A high-throughput, nonisotopic, competitive binding assay for kinases using nonselective inhibitor probes (ED-NSIP™)

Journal of Biomolecular Screening

Volumn 7, Issue 6, 2002, Pages 507-514

  Vainshtein, Inna ^a,b   Silveria, Scott ^a,b   Kaul, Poonam ^a,b   Rouhani, Riaz ^a,b   Eglen, Richard M ^a   Wang, John ^a,b  

^a DiscoveRx Corporation   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA GALACTOSIDASE; DIMETHYL SULFOXIDE; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 ALPHA; ISOTOPE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE; RECOMBINANT PROTEIN; STAUROSPORINE;

ANIMAL; ARTICLE; BINDING COMPETITION; BINDING SITE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG ANTAGONISM; DRUG SCREENING; GENETICS; HUMAN; METABOLISM; METHODOLOGY; MOLECULAR BIOLOGY; REPRODUCIBILITY;

ADENOSINE TRIPHOSPHATE; ANIMALS; BETA-GALACTOSIDASE; BINDING SITES; BINDING, COMPETITIVE; COMBINATORIAL CHEMISTRY TECHNIQUES; DIMETHYL SULFOXIDE; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; ISOTOPES; MOLECULAR BIOLOGY; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; STAUROSPORINE;

EID: 0141768651     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057102238624     Document Type: Article

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