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Volumn 37, Issue 7, 2002, Pages 585-594
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Aryl-substituted methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: Effects of some structural modifications on their biological properties
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Author keywords
(E) (2 aryl 1 cyclopentenyl 1 alkylidene)(arylmethyloxy)amine; (E) 2 aryl 1 cyclopentenylmethyloxy) (benzylidene)amine; Antiinflammatory drug; Aryl substituted methyleneaminoxymethyl moiety; COX 2 inhibitor
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Indexed keywords
1 (BENZYLIDENEIMINOXYMETHYL) 2 (4 METHYLSULFINYLPHENYL)CYCLOPENTENE;
1 (BENZYLIDENEIMINOXYMETHYL) 2 (4 METHYLSULFONYLPHENYL)CYCLOPENTENE;
2 (4 AMINOSULFONYLMETHYL) 1 (METHYLOXYIMINOMETHYL)CYCLOPENTENE;
2 (4 METHYLSULFINYLPHENYL) 1 (METHYLOXYIMINOMETHYL)CYCLOPENTENE;
ANTIINFLAMMATORY AGENT;
CARRAGEENAN;
CYCLOOXYGENASE 1;
CYCLOOXYGENASE 2;
CYCLOOXYGENASE 2 INHIBITOR;
METHYL GROUP;
PROSTAGLANDIN E2;
UNCLASSIFIED DRUG;
CYCLOPENTANE DERIVATIVE;
ISOENZYME;
MEMBRANE PROTEIN;
PROSTAGLANDIN SYNTHASE;
PROSTAGLANDIN SYNTHASE INHIBITOR;
PTGS1 PROTEIN, HUMAN;
PTGS1 PROTEIN, RAT;
PTGS2 PROTEIN, HUMAN;
ANIMAL CELL;
ANIMAL EXPERIMENT;
ANTIINFLAMMATORY ACTIVITY;
ARTICLE;
CONTROLLED STUDY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
EDEMA;
ENZYME INHIBITION;
HUMAN;
HUMAN CELL;
MACROPHAGE ACTIVATION;
MOUSE;
NONHUMAN;
PAW EDEMA;
PROTEIN SYNTHESIS;
RAT;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
ANIMAL;
BIOSYNTHESIS;
CELL LINE;
CELL STRAIN U937;
CHEMISTRY;
DRUG ANTAGONISM;
IC 50;
INFLAMMATION;
ORAL DRUG ADMINISTRATION;
SYNTHESIS;
ADMINISTRATION, ORAL;
ANIMALS;
CELL LINE;
CYCLOOXYGENASE 1;
CYCLOOXYGENASE 2;
CYCLOOXYGENASE 2 INHIBITORS;
CYCLOOXYGENASE INHIBITORS;
CYCLOPENTANES;
DINOPROSTONE;
EDEMA;
HUMANS;
INFLAMMATION;
INHIBITORY CONCENTRATION 50;
ISOENZYMES;
MEMBRANE PROTEINS;
PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;
RATS;
STRUCTURE-ACTIVITY RELATIONSHIP;
U937 CELLS;
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EID: 0037046866
PISSN: 02235234
EISSN: None
Source Type: Journal
DOI: 10.1016/S0223-5234(02)01385-5 Document Type: Article |
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Times cited : (7)
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References (24)
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