CVT-124, a Novel Adenosine A-, Receptor Antagonist with Unique Diuretic Activity

Journal of Pharmacology and Experimental Therapeutics

Volumn 286, Issue 3, 1998, Pages 1191-1196

  Gellai, Miklos ^a   Schreiner, George F ^a   Ruffolo, Robert R ^a   Fletcher, Tracey ^a   Dewolf, Robin ^a   Brooks, David P ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A1 RECEPTOR ANTAGONIST; FUROSEMIDE; HYDROCHLOROTHIAZIDE; NAXIFYLLINE; 1,3 DIPROPYL 8 (2 (5,6 EPOXY)NORBORNYL)XANTHINE; 1,3-DIPROPYL-8-(2-(5,6-EPOXY)NORBORNYL)XANTHINE; ADENOSINE RECEPTOR; DIURETIC AGENT; XANTHINE DERIVATIVE;

ARTICLE; DIURETIC ACTIVITY; DOSE RESPONSE; FLUID BALANCE; FLUID RETENTION; FREE WATER CLEARANCE; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; POTASSIUM EXCRETION; PRIORITY JOURNAL; RAT; SODIUM EXCRETION; URINE FLOW RATE; URINE OSMOLALITY; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; GLOMERULUS FILTRATION RATE; KIDNEY CIRCULATION; SPRAGUE DAWLEY RAT;

ANIMALS; DIURETICS; DOSE-RESPONSE RELATIONSHIP, DRUG; FUROSEMIDE; GLOMERULAR FILTRATION RATE; HYDROCHLOROTHIAZIDE; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P1; RENAL CIRCULATION; XANTHINES;

EID: 0032158694     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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