Procedure for immunocytochemical detection of P16INK4a antigen in thin-layer, liquid-based specimens

Acta Cytologica

Volumn 46, Issue 1, 2002, Pages 25-29

  Bibbo, Marluce ^a   Klump, William J ^a   DeCecco, Jennifer ^a   Kovatich, Albert J ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Cervical neoplasms; Immunocytochemistry; Liquid based cytology; P16 antibody; Papillomavirus, human

Indexed keywords

ANTIBODY; BUFFER; FORMALDEHYDE; P16 ANTIBODY; PARAFFIN; PEROXIDASE; PROTEIN P16; UNCLASSIFIED DRUG;

ANTIGEN DETECTION; ARTICLE; BIOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; COOLING; CYTOLOGY; DYSPLASIA; EPITHELIUM CELL; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOASSAY; IMMUNOCYTOCHEMISTRY; INFLAMMATORY CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REHYDRATION; SQUAMOUS CELL; TEMPERATURE DEPENDENCE; THIN LAYER CHROMATOGRAPHY; TUMOR CELL; UTERINE CERVIX; UTERINE CERVIX CARCINOMA;

BROSIMUM ALICASTRUM ALICASTRUM; PAPILLOMAVIRUS;

EID: 0036151974     PISSN: 00015547     EISSN: 19382650     Source Type: Journal    
DOI: 10.1159/000326711     Document Type: Article

References (10)

1. Absence of P15INK4B and P16INK4A gene alterations in primary cervical carcinoma tissues and cell lines with human papillomavirus infection
2. Underexpression of cyclin-dependent kinase (CDK) inhibitors in cervical carcinoma
3. 16INK4A as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri
4. 16INK4A, but not constitutively active pRb, can impose a sustained GI arrest: Molecular mechanisms and implications for oncogenesis
5. Alteration of p16 and p15 genes in human uterine tumours
6. In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis
7. Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions
8. Inter-observer reproducibility of cervical cytologic and histologic interpretations: Realistic estimates from the ASCUS-LSIL Triage Study (ALTS)
9. Cyclin E expression and early cervical neoplasia in ThinPrep specimens
10. P16INK4A and P15INK4B alterations in primary gynecologic malignancy