Cloning and characterization of the promoter region of the mouse frizzled-related protein 4 gene

Biological Chemistry

Volumn 384, Issue 8, 2003, Pages 1147-1154

  Wai Wong, Vincent Kam ^a   Ping Yam, Judy Wai ^a   Hsiao, W L Wendy ^a,b  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

cAMP responsive element binding protein; Frizzled related protein; Neuron restrictive silencer element

Indexed keywords

ALKALINE PHOSPHATASE; CCAAT ENHANCER BINDING PROTEIN BETA; CIS ACTING ELEMENT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FRIZZLED RELATED PROTEIN 4; STAT3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG; WNT PROTEIN;

ARTICLE; BINDING SITE; BIOASSAY; CLUSTER ANALYSIS; CONTROLLED STUDY; DATA ANALYSIS; ENZYME ACTIVITY; GENE ACTIVITY; GENE CLUSTER; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC REGULATION; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REPORTER GENE; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

RODENTIA;

EID: 0141626773     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2003.127     Document Type: Article

References (43)

1. Bafico, A., Gazit, A., Pramila, T., Finch, P. W., Yaniv, A., and Aaronson, S. A. (1999). Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP Inhibition of Wnt signaling. J. Biol. Chem. 274, 16180-16187.
2. Barker, N., and Clevers, H. (2000). Catenins, Wnt signaling and cancer. Bioessays 22, 961-965.
3. Bergwitz, C., Wendlandt, T., Kispert, A., and Brabant, G. (2001). Wnts differentially regulate colony growth and differentiation of chondrogenic rat calvaria cells. Biochim. Biophys. Acta 1538, 129-140.
4. Bhanot, P., Brink, M., Samos, C.H., Hsieh, J.C., Wang, Y., Macke, J. P., Andrew, D., Nathans, J., and Nusse, R. (1996). A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382, 225-230.
5. Chang, J.T., Esumi, N., Moore, K., Li, Y., Zhang, S., Chew, C., Goodman, B., Rattner, A., Moody, S., Stetten, G., Campochiaro, P.A., and Zack, D.J. (1999). Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium. Hum. Mol. Genet. 8, 575-583.
6. Dann, C.E., Hsieh, J.C., Rattner, A., Sharma, D., Nathans, J., and Leahy, D.J. (2001). Insights into Wnt binding and signaling from the structures of two Frizzled cysteine-rich domains. Nature 412, 86-90.
7. Dennis, S., Aikawa, M., Szeto, W., d'Amore, P.A. and Papkoff, J. (1999). A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates wnt-1 signaling. J. Cell Sci. 112, 3815-3820.
8. Dignam, J.D., Lebovitz, R.M., and Roeder, R.G. (1983). Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11, 1475-1489.
9. Ellies, D.L., Church, V., Francis-West, P., and Lumsden, A. (2000). The WNT antagonist cSFRP2 modulates programmed cell death in the developing hindbrain. Development (Suppl.) 127, 5285-5295.
10. Finch, P.W., He, X., Kelly, M.J., Uren, A., Schaudies, R.P., Popescu, N.C., Rudikoff, S., Aaronson, S.A., Varmus, H.E., and Rubin, J.S. (1997). Purification and molecular cloning of a secreted, frizzled-related antagonist of Wnt action. Proc. Natl. Acad. Sci. USA 94, 6770-6775.
11. Fujita, M., Ogawa S., Fukuoka H., Tsukui T., Nemoto N., Tsutsumi O., Ouchi Y., and Inoue, S. (2002). Differential expression of secreted frizzled-related protein 4 in decidual cells during pregnancy. J. Mol. Endo. 28, 213-223.
12. Fukuhara, K., Kariya, M., Kita, M., Shime, H., Kanamori, T., Kosaka, C., Orii, A. Fujita, J., and Fujii, S. (2002). Secreted frizzled related protein 1 is overexpressed in uterine leiomyomas, associated with a high estrogenic environment and unrelated to proliferative activity. J. Clin. Endo. Metab. 87, 1729-1736.
13. He, X., Saint-Jeannet, J.P., Wang, Y., Nathans, J., Dawid, I.B., and Varmus, H. E. (1997). A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science 275, 1652-1654.
14. Hoang, B., Moos, M., Vukicevic, S., and Luyten, F.P. (1996). Primary structure and tissue distribution of Frzb, a novel protein related to Drosophila frizzled, suggest a role in skeletal morphogenesis. J. Biol. Chem. 271, 26131-26137.
15. Houart, C., Caneparo, L., Heisenberg, C., Barth, K., Take-Uchi, M., and Wilson, S. (2002). Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling. Neuron 35, 255-265.
16. Jaspard, B., Couffinhal, T., Dufourcq, P., Moreau, C., and Duplaa, C. (2000). Expression pattern of mouse sFRP-1 and mWnt-8 gene during heart morphogenesis. Mech. Dev. 90, 263-267.
17. Kao, L.C., Tulac, S., Lobo, S., Imani, B., Yang, J.P., Germeyer, A., Osteen, K., Taylor, R.N., Lessey, B.A., and Giudice, L.C. (2002). Global gene profiling in human endometrium during the window of implantation. Endocrinology 143, 2119-2138.
18. Katoh, M. (2001). Molecular cloning and characterization of MFRP, a novel gene encoding a membrane-type Frizzled-related protein. Biochem. Biophys. Res. Commun. 282, 116-123.
