Independent signals determine the subcellular localization of NEP in prostate cancer cells

Biochemical and Biophysical Research Communications

Volumn 310, Issue 3, 2003, Pages 919-926

  Gomes, Iara ^a   Aumüller, Gerhard ^a   Wennemuth, Gunther ^a   Bette, Michael ^a   Albrecht, Martin ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Green fluorescence protein; Neutral endopeptidase 24.11; Prostate; Sequence analysis

Indexed keywords

AMINO TERMINAL SEQUENCE; ARTICLE; CANCER CELL; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE INSERTION; GENE LOCATION; GENE SEQUENCE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROSTATE CANCER; SIGNAL TRANSDUCTION;

VECTORS;

EID: 0141645311     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.09.096     Document Type: Article

References (51)

1. Monod L., Hamou M.F., Ronco P., Verroust P., de Tribolet N. Expression of cALLa/NEP on gliomas: a possible marker of malignancy. Acta Neurochir. 114:1992;3-7.
2. Papandreou C.N., Usmani B., Geng Y., Bogenrieder T., Freeman R., Wilk S., Finstad C.L., Reuter V.E., Powell C.T., Scheinberg D., Magill C., Scher H.I., Albino A.P., Nanus D.M. Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression. Nat. Med. 4:1998;50-57.
3. Renneberg H., Albrecht M., Kurek R., Krause E., Lottspeich F., Aumuller G., Wilhelm B. Identification and characterization of neutral endopeptidase (EC 3.4. 24. 11) from human prostasomes - localization in prostatic tissue and cell lines. Prostate. 46:2001;173-183.
4. Gohring B., Holzhausen H.J., Meye A., Heynemann H., Rebmann U., Langner J., Riemann D. Endopeptidase 24.11/CD10 is down-regulated in renal cell cancer. Int. J. Mol. Med. 2:1998;409-414.
5. Sato Y., Itoh F., Hinoda Y., Ohe Y., Nakagawa N., Ueda R., Yachi A., Imai K. Expression of CD10/neutral endopeptidase in normal and malignant tissues of the human stomach and colon. J. Gastroenterol. 31:1996;12-17.
6. Suzuki T., Kikkawa F., Ino K., Nagasaka T., Tamakoshi K., Mizutani S. Imbalance between neutral endopeptidase 24.11 and endothelin-1 expression in human endometrial carcinoma. Oncology. 60:2001;258-267.
7. Takaki Y., Iwata N., Tsubuki S., Taniguchi S., Toyoshima S., Lu B., Gerard N.P., Gerard C., Lee H.J., Shirotani K., Saido T.C. Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain. J. Biochem. (Tokyo). 128:2000;897-902.
8. Baraniuk J.N., Ohkubo K., Kwon O.J., Mak J., Ali M., Davies R., Twort C., Kaliner M., Letarte M., Barnes P.J. Localization of neutral endopeptidase (NEP) mRNA in human bronchi. Eur. Respir. J. 8:1995;1458-1464.
9. Cohen A.J., Bunn P.A., Franklin W., Magill-Solc C., Hartmann C., Helfrich B., Gilman L., Folkvord J., Helm K., Miller Y.E. Neutral endopeptidase: variable expression in human lung, inactivation in lung cancer, and modulation of peptide-induced calcium flux. Cancer Res. 56:1996;831-839.
10. Koiso K., Akaza H., Ohtani M., Miyanaga N., Aoyagi K. A new tumor marker for bladder cancer. Int. J. Urol. 1:1994;33-36.
11. Shen R., Sumitomo M., Dai J., Hardy D.O., Navarro D., Usmani B., Papandreou C.N., Hersh L.B., Shipp M.A., Freedman L.P., Nanus D.M. Identification and characterization of two androgen response regions in the human neutral endopeptidase gene. Mol. Cell. Endocrinol. 170:2000;131-142.
12. Turner A.J., Isaac R.E., Coates D. The neprilysin (NEP) family of zinc metalloendopeptidases: genomics and function. Bioessays. 23:2001;261-269.
13. Ishimaru F., Mari B., Shipp M.A. The type 2 CD10/neutral endopeptidase 24.11 promoter: functional characterization and tissue-specific regulation by CBF/NF-Y isoforms. Blood. 89:1997;4136-4145.
