Effects of the substitution of Phe4 in the opioid peptide [D-Ala8]dynorphin A-(1-11)NH2

Journal of Medicinal Chemistry

Volumn 46, Issue 19, 2003, Pages 4002-4008

  Vig, Balvinder S ^a,e   Zheng, Mike Q ^a,f   Murray, Thomas F ^b   Aldrich, Jane V ^c,d  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c UNIVERSITY OF KANSAS   (United States)

^d UNIVERSITY OF KANSAS   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

^f UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,4 TETRAHYDROISOQUINOLINE 3 CARBOXYLIC ACID; 2 AMINOINDAN 2 CARBOXYLIC ACID DERIVATIVE; 2 AMINOTETRALIN 2 CARBOXYLIC ACID DERIVATIVE; ADENYLATE CYCLASE; ALPHA METHYLPHENYLALANINE; DYNORPHIN A [1-11][8 DEXTRO ALANINAMIDE]; DYNORPHIN A DERIVATIVE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; MU OPIATE RECEPTOR; N METHYLPHENYLALANINE; PHENYLALANINE DERIVATIVE; RADIOLIGAND; SIGMA OPIATE RECEPTOR; UNCLASSIFIED DRUG; ALANINE; DRUG DERIVATIVE; DYNORPHIN; FORSKOLIN; OPIATE RECEPTOR; PHENYLALANINE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG CONFORMATION; DRUG SYNTHESIS; LIGAND BINDING; MOLECULAR MODEL; NONHUMAN; RECEPTOR AFFINITY; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME SPECIFICITY; GENETICS; HAMSTER; ISOMERISM; METABOLISM; MOLECULAR CLONING; PROTEIN CONFORMATION; RADIOASSAY; RAT; SYNTHESIS;

ADENYLATE CYCLASE; ALANINE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; DYNORPHINS; FORSKOLIN; ISOMERISM; MODELS, MOLECULAR; PHENYLALANINE; PROTEIN CONFORMATION; RADIOLIGAND ASSAY; RATS; RECEPTORS, OPIOID; SUBSTRATE SPECIFICITY;

EID: 0141567464     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030075o     Document Type: Article

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