CD28 costimulation independence of target organ versus circulating memory antigen-specific CD4+ T cells

Journal of Clinical Investigation

Volumn 112, Issue 5, 2003, Pages 776-784

  Fontenot, Andrew P ^a   Gharavi, Laia ^a   Bennett, Sean R ^a   Canavera, Scott J ^a   Newman, Lee S ^a,b   Kotzin, Brian L ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; GAMMA INTERFERON; MESSENGER RNA; ABATACEPT; ANTIBODY CONJUGATE; INTERLEUKIN 2;

ANTIGEN SPECIFICITY; ARTICLE; BERYLLIOSIS; CELL PROLIFERATION; CLINICAL ARTICLE; CYTOKINE RELEASE; HUMAN; MEMORY CELL; PHENOTYPE; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; APOPTOSIS; BIOSYNTHESIS; BLOOD; CD4+ T LYMPHOCYTE; CHRONIC DISEASE; COMPARATIVE STUDY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PHYSIOLOGY;

ANTIGENS, CD28; APOPTOSIS; BERYLLIOSIS; CD4-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; HUMANS; IMMUNOCONJUGATES; IMMUNOLOGIC MEMORY; INTERFERON TYPE II; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION;

EID: 0141611998     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200318317     Document Type: Article

References (50)