14. Nagle R.B., Ahmann F.R., McDaniel K.M., Paquin M.L., Clark V.A., Celniker A. Cytokeratin characterization of human prostatic carcinoma and its derived cell lines. Cancer Res. 47:1987;281-286.
15. Sumitomo M., Shen R., Goldberg J.S., Dai J., Navarro D., Nanus D.M. Neutral endopeptidase promotes phorbol ester-induced apoptosis in prostate cancer cells by inhibiting neuropeptide-induced protein kinase C delta degradation. Cancer Res. 60:2000;6590-6596.
16. Albrecht M., Gillen S., Wilhelm B., Doroszewicz J., Aumuller G. Expression, localization and activity of neutral endopeptidase in cultured cells of benign prostatic hyperplasia and prostate cancer. J. Urol. 168:2002;336-342.
17. Horoszewicz J.S., Leong S.S., Chu T.M., Wajsman Z.L., Friedman M., Papsidero L., Kim U., Chai L.S., Kakati S., Arya S.K., Sandberg A.A. The LNCaP cell line - a new model for studies on human prostatic carcinoma. Prog. Clin. Biol. Res. 37:1980;115-132.
18. Janssen M., Albrecht M., Moschler O., Renneberg H., Fritz B., Aumuller G., Konrad L. Cell lineage characteristics of human prostatic stromal cells cultured in vitro. Prostate. 43:2000;20-30.
19. Albrecht M., Janssen M., Konrad L., Renneberg H., Aumuller G. Effects of dexamethasone on proliferation of and fibronectin synthesis by human primary prostatic stromal cells in vitro. Andrologia. 34:2002;11-21.
20. Altschul S.F., Madden T.L., Schaffer A.A., Zhang J., Zhang Z., Miller W., Lipman D.J. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25:1997;3389-3402.
21. Kelley L.A., MacCallum R.M., Sternberg M.J. Enhanced genome annotation using structural profiles in the program 3D- PSSM. J. Mol. Biol. 299:2000;499-520.
22. Hofmann K., Bucher P., Falquet L., Bairoch A. The PROSITE database, its status in 1999. Nucleic Acids Res. 27:1999;215-219.
23. Gupta R., Jung E., Gooley A.A., Williams K.L., Brunak S., Hansen J. Scanning the available Dictyostelium discoideum proteome for O-linked GlcNAc glycosylation sites using neural networks. Glycobiology. 9:1999;1009-1022.
24. Nielsen H., Engelbrecht J., Brunak S., von Heijne G. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10:1997;1-6.
25. Blom N., Gammeltoft S., Brunak S. Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. J. Mol. Biol. 294:1999;1351-1362.
26. Hooper N.M. Families of zinc metalloproteases. FEBS Lett. 354:1994;1-6.
27. Roques B.P. Cell surface metallopeptidases involved in blood pressure regulation: structure, inhibition and clinical perspectives. Pathol. Biol. (Paris). 46:1998;191-200.
28. Tiraboschi G., Jullian N., Thery V., Antonczak S., Fournie-Zaluski M.C., Roques B.P. A three-dimensional construction of the active site (region 507-749) of human neutral endopeptidase (EC.3.4.24.11). Protein Eng. 12:1999;141-149.
29. Devault A., Sales V., Nault C., Beaumont A., Roques B., Crine P., Boileau G. Exploration of the catalytic site of endopeptidase 24.11 by site-directed mutagenesis. Histidine residues 583 and 587 are essential for catalysis. FEBS Lett. 231:1988;54-58.
30. Bur D., Dale G.E., Oefner C. A three-dimensional model of endothelin-converting enzyme (ECE) based on the X-ray structure of neutral endopeptidase 24.11 (NEP). Protein Eng. 14:2001;337-341.
31. Dion N., Le Moual H., Crine P., Boileau G. Kinetic evidence that His-711 of neutral endopeptidase 24.11 is involved in stabilization of the transition state. FEBS Lett. 318:1993;301-304.
32. Le Moual H., Dion N., Roques B.P., Crine P., Boileau G. Asp650 is crucial for catalytic activity of neutral endopeptidase 24-11. Eur. J. Biochem. 221:1994;475-480.
33. Beaumont A., Le Moual H., Boileau G., Crine P., Roques B.P. Evidence that both arginine 102 and arginine 747 are involved in substrate binding to neutral endopeptidase (EC 3.4.24.11). J. Biol. Chem. 266:1991;214-220.
