Membrane targeting of p115 phosphorylation mutants and their effects on Golgi integrity and secretory traffic

European Journal of Cell Biology

Volumn 82, Issue 8, 2003, Pages 411-420

  Brandon, Elizabeth ^a   Gao, Yasheng ^a   Garcia Mata, Rafael ^a   Alvarez, Cecilia ^a   Sztul, Elizabeth ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Golgi; Membrane targeting; Mutants; p115; Phosphorylation; Secretory traffic

Indexed keywords

CARRIER PROTEIN; GIANTIN; MATRIX PROTEIN; MEMBRANE PROTEIN; MUTANT PROTEIN; PHOSPHOPROTEIN; PROTEIN GM130; PROTEIN P115; SERINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CELL STRUCTURE; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN TARGETING; PROTEIN TRANSPORT;

EID: 0141717207     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1078/0171-9335-00327     Document Type: Article

References (49)

1. Allan, B., Moyer, B., Balch, W. (2000): Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion. Science 289, 444-448.
2. Alvarez, C., Sztul, E. S. (1999): Brefeldin A (BFA) disrupts the organization of the microtubule and the actin cytoskeletons. Eur. J. Cell Biol. 78, 1-14.
3. Alvarez, C., Fujita, H., Hubbard, A., Sztul, E. (1999): ER to Golgi transport: requirement for p115 at a pre-Golgi VTC stage. J. Cell Biol. 147, 1205-1222.
4. Alvarez, C., Garcia-Mata, R., Brandon, E., Sztul, E. (2003): COPI recruitment is modulated by a Rab1b - dependent mechanism. Mol. Biol. Cell 14, 2116-2127.
5. Alvarez, C., Garcia-Mata, R., Hauri, P., Sztul, E. (2001): The p115-interactive proteins GM130 and giantin participate in endoplasmic reticulum-Golgi traffic. J. Biol. Chem. 276, 2693-2700.
6. Bannykh, S. I., Balch, W. E. (1997): Membrane dynamics at the endoplasmic reticulum-Golgi interface. J. Cell Biol. 138, 1-4.
7. Barroso, M., Nelson, D. S., Sztul, E. (1995): Transcytosis-associated protein (TAP)/p115 is a general fusion factor required for binding of vesicles to acceptor membranes. Proc. Natl. Acad. Sci. USA 92, 527-531.
8. Bergmann, J. E. (1989): Using temperature-sensitive mutants of VSV to study membrane protein biogenesis. Methods Cell Biol. 32, 85-110.
9. Cao, X., Ballew, N., Barlowe, C. (1998): Initial docking of ER-derived vesicles requires Uso1p and Ypt1 but is independent of SNARE proteins. EMBO J. 17, 2156-2165.
10. Chardin P, McCormick F. (1999): Brefeldin A: the advantage of being uncompetitive. Cell 97, 153-155.
11. Dirac-Svejstrup, A. B., Shorter, J., Waters, M. G., Warren, G. (2000): Phosphorylation of the vesicle-tethering protein p115 by a casein kinase II-like enzyme is required for Golgi reassembly from isolated mitotic fragments. J. Cell Biol. 150, 475-488.
12. Garcia-Mata, R., Gao, Y., Alvarez, C., Sztul, E. (2000): The membrane transport factor p115 recycles only between homologous compartments in intact heterokaryons. Eur. J. Cell Biol. 79, 229-239.
13. Garcia-Mata, R., Sztul, E. (2003): The membrane-tethering protein p115 interacts with GBF1, an ARF guanine-nucleotide-exchange factor. EMBO Rep. 4, 320-325.
14. Hammond, A. T., Glick, B. S. (2000): Dynamics of transitional endoplasmic reticulum sites in vertebrate cells. Mol. Biol. Cell 11, 3013-3030.
15. Hong, W. (1998): Protein transport from the endoplasmic reticulum to the Golgi apparatus. J. Cell Sci. 111, 2831-2839.
16. Huang, W., Erikson, R. L. (1994): Constitutive activation of Mek1 by mutation of serine phosphorylation sites. Proc. Natl. Acad. Sci. USA 91, 8960-8963.
17. Itin, C., Schindler, R., Hauri, H. P. (1995): Targeting of protein ERGIC-53 to the ER/ERGIC/cis-Golgi recycling pathway. J. Cell Biol. 131, 57-67.
18. Jackson, C. L., Casanova, J. E. (2000): Turning on ARF: the Sec7 family of guanine-nucleotide-exchange factors. Trends Cell Biol. 10, 60-67.
19. Keller, P., Simons, K. (1997): Post-Golgi biosynthetic trafficking. J. Cell Sci. 110, 3001-3009.
20. Klumperman, J., Schweizer, A., Clausen, H., Tang, B. L., Hong, W., Oorschot, V., Hauri, H. P. (1998): The recycling pathway of protein ERGIC-53 and dynamics of the ER-Golgi intermediate compartment. J. Cell Sci. 111, 3411-3425.
21. Linstedt, A. D., Hauri, H. P. (1993): Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa. Mol. Biol. Cell 4, 679-693.
22. Linstedt, A., Jesch, S. A., Mehta, A., Lee, T. H., Garcia-Mata, R., Nelson, D. S., Sztul, E. (2000): Binding relationships of membrane tethering components. The giantin N-terminus and the GM130 N-terminus compete for binding to the p115 C-terminus. J. Biol. Chem. 275, 10196-10201.
23. Lippincott-Schwartz, J., Roberts, T., Hirschberg, K. (2000): Secretory protein trafficking and organelle dynamics in living cells. Annu. Rev. Cell Dev. Biol. 16, 557-589.
24. Nakajima, H., Hirata, A., Ogawa, Y., Yonehara, T., Yoda, K., Yamasaki, M. (1991): A cytoskeleton-related gene, USO1, is required for intracellular protein transport in Saccharomyces cerevisiae. J. Cell Biol. 113, 245-260.
