Synthesis and prostaglandin synthase inhibitory activity of new aromatic O-alkyloxime ethers substituted with methylsulfonamido or methylsulfonyl groups on their aliphatic portion

Farmaco

Volumn 58, Issue 9, 2003, Pages 707-714

  Balsamo, Aldo ^a   Mancini, Francesca ^b   Milanese, Claudio ^b   Orlandini, Elisabetta ^a   Ortore, Gabriella ^a   Pinza, Mario ^b   Rapposelli, Simona ^a   Rossello, Armando ^a  

^a UNIVERSITY OF PISA   (Italy)

^b Piazzale della Stazione SNC   (Italy)

Author keywords

Anti inflammatory drugs; Ciclooxygenase inhibitors; Methylsulfonamido inhibitors; Methylsulfonyl inhibitors; NSAIDs

Indexed keywords

2 (4 FLUOROBENZYLIDENEAMINOXY)ETHYL METHANESULFONAMIDE; ALKYL ETHER; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROGEN BOND; IC 50; MOUSE; NONHUMAN;

EID: 0141564721     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(03)00110-1     Document Type: Article

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