of a tightly linked marker. J Immunol 142:4507-4513
42. Shaw M-A, Davies CR, Llanos-Cuentas EA, Collins A (1995) Human genetic susceptibility and infection with Leishmania peruviana. Am J Hum Genet 57:1159-1168
43. Skamene E, Gros P, Forget A, Kongshavn PAL, St Charles C, Baylor BA (1982) Genetic regulation of resistance to intracellular pathogens. Nature 297:506-509
44. Vidal SM, Malo D, Vogan K, Skamene E, Gros P (1993) Natural resistance to infection with intracellular parasites: isolation of a candidate for bcg. Cell 73:469-485
45. Walton BC, Valverde L (1979) Racial differences in espundia. Ann Trop Med Parasitol 73:23-29