25. Nakamura, N., Rabouille, C., Watson, R., Nilsson, T., Hui, N., Slusarewicz, P., Kreis, T. E., Warren, G. (1995): Characterization of a cis-Golgi matrix protein, GM130. J. Cell Biol. 131, 1715-1726.
26. Nakamura, N., Lowe, M., Levine, T. P., Rabouille, C., Warren, G. (1997): The vesicle docking protein p115 binds GM130, a cis-Golgi matrix protein, in a mitotically regulated manner. Cell 89, 445-455.
27. Nelson, D. S., Alvarez, C., Gao, Y. S., Garcia-Mata, R., Sztul, E. (1998): The membrane transport factor TAP/p115 cycles between the Golgi and earlier secretory compartments and contains distinct domains required for its localization and function. J. Cell Biol. 143, 319-331.
28. Palade, G. (1975): Intracellular aspects of the precess of protein synthesis. Science 189, 347-358.
29. Presley, J. F., Smith, C., Hirschberg, K., Miller, C., Cole, N. B., Zaal, K. J., Lippincott-Schwartz, J. (1998): Golgi membrane dynamics. Mol. Biol. Cell 9, 1617-1626.
30. Puthenveedu, M. A., Linstedt, A. (2001): Evidence that Golgi structure depends on a p115 activity that is independent of the vesicle tether components giantin and GM130. J. Cell Biol. 155, 227-238.
31. Rabouille, C., Misteli, T., Watson, R., Warren, G. (1995a): Reassembly of Golgi stacks from mitotic Golgi fragments in a cell-free system. J. Cell Biol. 129, 605-618.
32. Rabouille, C., Levine, T. P., Peters, J. M., Warren, G. (1995b): An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic Golgi fragments. Cell 82, 905-914.
33. Rabouille, C., Kondo, H., Newman, R., Hui, N., Freemont, P., Warren, G. (1998): Syntaxin 5 is a common component of the NSF- and p97-mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro. Cell 92, 603-610.
34. Schroer, T. A. (2000): Motors, clutches and brakes for membrane traffic: a commemorative review in honor of Thomas Kreis. Traffic 1, 3-10.
35. Schweizer, A., Peter, F., Van, P. N., Söling, H. D., Hauri, H. P. (1993): A luminal calcium-binding protein with a KDEL endoplasmic reticulum retention motif in the ER-Golgi intermediate compartment. Eur. J. Cell Biol. 60, 366-370.
36. Seemann, J., Jokitalo, E. J., Warren, G. (2000): The role of the tethering proteins p115 and GM130 in transport through the Golgi apparatus in vivo. Mol. Biol. Cell 11, 635-645.
37. Segev, N. (2001): Ypt and Rab GTPases: insight into functions through novel interactions. Curr. Opin. Cell Biol. 13, 500-511.
38. Shima, D. T., Haldar, K., Pepperkok, R., Watson, R., Warren, G. (1997): Partitioning of the Golgi apparatus during mitosis in living HeLa cells. J. Cell Biol. 137, 1211-1228.
39. Shorter, J., Warren, G. (1999): A role for the vesicle tethering protein, p115, in the post-mitotic stacking of reassembling Golgi cisternae in a cell-free system. J. Cell Biol. 146, 57-70.
40. Shorter, J., Beard, M., Seemann, J., Dirac-Svejstrup, B., Warren, G. (2002). Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115. J. Cell Biol. 157, 45-61.
41. Sohda, M., Misumi, Y., Yano, A., Takami, N., Ikehara, Y. (1998): Phosphorylation of the vesicle docking protein p115 regulates its association with the Golgi membrane. J. Biol. Chem. 273, 5385-5388.
42. Storrie, B., White, J., Rottger, S., Stelzer, E. H., Suganuma, T., Nilsson, T. (1998): Recycling of golgi-resident glycosyltransferases through the ER reveals a novel pathway and provides an explanation for nocodazole-induced Golgi scattering. J. Cell Biol. 143, 1505-1521.
43. Traub, L. M., Kornfeld, S. (1997): The trans-Golgi network: a late secretory sorting station. Curr. Opin. Cell Biol. 9, 527-533.
44. Tang, B. L., Low, S. H., Hong, W. (1995): Differential response of resident proteins and cycling proteins of the Golgi to brefeldin A. Eur. J. Cell Biol. 68, 199-205.
45. Taylor, R. S., Jones, S. M., Dahl, R. H., Nordeen, M. H., Howell, K. E. (1997): Characterization of the Golgi complex cleared of proteins in transit and examination of calcium uptake activities. Mol. Biol. Cell 8, 1911-1931.
46. Vale, R. D. (1992): Microtubule motors: many new models off the assembly line. Trends Biochem. Sci. 17, 300-304.
47. Vasudevan, C., Han, W., Tan, Y., Nie, Y., Li, D., Shome, K., Watkins, S. C., Levitan, E. S., Romero, G. (1998): The distribution and translocation of the G protein ADP-ribosylation factor 1 in live cells is determined by its GTPase activity. J. Cell Sci. 111, 1277-1285.
48. Ward, T. H., Polishchuk, R. S., Caplan, S., Hirschberg, K., Lippincott-Schwartz, J. (2001): Maintenance of Golgi structure and function depends on the integrity of ER export. J. Cell Biol. 155, 557-570.
49. Waters, M. G., Clary, D. O., Rothman, J. E. (1992): A novel 115-kDa peripheral membrane protein is required for intercisternal transport in the Golgi stack. J. Cell Biol. 118, 1015-1026.