34. Dion N., Le Moual H., Fournie-Zaluski M.C., Roques B.P., Crine P., Boileau G. Evidence that Asn542 of neprilysin (EC 3.4.24.11) is involved in binding of the P. 2′ residue of substrates and inhibitors Biochem. J. 311:1995;623-627.
35. Navarrete Santos A., Wulfanger J., Helbing G., Blosz T., Langner J., Riemann D. Two C-terminal cysteines are necessary for proper folding of the peptidase neprilysin/CD10. Biochem. Biophys. Res. Commun. 295:2002;423-427.
36. Ghaddar G., Ruchon A.F., Carpentier M., Marcinkiewicz M., Seidah N.G., Crine P., Desgroseillers L., Boileau G. Molecular cloning and biochemical characterization of a new mouse testis soluble-zinc-metallopeptidase of the neprilysin family. Biochem. J. 347:2000;419-429.
37. Turner A.J., Tanzawa K. Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX. FASEB J. 11:1997;355-364.
38. Sumitomo M., Shen R., Walburg M., Dai J., Geng Y., Navarro D., Boileau G., Papandreou C.N., Giancotti F.G., Knudsen B., Nanus D.M. Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling. J. Clin. Invest. 106:2000;1399-1407.
39. Vida T.A., Hersh L.B. Glycosylation variants of endopeptidase-24.11 ('enkephalinase'). Neuropeptides. 21:1992;245-255.
40. Chen C.Y., Salles G., Seldin M.F., Kister A.E., Reinherz E.L., Shipp M.A. Murine common acute lymphoblastic leukemia antigen (CD10 neutral endopeptidase 24.11). Molecular characterization, chromosomal localization, and modeling of the active site. J. Immunol. 148:1992;2817-2825.
41. Lafrance M.H., Vezina C., Wang Q., Boileau G., Crine P., Lemay G. Role of glycosylation in transport and enzymic activity of neutral endopeptidase-24.11. Biochem. J. 302:1994;451-454.
42. Shipp M.A., Richardson N.E., Sayre P.H., Brown N.R., Masteller E.L., Clayton L.K., Ritz J., Reinherz E.L. Molecular cloning of the common acute lymphoblastic leukemia antigen (CALLA) identifies a type II integral membrane protein. Proc. Natl. Acad. Sci. USA. 85:1988;4819-4823.
43. Barker P.E., Shipp M.A., D'Adamio L., Masteller E.L., Reinherz E.L. The common acute lymphoblastic leukemia antigen gene maps to chromosomal region 3 (q21-q27). J. Immunol. 142:1989;283-287.
44. Haouas H., Morello D., Lavenu A., Billard M., Jasmin C., Boucheix C. Characterization of the. 5′ region of the CD10/neutral endopeptidase 24. 11 gene Biochem. Biophys. Res. Commun. 207:1995;933-942.
45. Ohshima K., Kawasaki C., Muta H., Muta K., Deyev V., Haraoka S., Suzumiya J., Podack E.R., Kikuchi M. CD10 and Bcl10 expression in diffuse large B-cell lymphoma: CD10 is a marker of improved prognosis. Histopathology. 39:2001;156-162.
46. Barnes K., Turner A.J., Kenny A.J. Membrane localization of endopeptidase-24.11 and peptidyl dipeptidase A (angiotensin converting enzyme) in the pig brain: a study using subcellular fractionation and electron microscopic immunocytochemistry. J. Neurochem. 58:1992;2088-2096.
47. Toyoda M., Nakamura M., Makino T., Kagoura M., Morohashi M. Sebaceous glands in acne patients express high levels of neutral endopeptidase. Exp. Dermatol. 11:2002;241-247.
48. Jans D.A., Xiao C.Y., Lam M.H. Nuclear targeting signal recognition: a key control point in nuclear transport? Bioessays. 22:2000;532-544.
49. Corneo B., Benmerah A., Villartay J.P. A short peptide at the C terminus is responsible for the nuclear localization of RAG2. Eur. J. Immunol. 32:2002;2068-2073.
50. Sonnichsen B., Fullekrug J., Nguyen Van P., Diekmann W., Robinson D.G., Mieskes G. Retention and retrieval: both mechanisms cooperate to maintain calreticulin in the endoplasmic reticulum. J. Cell Sci. 107:1994;2705-2717.
51. Xia H., Hornby Z.D., Malenka R.C. An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits. Neuropharmacology. 41:2001;714-723.