Mechanism of allorecognition and skin graft rejection in CD28 and CD40 ligand double-deficient mice

Transplantation

Volumn 76, Issue 5, 2003, Pages 854-858

  Habiro, Katsuyoshi ^a   Kotani, Motoko ^a   Omoto, Kazuya ^b   Kobayashi, Sakiko ^a,b   Tanabe, Kazunari ^b   Shimmura, Hiroaki ^b   Suzuki, Keiko ^a   Hayashi, Tomohito ^a   Toma, Hiroshi ^b   Abe, Ryo ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CD28 ANTIGEN; CD40 LIGAND; CD8 ANTIGEN;

ALLOGRAFT; ANIMAL CELL; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOLOGICAL TOLERANCE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; SKIN GRAFT; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD28; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; GRAFT REJECTION; LYMPHOCYTE CULTURE TEST, MIXED; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; SKIN TRANSPLANTATION; T-LYMPHOCYTES, CYTOTOXIC; TRANSPLANTATION, HOMOLOGOUS;

EID: 0141590407     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000084868.09385.83     Document Type: Article

References (30)

1. Alegre M, Fallarino F, Zhou P, et al. Transplantation and the CD28/CTLA4/B7 pathway. Transplant Proc 2001; 33(1-2): 209.
2. Witzke O, Barbara JA, Wood KJ. Induction of tolerance to alloantigen. Rev Immunogenet 1999; 1(3): 374.
3. Turka LA, Linsley PS, Lin H, et al. T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo. Proc Natl Acad Sci U S A 1992; 89(22): 11102.
4. Pearson TC, Alexander DZ, Winn KJ, et al. Transplantation tolerance induced by CTLA4-Ig. Transplantation 1994; 57(12): 1701.
5. Larsen CP, Alexander DZ, Hollenbaugh D, et al. CD40-gp39 interactions play a critical role during allograft rejection. Suppression of allograft rejection by blockade of the CD40-gp39 pathway. Transplantation 1996; 61(1): 4.
6. Larsen CP, Elwood ET, Alexander DZ, et al. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature 1996; 381(6581): 434.
7. Khoury S, Sayegh MH, Turka LA. Blocking costimulatory signals to induce transplantation tolerance and prevent autoimmune disease. Int Rev Immunol 1999; 18(3): 185.
8. Shimizu K, Schonbeck U, Mach F, et al. Host CD40 ligand deficiency induces long-term allograft survival and donor-specific tolerance in mouse cardiac transplantation but does not prevent graft arteriosclerosis. J Immunol 2000; 165(6): 3506.
9. Trambley J, Bingaman AW, Lin A, et al. Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection. J Clin Invest 1999; 104(12): 1715.
10. Guo Z, Meng L, Kim O, et al. CD8 T cell-mediated rejection of intestinal allografts is resistant to inhibition of the CD40/CD154 costimulatory pathway. Transplantation 2001; 71(9): 1351.
11. Williams MA, Trambley J, Ha J, et al. Genetic characterization of strain differences in the ability to mediate CD40/CD28-independent rejection of skin allografts. J Immunol 2000; 165(12): 6849.
12. Lane P, Gerhard W, Hubele S, et al. Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human gamma 1. Immunology 1993; 80(1): 56.
13. Murakami S, Miyake K, Abe R, et al. Characterization of autoantibody-secreting B cells in mice undergoing stimulatory (chronic) graft-versus-host reactions. Identification of a CD44hi population that binds specifically to hyaluronate. J Immunol 1991; 146(5): 1422.
14. Abe R, Ryan JJ, Finkelman FD, et al. T cell recognition of Mls. T cell clones demonstrate polymorphism between Mlsa, Mlsc, and Mlsd. J Immunol 1987; 138(2): 373.
15. Kubo M, Yamashita M, Abe R, et al. CD28 costimulation accelerates IL-4 receptor sensitivity and IL-4-mediated Th2 differentiation. J Immunol 1999; 163(5): 2432.
16. Punt JA, Havran W, Abe R, et al. T cell receptor (TCR)-induced death of immature CD4+CD8+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: implications for negative selection in the thymus. J Exp Med 1997; 186(11): 1911.
17. Benichou G, Takizawa PA, Olson CA, et al. Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection. J Exp Med 1992; 175(1): 305.
18. Fangmann J, Dalchau R, Fabre JW. Rejection of skin allografts by indirect allorecognition of donor class I major histocompatibility complex peptides. J Exp Med 1992; 175(6): 1521.
19. Liu Z, Braunstein NS, Suciu-Foca N. T cell recognition of allopeptides in context of syngeneic MHC. J Immunol 1992; 148(1): 35.
20. Benichou G, Valujskikh A, Heeger PS. Contributions of direct and indirect T cell alloreactivity during allograft rejection in mice. J Immunol 1999; 162(1): 352.
21. Bennett SR, Carbone FR, Karamalis F, et al. Help for cytotoxic-T-cell responses is mediated by CD40 signaling. Nature 1998; 393(6684): 478.
22. Ridge JP, Di Rosa F, Matzinger P. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature 1998; 393(6684): 474.
23. Schoenberger SP, Toes RE, van der Voort EI, et al. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 1998; 393(6684): 480.
24. Borrow P, Tishon A, Lee S, et al. CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response. J Exp Med 1996; 183(5): 2129.
25. Hu HM, Winter H, Ma J, et al. CD28, TNF receptor, and IL-12 are critical for CD4-independent cross-priming of therapeutic antitumor CD8+ T cells. J Immunol 2002; 169(9): 4897.
26. Hertz CJ, Kiertscher SM, Godowski PJ, et al. Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2. J Immunol 2001; 166(4): 2444.
27. Regnault A, Lankar D, Lacabanne V, et al. Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization. J Exp Med 1999; 189(2): 371.
28. Kreisel D, Krupnick AS, Gelman AE, et al. Non-hematopoietic allograft cells directly activate CD8+ T cells and trigger acute rejection: an alternative mechanism of allorecognition. Nat Med 2002; 8(3): 233.
29. Kreisel D, Krupnick AS, Balsara KR, et al. Mouse vascular endothelium activates CD8+ T lymphocytes in a B7-dependent fashion. J Immunol 2002; 169(11): 6154.
30. Merad M, Manz MG, Karsunky H, et al. Langerhans cells renew in the skin throughout life under steady-state conditions. Nat Immunol 2002; 3(12): 1135.