메뉴 건너뛰기




Volumn 48, Issue 9, 2003, Pages 2396-2401

Interferon-α: A new target for therapy in systemic lupus erythematosus?

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; AUTOANTIBODY; BETA INTERFERON; CYTOKINE; GAMMA INTERFERON; INTERFERON;

EID: 0141676493     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.11226     Document Type: Editorial
Times cited : (86)

References (42)
  • 1
    • 0141633010 scopus 로고    scopus 로고
    • Expression of the markers BDCA-2 and BDCA-4 and production of interferon-α by plasmacytoid dendritic cells in systemic lupus erythematosus
    • Blomberg S, Eloranta M-L, Magnusson M, Alm GV, Rönnblom L. Expression of the markers BDCA-2 and BDCA-4 and production of interferon-α by plasmacytoid dendritic cells in systemic lupus erythematosus. Arthritis Rheum 2003;48:2524-32.
    • (2003) Arthritis Rheum , vol.48 , pp. 2524-2532
    • Blomberg, S.1    Eloranta, M.-L.2    Magnusson, M.3    Alm, G.V.4    Rönnblom, L.5
  • 2
    • 77957168195 scopus 로고
    • Interferon
    • Issacs A. Interferon. Adv Virus Res 1963;10:1-38.
    • (1963) Adv Virus Res , vol.10 , pp. 1-38
    • Issacs, A.1
  • 4
    • 0345076982 scopus 로고    scopus 로고
    • IFN-tau: A novel subtype I IFN1. Structural characteristics, non-ubiquitous expression, structure-function relationships, a pregnancy hormonal embryonic signal and cross-species therapeutic potentialities
    • Martal JL, Chene NM, Huynh LP, L'Haridon RM, Reinaud PB, Guillomot MW, et al. IFN-tau: A novel subtype I IFN1. Structural characteristics, non-ubiquitous expression, structure-function relationships, a pregnancy hormonal embryonic signal and cross-species therapeutic potentialities. Biochimie 1998;80:755-77.
    • (1998) Biochimie , vol.80 , pp. 755-777
    • Martal, J.L.1    Chene, N.M.2    Huynh, L.P.3    L'Haridon, R.M.4    Reinaud, P.B.5    Guillomot, M.W.6
  • 5
    • 0019972228 scopus 로고
    • Systemic lupus erythematosus: Presence in human serum of an unusual acid-labile leukocyte interferon
    • Preble OT, Black RJ, Friedman RM, Klippel JH, Vilcek J. Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon. Science 1982;216:429-31.
    • (1982) Science , vol.216 , pp. 429-431
    • Preble, O.T.1    Black, R.J.2    Friedman, R.M.3    Klippel, J.H.4    Vilcek, J.5
  • 6
    • 0025357153 scopus 로고
    • Serum activity that confers acid lability to α-interferon in systemic lupus erythematosus: Its association with disease activity and its independence from circulating α-interferon
    • Yee AMF, Yip YK, Fischer HD, Buyon JP. Serum activity that confers acid lability to α-interferon in systemic lupus erythematosus: its association with disease activity and its independence from circulating α-interferon. Arthritis Rheum 1990;33:563-8.
    • (1990) Arthritis Rheum , vol.33 , pp. 563-568
    • Yee, A.M.F.1    Yip, Y.K.2    Fischer, H.D.3    Buyon, J.P.4
  • 7
    • 0019861388 scopus 로고
    • Human lupus inclusions and interferon
    • Rich SA. Human lupus inclusions and interferon. Science 1981;213:772-5.
    • (1981) Science , vol.213 , pp. 772-775
    • Rich, S.A.1
  • 8
    • 0025057503 scopus 로고
    • Possible induction of systemic lupus erythematosus by interferon-α treatment in a patient with a malignant carcinoid tumour
    • Rönnblom LE, Alm GV, Öberg KE. Possible induction of systemic lupus erythematosus by interferon-α treatment in a patient with a malignant carcinoid tumour. J Intern Med 1990;227:207-10.
    • (1990) J Intern Med , vol.227 , pp. 207-210
    • Rönnblom, L.E.1    Alm, G.V.2    Öberg, K.E.3
  • 9
    • 0030018280 scopus 로고    scopus 로고
    • The cell surface phenotype of human natural interferon-α producing cells as determined by flow cytometry
    • Svensson H, Johannisson A, Nikkila T, Alm GV, Cederblad B. The cell surface phenotype of human natural interferon-α producing cells as determined by flow cytometry. Scand J Immunol 1996;44:164-72.