1. Bretscher, P., and Cohn, M. 1970. A theory of self-nonself discrimination. Science. 169:1042-1049.
2. Bluestone, J.A. 1995. New perspectives of CD28-B7-mediated T cell costimulation. Immunity. 2:555-559.
3. Harding, F.A., McArthur, J.G., Gross, J.A., Raulet, D.H., and Allison, J.P. 1992. CD28-mediated signaling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature. 356:607-609.
4. Schwartz, R.H. 1990. A cell culture model for T lymphocyte clonal anergy. Science. 248:1349-1356.
5. Liu, Y., and Janeway, C.A., Jr. 1992. Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells. Proc. Natl. Acad. Sci. U. S. A. 89:3845-3849.
6. Croft, M., Bradley, L.M., and Swain, S.L. 1994. Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells. J. Immunol. 152:2675-2685.
7. Garcia, S., DiSanto, J., and Stockinger, B. 1999. Following the development of a CD4 T cell response in vivo: from activation to memory formation. Immunity. 11:163-171.
8. London, C.A., Lodge, M.P., and Abbas, A.K. 2000. Functional responses and costimulator dependence of memory CD4+ T cells. J. Immunol. 164:265-272.
9. + T cells in patients with chronic beryllium disease. J. Clin. Invest. 110:1473-1482. doi:10.1172/JCI200215846.
10. Fontenot, A.P., Newman, L.S., and Kotzin, B.L. 2001. Chronic beryllium disease: T cell recognition of a metal presented by HLA-DP. Clin. Immunol. 100:4-14.
11. Newman, L.S., Maier, L.A., and Nemery, B. 1998. Interstitial lung disorders due to beryllium and cobalt. In Interstitial lung disease. 3rd edition. M.I. Schwarz and T.E. King, Jr., editors. B.C. Decker Inc Hamilton, Ontario, Canada. 367-392.
12. + T cells underlies disease susceptibility HLA-DP alleles in chronic beryllium disease. Proc. Natl. Acad. Sci. U. S. A. 97:12717-12722.
13. Kreiss, K., Wasserman, S., Mroz, M.M., and Newman, L.S. 1993. Beryllium disease screening in the ceramics industry: blood test performance and exposure-disease relations. J. Occup. Med. 35:267-274.
14. Kreiss, K., Mroz, M.M., Zhen, B., Martyny, J.W., and Newman, L.S. 1993. Epidemiology of beryllium sensitization and disease in nuclear workers. Am. Rev. Respir. Dis. 148:985-991.
15. Richeldi, L., et al. 1997. Interaction of genetic and exposure factors in the prevalence of berylliosis. Am. J. Ind. Med. 32:337-340.
16. Wang, Z., et al. 1999. Differential susceptibilities to chronic beryllium disease contributed by different Glu69 HLA-DPB1 and -DPA1 alleles. J. Immunol. 163:1647-1653.
17. Newman, L.S., and Kreiss, K. 1992. Nonoccupational beryllium disease masquerading as sarcoidosis: identification by blood lymphocyte proliferation response to beryllium. Am. Rev. Respir. Dis. 145:1212-1214.
18. Newman, L.S., Rose, C.S., and Maier, L.A. 1997. Sarcoidosis. N. Engl. J. Med. 336:1224-1234.
19. Rossman, M.D., et al. 1988. Proliferative response of bronchoalveolar lymphocytes to beryllium. Ann. Intern. Med. 108:687-693.
20. Saltini, C., Winestock, K., Kirby, M., Pinkston, P., and Crystal, R.G. 1989. Maintenance of alveolitis in patients with chronic beryllium disease by beryllium-specific helper T cells. N. Engl. Med. 320:1103-1109.
21. Kreiss, K., Newman, L.S., Mroz, M., and Campbell, P.A. 1989. Screening blood test identifies subclinical beryllium disease. J. Occup. Med. 31:603-608.
22. Mroz, M.M., Kreiss, K., Lezotte, D.C., Campbell, P.A., and Newman, L.S. 1991. Reexamination of the blood lymphocyte transformation test in the diagnosis of chronic beryllium disease. J. Allergy Clin. Immunol. 88:54-60.
23. Tinkle, S.S., Kittle, L.A., Schumacher, B.A., and Newman, L.S. 1997. Beryllium induces IL-2 and IFN-γ in berylliosis. J. Immunol. 158:518-526.
24. Fontenot, A.P., Kotzin, B.L., Comment, C., and Newman, L.S. 1998. Expansions of T-cell subsets expressing particular T cell receptor variable regions in chronic beryllium disease. Am. J. Respir. Cell Mol. Biol. 18:581-589.
25. Fontenot, A.P., Falta, M.T., Freed, B.M., Newman, L.S., and Kotzin, B.L. 1999. Identification of pathogenic T cells in patients with beryllium-induced lung disease. J. Immunol. 163:1619-1026.
26. Fontenot, A.P., et al. 2002. Beryllium skin patch resting to analyze T cell stimulation and granulomatous inflammation in the lung. J. Immunol. 168:3627-3634.
27. Lyons, A.B., and Parish, C.R. 1994. Determination of lymphocyte division by flow cytometry. J. Immunol. Methods. 171:131-137.
28. Chamberlain, W.D., Falta, M.T., and Kotzin, B.L. 2000. Functional subsets within clonally expanded CD8(+) memory T cells in elderly humans. Clin. Immunol. 94:160-172.
29. Lovett-Racke, A.E., et al. 1998. Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells. J. Clin. Invest. 101:725-730.
30. Markovic-Plese, S., Cortese, I., Wandinger, K.P., McFarland, H.F., and Martin, R. 2001. CD4+CD28-costimulation-independent T cells in multiple sclerosis. J. Clin. Invest. 108:1185-1194. doi:10.1172/JCI200112516.
31. Schmidt, D., Goronzy, J.J., and Weyand, C.M. 1996. CD4+ CD7- CD28- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. J. Clin. Invest. 97:2027-2037.
32. Haffar, O.K., et al. 1993. Costimulation of T-cell activation and virus production by B7 antigen on activated CD4+ T cells from human immunodeficiency virus type 1-infected donors. Proc. Natl. Acad. Sci. U. S. A. 90:11094-11098.
33. Martens, P.B., Goronzy, J.J., Schaid, D., and Weyand, C.M. 1997. Expansion of unusual CD4+ T cells in severe rheumatoid arthritis. Arthritis Rheum. 40:1106-1114.
34. Gimmi, C.D., et al. 1991. B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin-2. Proc. Natl. Acad. Sci. U. S. A. 88:6575-6579.
35. Jenkins, M.K., Taylor, P.S., Norton, S.D., and Urdahl, K.B. 1991. CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells. J. Immunol. 147:2461-2466.
36. Lombardi, G., et al. 2001. HLA-DP allele-specific T cell responses to beryllium account for DP-associated susceptibility to chronic beryllium disease. J. Immunol. 166:3549-3555.
37. Katchar, K., Wahlstrom, J., Eklund, A., and Grunewald, J. 2001. Highly activated T-cell receptor AV2S3(+) CD4(+) lung T-cell expansions in pulmonary sarcoidosis. Am. J. Respir. Crit. Care Med. 163:1540-1545.
38. Vallejo, A.N., Nestel, A.R., Schirmer, M., Weyand, C.M., and Goronzy, J.J. 1998. Aging-related deficiency of CD28 expression in CD4+ T cells is associated with the loss of gene-specific nuclear factor binding activity. J. Biol. Chem. 273:8119-8129.
39. Vallejo, A.N., et al. 2002. Molecular basis for the loss of CD28 expression in senescent cells. J. Biol. Chem. 277:46940-46949.
40. Bryl, E., Vallejo, A.N., Weyand, C.M., and Goronzy, J.J. 2001. Down-regulation of CD28 expression by TNF-alpha. J. Immunol. 167:3231-3238.
41. Posnett, D.N., Sinha, R., Kabak, S., and Russo, C. 1994. Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy". J. Exp. Med. 179:609-618.
42. Azuma, M., Phillips, J.H., and Lanier, L.L. 1993. CD28- T lymphocytes. Antigenic and functional properties. J. Immunol. 150:1147-1159.
43. + T cell expansions in normal individuals and patients with rheumatoid arthritis. J. Immunol. 154:3538-3547.
44. Weekes, M.P., Carmichael, A.J., Wills, M.R., Mynard, K., and Sissons, J.G. 1999. Human CD28-CD8+ T cells contain greatly expanded functional virus-specific memory CTL clones. J. Immunol. 162:7569-7577.
45. + T cells vary in differentiation phenotype in different persistent virus infections. Nat. Med. 8:379-385.
46. Boise, L.H., et al. 1995. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity. 3:87-98.
47. Frauwirth, K.A., et al. 2002. The CD28 signaling pathway regulates glucose metabolism. Immunity. 16:769-777.
48. Lenschow, D.J., Walunas, T.L., and Bluestone, J.A. 1996. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 14:233-258.
49. Salomon, B., and Bluestone, J.A. 2001. Complexities of CD28/B7: CTLA-4 costimulatory pathways in auroimmunity and transplantation. Annu. Rev. Immunol. 19:225-252.
50. Viglietta, V., Kent, S.C., Orban, T., and Hafler, D.A. 2002. GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes. J. Clin. Invest. 109:895-903. doi:10.1172/JCI200214114.