Evidence that Golgi structure depends on a p115 activity that is independent of the vesicle tether components giantin and GM130

Journal of Cell Biology

Volumn 155, Issue 2, 2001, Pages 227-237

  Puthenveedu, Manojkumar A ^a   Linstedt, Adam D ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

COPI; Docking; Golgi structure; Mitosis; Tether

Indexed keywords

COATOMER PROTEIN; GIANTIN; PROTEIN; PROTEIN GM 130; PROTEIN P115; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; GOLGI COMPLEX; HUMAN; HUMAN CELL; MAMMAL; MITOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION;

ANTIBODIES; AUTOANTIGENS; CARRIER PROTEINS; COAT PROTEIN COMPLEX I; CYSTEINE ENDOPEPTIDASES; CYTOPLASMIC VESICLES; GOLGI APPARATUS; HELA CELLS; HUMANS; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MICROINJECTIONS; MITOSIS; MULTIENZYME COMPLEXES; PROTEASOME ENDOPEPTIDASE COMPLEX; VESICULAR TRANSPORT PROTEINS;

MAMMALIA;

EID: 0035889084     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200105005     Document Type: Article

References (43)

1. Signaling via mitogen-activated protein kinase kinase (MEK1) is required for Golgi fragmentation during mitosis
2. Rab1 recruitment of p115 into a cis-SNARE complex: Programming budding COPII vesicles for fusion
3. ER to Golgi transport: Requirement for p115 at a pre-Golgi VTC stage
4. The p115-interactive proteins, GM130 and giantin participate in ER-Golgi traffic
5. GRASP65, a protein involved in the stacking of Golgi cisternae
6. Mapping the interaction between GRASP65 and GM130, components of a protein complex involved in the stacking of Golgi cisternae
7. Transcytosis-associated protein (TAP)/p115 is a general fusion factor required for binding of vesicles to acceptor membranes
8. Procollagen traverses the Golgi stack without leaving the lumen of cisternae: Evidence for cisternal maturation
9. Phosphorylotion of the vesicle-tethering protein p115 by a casein kinase II-like enzyme is required for Golgi reassembly from isolated mitotic fragments
10. Inactivation and activation of various membranal enzymes of the cholesterol biosynthetic pathway by digitonin
11. A cisternal maturation mechanism can explain the asymmetry of the Golgi stack
12. Lectins and traffic in the secretory pathway
13. Inhibition of secretion by 1,3 cyclohexanebis(methylamine), a dibasic compound that interferes with coatomer function
14. The Golgi and endoplasmic reticulum remain independent during mitosis in HeLa cells
15. MEK and Cdc2 kinase are sequentially required for Golgi disassembly in MDCK cells by the mitotic Xenopus extracts
16. GTP hydrolysis by arf-1 mediates sorting and concentration of Golgi resident enzymes into functional COP I vesicles
17. Osmotically induced cell volume changes alter anterograde and retrograde transport, Golgi structure, and COPI dissociation
18. The amino-terminal domain of the Golgi protein giantin interacts directly with the vesicle-tethering p115
19. Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa
20. A C-terminally-anchored Golgi protein is inserted into the endoplasmic reticulum and then transported to the Golgi apparatus
21. Sequence and overexpression of GPP130/GIMPc: Evidence for saturable pH-sensitive targeting of a type II early Golgi membrane protein
22. Binding relationships of membrane tethering components. The giantin N terminus and the GM130 N terminus compete for binding to the p115 C terminus
23. Isolation of functional Golgi-derived vesicles with a possible role in retrograde transport
24. Cdc2 kinase phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosis
25. Mitotic Golgi fragments in HeLa cells and their role in the reassembly pathway
26. COP-coated vesicles are involved in the mirotic fragmentation of Golgi stacks in a cell-free system
27. Mitotic disassembly of the Golgi apparatus in vivo
28. A cyroskeleton-related gene, uso, is required for intracellular protein transport in Saccharomyces cerevisiae
29. The vesicle docking protein p115 binds GM130, a cis-Golgi matrix protein, in a mitotically regulated manner
30. The membrane transport factor TAP/p115 cycles between the Golgi and earlier secretory compartments and contains distinct domains required for its localization and function
31. Mechanisms of intracellular protein transport
32. The role of the tethering proteins p115 and GM130 in transport through the Golgi apparatus in vivo
33. Usol protein contains a coiled-coil rod region essential for protein transport from the ER to the Golgi apparatus in Saccharomyces cerevisiae
34. An ordered inheritance strategy for the Golgi apparatus: Visualization of mitotic dis-assembly reveals a role for the mitotic spindle
35. A role for the vesicle terhering protein, p115, in the post-mitotic stacking of reassembling Golgi cisternae in a cell-free system
36. GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system
37. Phosphorylation of the vesicle docking protein p115 regulates its association with the Golgi membrane
38. A role for giantin in docking COPI vesicles to Golgi membranes
39. Recycling of Golgi-resident glycosyltransferases through the ER reveals a novel pathway and provides an explanation for nocodazole-induced Golgi scattering
40. Membrane traffic and organelle division
41. Mitotic disassembly of the mammalian Golgi apparatus
42. A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack
43. Golgi membranes are absorbed into and reemerge from the ER during mitosis