    • (1996) Scand J Immunol , vol.44 , pp. 164-172
    • Svensson, H.1    Johannisson, A.2    Nikkila, T.3    Alm, G.V.4    Cederblad, B.5
  • 10
    • 0032950459 scopus 로고    scopus 로고
    • Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-α) production acting on leucocytes resembling immature dendritic cells
    • Vallin H, Blomberg S, Alm GV, Cederblad B, Rönnblom L. Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-α) production acting on leucocytes resembling immature dendritic cells. Clin Exp Immunol 1999;115:196-202.
    • (1999) Clin Exp Immunol , vol.115 , pp. 196-202
    • Vallin, H.1    Blomberg, S.2    Alm, G.V.3    Cederblad, B.4    Rönnblom, L.5
  • 11
    • 0033485756 scopus 로고    scopus 로고
    • Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-α inducer in systemic lupus erythematosus
    • Vallin H, Perers A, Alm GV, Rönnblom L. Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-α inducer in systemic lupus erythematosus. J Immunol 1999;163:6306-13.
    • (1999) J Immunol , vol.163 , pp. 6306-6313
    • Vallin, H.1    Perers, A.2    Alm, G.V.3    Rönnblom, L.4
  • 12
    • 0034665534 scopus 로고    scopus 로고
    • The combination of apoptotic U937 cells and lupus IgG is a potent IFN-α inducer
    • Båve U, Alm GV, Rönnblom L. The combination of apoptotic U937 cells and lupus IgG is a potent IFN-α inducer. J Immunol 2000;165:3519-26.
    • (2000) J Immunol , vol.165 , pp. 3519-3526
    • Båve, U.1    Alm, G.V.2    Rönnblom, L.3
  • 13
    • 0035421308 scopus 로고    scopus 로고
    • Activation of natural interferon-α producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines
    • Båve U, Vallin H, Alm GV, Rönnblom L. Activation of natural interferon-α producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines. J Autoimmun 2001;17:71-80.
    • (2001) J Autoimmun , vol.17 , pp. 71-80
    • Båve, U.1    Vallin, H.2    Alm, G.V.3    Rönnblom, L.4
  • 14
    • 0035708710 scopus 로고    scopus 로고
    • Importance of CpG dinucleotides in activation of natural IFN-alpha-producing cells by a lupus-related oligodeoxynucleotide
    • Magnusson M, Magnusson S, Vallin H, Rönnblom L, Alm GV. Importance of CpG dinucleotides in activation of natural IFN-alpha-producing cells by a lupus-related oligodeoxynucleotide. Scand J Immunol 2001;54:543-50.
    • (2001) Scand J Immunol , vol.54 , pp. 543-550
    • Magnusson, M.1    Magnusson, S.2    Vallin, H.3    Rönnblom, L.4    Alm, G.V.5
  • 15
    • 0032586001 scopus 로고    scopus 로고
    • FcgammaRII (CD32)-dependent induction of interferon-α by serum from patients with lupus erythematosus
    • Batteux F, Palmer P, Daeron M, Weill B, Lebon P. FcgammaRII (CD32)-dependent induction of interferon-α by serum from patients with lupus erythematosus. Eur Cytokine Netw 1999;10:509-14.
    • (1999) Eur Cytokine Netw , vol.10 , pp. 509-514
    • Batteux, F.1    Palmer, P.2    Daeron, M.3    Weill, B.4    Lebon, P.5
  • 17
    • 0035905409 scopus 로고    scopus 로고
    • A pivotal role for the natural interferon α-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus
    • Rönnblom L, Alm GV. A pivotal role for the natural interferon α-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus. J Exp Med 2001;194:F59-63.
    • (2001) J Exp Med , vol.194
    • Rönnblom, L.1    Alm, G.V.2
  • 18
    • 0034533825 scopus 로고    scopus 로고
    • Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies
    • Bengtsson AA, Sturfelt G, Truedsson L, Blomberg J, Alm G, Vallin H, et al. Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies. Lupus 2000;9:664-71.
    • (2000) Lupus , vol.9 , pp. 664-671
    • Bengtsson, A.A.1    Sturfelt, G.2    Truedsson, L.3    Blomberg, J.4    Alm, G.5    Vallin, H.6
  • 19
    • 0025326912 scopus 로고
    • Immunogenic DNA-related factors: Nucleosomes spontaneously released from normal murine lymphoid cells stimulate proliferation and immunoglobulin synthesis of normal mouse lymphocytes
    • Bell DA, Morrison B, VandenBygaart P. Immunogenic DNA-related factors: nucleosomes spontaneously released from normal murine lymphoid cells stimulate proliferation and immunoglobulin synthesis of normal mouse lymphocytes. J Clin Invest 1990;85:1487-96.