19. Kikuchi, A. (2000). Regulation of β-catenin signaling in the Wnt pathway. Biochem. Biophys. Res. Commun. 268, 243-248.
20. Ladher, R.K., Church, V.L., Allen, S., Robson, L., Abdelfattah, A., Brown, N.A., Hattersley, G., Rosen, V., Luyten, F.P., Dale, L. and Francis-West, P.H. (2000). Cloning and expression of the Wnt antagonists Sfrp-2 and Frzb during chick development. Dev. Biol. 218, 183-198.
21. Leimeister, C., Bach, A., and Gessler, M. (1998). Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family. Mech. Dev. 75, 29-42.
22. Lo, M.L. (2001). A possible role for the WNT-1 pathway in oral carcinogenesis. Crit. Rev. Oral Biol. Med. 12, 152-165.
23. Marvin, M.J., Di Rocco, G., Gardiner, A., Bush, S.M., and Lassar, A.B. (2001). Inhibition of Wnt activity induces heart formation from posterior mesoderm. Genes Dev. 15, 316-327.
24. Nusse, R. and Varmus, H.E. (1992). Wnt Genes. Cell 69, 1073-1087.
25. Preiherr, J., Hildebrandt, T., Klostermann, S., Eberhardt, S., Kaul, S., and Weidle, U.H. (2000). Transcriptional profiling of human mammary carcinoma cell lines reveals PKW, a new tumor-specific gene. Anticancer Res. 20, 2255-2264.
26. Rattner, A., Hsieh, J.C., Smallwood, P.M., Gilbert, D.J., Copeland, N.G., Jenkins, N.A., and Nathans, J. (1997). A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc. Natl. Acad. Sci. USA 94, 2859-2863.
27. Roth, W., Wild-Bode, C., Platten, M., Grimmel, C., Melkonyan, H.S., Dichgans, J., and Weller, M. (2000). Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells. Oncogene 19, 4210-4220.
28. Sarkar, L., and Sharpe, P.T. (2000). Inhibition of Wnt signaling by exogenous Mfrzb1 protein affects molar tooth size. J. Dent. Res. 79, 920-925.
29. Schoenherr, C.J., and Anderson, D.J. (1995). The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes. Science 267, 1360-1363.
30. Schoenherr, C.J., Paquette, A.J., and Anderson, D.J. (1996). Identification of potential target genes for the neuron-restrictive silencer factor. Proc. Natl. Acad. Sci. USA 93, 9881-9886.
31. Smalley, M.J., and Dale, T.C. (2001). Wnt signaling and mammary tumorigenesis. J. Mammary Gland Biol. Neoplasia 6, 37-52.
32. Ugolini, F., Adélaïde, J., Charafe-Jauffret, E., Nguyen, C., Jacquemier, J., Jordan, B., Birnbaum, D., and Pébusque, M.J. (1999). Differential expression assay of chromosome arm 8p genes identifies frizzled-related (FRP1/FRZB) and fibroblast growth factor receptor 1 (FGFR1) as candidate breast cancer genes. Oncogene 18, 1903-1910.
33. Ugolini, F., Charafe-Jauffret, E., Bardou, V.J., Geneix, J., Adelaide, J., Labat-Moleur, F., Penault-Llorca, F., Longy, M., Jacquemier, J., Birnbaum, D., and Pebusque, M.J. (2001). WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type. Oncogene 20, 5810-5817.
34. Uren, A., Reichsman, F., Anset, V., Taylor, W.G., Muraiso, K., Bottaro, D.P., Cumberledge, S., and Rubin, J.S. (2000). Secreted frizzled-related protein-1 binds directly to wingless and is a biphasic modulator of wnt signaling. J. Biol. Chem. 275, 4374-4382.
35. Wada, N., Kawakami, Y., Ladher, R., Francis-West, P.H., and Nohno, T. (1999). Involvement of Frzb-1 in mesenchymal condensation and cartilage differentiation in the chick limb bud. Int. J. Dev. Biol. 43, 495-500.
36. Wang, Y., Macke, J.P., Abella, B.S., Andreasson, K., Worley, P., Gilbert, D.J., Copeland, N.G., Jenkins, N.A., and Nathans, J. (1996). A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled J. Biol. Chem. 271, 4468-4476.
37. Wolf, V., Ke, G., Dharmarajan, A.M., Bielke, W., Artuso, L., Saurer, S., and Friis, R. (1997). DDC-4, an apoptosis-associated gene, is a secreted frizzled relative. FEBS Lett. 417, 385-389.
38. Wong, S.C., Lo, S.F, Lee, K.C., Yam, J.W., Chan, J.K., and Hsiao, W.L.W. (2002). Expression of frizzled-related protein and Wnt-signaling molecules in invasive human breast tumors. J. Pathol. 196, 145-153.
39. val135. Biochem. Biophy. Res. Commun. 266, 472-480.
40. Yam, J.W.P., Chan, K.W., Wong, V.K.W., and Hsiao, W.L.W. (2001). Transcriptional activity of the promoter region of rat frizzled-related protein gene. Biochem. Biophys. Res. Commun. 286, 94-100.
41. Yang-Synder, J., Miller, J.R., Brown, J.D., Lai, C.J., and Moon, R.T. (1996). A frizzled homolog functions in a vertebrate Wnt signaling pathway. Curr. Biol. 6, 1302-1306.
42. Yoshino, K., Rubin, J.S., Higinbotham, K.G., Uren, A., Anest, V., Plisov, S.Y, and Perantoni, A.O. (2001). Secreted Frizzled-related proteins can regulate metanephric development. Mech. Dev. 102, 45-55.
43. Zhou, Z., Wang, J., Han, X., Zhou, J., and Linder, S. (1998). Upregulation of human secreted frizzled homolog in apoptosis and its down-regulation in breast tumors. Int. J. Cancer 78, 95-99.