    • (1990) J Clin Invest , vol.85 , pp. 1487-1496
    • Bell, D.A.1    Morrison, B.2    VandenBygaart, P.3
  • 21
    • 0035051130 scopus 로고    scopus 로고
    • Alterations of dendritic cells in systemic lupus erythematosus: Phenotypic and functional deficiencies
    • Scheinecker C, Zwölfer B, Köller M, Männer G, Smolen JS. Alterations of dendritic cells in systemic lupus erythematosus: phenotypic and functional deficiencies. Arthritis Rheum 2001;44:856-65.
    • (2001) Arthritis Rheum , vol.44 , pp. 856-865
    • Scheinecker, C.1    Zwölfer, B.2    Köller, M.3    Männer, G.4    Smolen, J.S.5
  • 22
    • 0034913451 scopus 로고    scopus 로고
    • Presence of cutaneous interferon-α producing cells in patients with systemic lupus erythematosus
    • Blomberg S, Eloranta M-L, Cederblad B, Nordlin K, Alm GV, Rönnblom L. Presence of cutaneous interferon-α producing cells in patients with systemic lupus erythematosus. Lupus 2001;10:484-90.
    • (2001) Lupus , vol.10 , pp. 484-490
    • Blomberg, S.1    Eloranta, M.-L.2    Cederblad, B.3    Nordlin, K.4    Alm, G.V.5    Rönnblom, L.6
  • 23
    • 0035403969 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells (natural interferon-α/ β-producing cells) accumulate in cutaneous lupus erythematosus lesions
    • Farkas L, Beiske K, Lund-Johansen F, Brandtzaeg P, Jahnsen FL. Plasmacytoid dendritic cells (natural interferon-α/β-producing cells) accumulate in cutaneous lupus erythematosus lesions. Am J Pathol 2001;159:237-43.
    • (2001) Am J Pathol , vol.159 , pp. 237-243
    • Farkas, L.1    Beiske, K.2    Lund-Johansen, F.3    Brandtzaeg, P.4    Jahnsen, F.L.5
  • 24
    • 0035905321 scopus 로고    scopus 로고
    • BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferonα/β induction
    • Dzionek A, Sohma Y, Nagafune J, Cella M, Colonna M, Facchetti F, et al. BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferonα/β induction. J Exp Med 2001;194:1823-34.
    • (2001) J Exp Med , vol.194 , pp. 1823-1834
    • Dzionek, A.1    Sohma, Y.2    Nagafune, J.3    Cella, M.4    Colonna, M.5    Facchetti, F.6
  • 25
    • 0035900481 scopus 로고    scopus 로고
    • Induction of dendritic cell differentiation by IFN-α in systemic lupus erythematosus
    • Blanco P, Palucka AK, Gill M, Pascual V, Banchereau J. Induction of dendritic cell differentiation by IFN-α in systemic lupus erythematosus. Science 2001;294:1540-3.
    • (2001) Science , vol.294 , pp. 1540-1543
    • Blanco, P.1    Palucka, A.K.2    Gill, M.3    Pascual, V.4    Banchereau, J.5
  • 27
  • 29
    • 0020526160 scopus 로고
    • Interferon-induced 2′-5′ adenylate synthetase in vivo and interferon production in vitro by lymphocytes from systemic lupus erythematosus patients with and without circulating interferon
    • Preble OT, Rothko K, Klippel JH, Friedman RM, Johnston MI. Interferon-induced 2′-5′ adenylate synthetase in vivo and interferon production in vitro by lymphocytes from systemic lupus erythematosus patients with and without circulating interferon. J Exp Med 1983;157:2140-6.
    • (1983) J Exp Med , vol.157 , pp. 2140-2146
    • Preble, O.T.1    Rothko, K.2    Klippel, J.H.3    Friedman, R.M.4    Johnston, M.I.5
  • 30
    • 0034814052 scopus 로고    scopus 로고
    • Evidence for an interferon-inducible gene, Ifi2O2, in the susceptibility to systemic lupus
    • Rozzo SJ, Allard JD, Choubey D, Vyse TJ, Izui S, Peltz G, et al. Evidence for an interferon-inducible gene, Ifi2O2, in the susceptibility to systemic lupus. Immunity 2001;15:435-43.
    • (2001) Immunity , vol.15 , pp. 435-443
    • Rozzo, S.J.1    Allard, J.D.2    Choubey, D.3    Vyse, T.J.4    Izui, S.5    Peltz, G.6
  • 32
    • 0042971553 scopus 로고    scopus 로고
    • Studies of autologous T cell activation in the Kunkel laboratory
    • Crow MK. Studies of autologous T cell activation in the Kunkel laboratory. Lupus 2003;12:163-9.
    • (2003) Lupus , vol.12 , pp. 163-169
    • Crow, M.K.1
  • 33
    • 0036681814 scopus 로고    scopus 로고
    • T cell proliferation induced by autologous non-T cells is a response to apoptotic cells processed by dendritic cells
    • Chernysheva AD, Kirou KA, Crow MK. T cell proliferation induced by autologous non-T cells is a response to apoptotic cells processed by dendritic cells. J Immunol 2002;169:1241-50.
    • (2002) J Immunol , vol.169 , pp. 1241-1250
    • Chernysheva, A.D.1    Kirou, K.A.2    Crow, M.K.3
  • 34
    • 0034906508 scopus 로고    scopus 로고
    • The role of CpG sequences in the induction of anti-DNA antibodies
    • Pisetsky DS, Wenk KS, Reich CF III. The role of CpG sequences in the induction of anti-DNA antibodies. Clin Immunol 2001;100:157-63.
    • (2001) Clin Immunol , vol.100 , pp. 157-163
    • Pisetsky, D.S.1    Wenk, K.S.2    Reich C.F. III3
  • 35
    • 0032529213 scopus 로고    scopus 로고
    • Type I IFNs enhance the terminal differentiation of dendritic cells
    • Luft T, Pang KC, Thomas E, Hertzog P, Hart DN, Trapani J, et al. Type I IFNs enhance the terminal differentiation of dendritic cells. J Immunol 1998;161:1947-53.
    • (1998) J Immunol , vol.161 , pp. 1947-1953
    • Luft, T.1    Pang, K.C.2    Thomas, E.3    Hertzog, P.4    Hart, D.N.5    Trapani, J.6
  • 36
    • 0031656896 scopus 로고    scopus 로고
    • Interferon-α and granulocyte-macrophage colony-stimulating factor differentiate peripheral blood monocytes into potent antigen-presenting cells
    • Paquette RL, Hsu NC, Kiertscher SM, Park AN, Tran L, Roth MD, et al. Interferon-α and granulocyte-macrophage colony-stimulating factor differentiate peripheral blood monocytes into potent antigen-presenting cells. J Leukoc Biol 1998;64:358-67.
    • (1998) J Leukoc Biol , vol.64 , pp. 358-367
    • Paquette, R.L.1    Hsu, N.C.2    Kiertscher, S.M.3    Park, A.N.4    Tran, L.5    Roth, M.D.6
  • 37
    • 9344260280 scopus 로고    scopus 로고
    • Interferon-alpha stimulates production of interleukin-10 in activated CD4+ T cells and monocytes
    • Aman MJ, Tretter T, Eisenbeis I, Bug G, Decker T, Aulitzky WE, et al. Interferon-alpha stimulates production of interleukin-10 in activated CD4+ T cells and monocytes. Blood 1996;87:4731-6.
    • (1996) Blood , vol.87 , pp. 4731-4736
    • Aman, M.J.1    Tretter, T.2    Eisenbeis, I.3    Bug, G.4    Decker, T.5    Aulitzky, W.E.6
  • 38
    • 0035030376 scopus 로고    scopus 로고
    • Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo
    • Le Bon A, Schiavoni G, D'Agostino G, Gresser I, Belardelli G, Tough D. Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity 2001;14:461-70.
    • (2001) Immunity , vol.14 , pp. 461-470
    • Le Bon, A.1    Schiavoni, G.2    D'Agostino, G.3    Gresser, I.4    Belardelli, G.5    Tough, D.6
  • 40
    • 0028330345 scopus 로고
    • Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus
    • Emlen W, Niebur J, Kadera R. Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J Immunol 1994;152:3685-92.
    • (1994) J Immunol , vol.152 , pp. 3685-3692
    • Emlen, W.1    Niebur, J.2    Kadera, R.3
  • 41
    • 0030778080 scopus 로고    scopus 로고
    • Interleukin-10 promotes activation-induced cell death of SLE lymphocytes mediated by Fas ligand
    • Georgescu L, Vakkalanka RK, Elkon KB, Crow MK. Interleukin-10 promotes activation-induced cell death of SLE lymphocytes mediated by Fas ligand. J Clin Invest 1997;100:2622-33.
    • (1997) J Clin Invest , vol.100 , pp. 2622-2633
    • Georgescu, L.1    Vakkalanka, R.K.2    Elkon, K.B.3    Crow, M.K.4
  • 42
    • 0035823645 scopus 로고    scopus 로고
    • Characterization and humanization of a monoclonal antibody that neutralizes human leukocyte interferon: A candidate therapeutic for IDDM and SLE
    • Chuntharapai A, Lai J, Huang X, Gibbs V, Kim KJ, Presta LG, et al. Characterization and humanization of a monoclonal antibody that neutralizes human leukocyte interferon: a candidate therapeutic for IDDM and SLE. Cytokine 2001;15:250-60.
    • (2001) Cytokine , vol.15 , pp. 250-260
    • Chuntharapai, A.1    Lai, J.2    Huang, X.3    Gibbs, V.4    Kim, K.J.5    Presta, L.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.