MZF6D, a novel KRAB zinc-finger gene expressed exclusively in meiotic male germ cells

DNA and Cell Biology

Volumn 22, Issue 8, 2003, Pages 489-496

  Looman, Camilla ^a   Mark, Charlotta ^a   Åbrink, Magnus ^b   Hellman, Lars ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ZINC FINGER PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE LOCATION; IN SITU HYBRIDIZATION; MALE; MEIOSIS; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REPRESSOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPERMATOCYTE; SPERMATOGENESIS; TISSUE SECTION; ZINC FINGER MOTIF;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; HUMANS; MALE; MEIOSIS; MICE; MOLECULAR SEQUENCE DATA; RATS; REPRESSOR PROTEINS; SPERMATOCYTES; SPERMATOGENESIS; TESTIS; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0141539424     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/10445490360708892     Document Type: Article

References (56)

1. ÅBRINK, M., AVESKOGH, M., and HELLMAN, L. (1995). Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937. DNA Cell Biol. 14, 125-136.
2. ABRINK, M., ORTIZ, J.A., MARK, C., SANCHEZ, C., LOOMAN, C., HELLMAN, L., CHAMBON, P., and LOSSON, R. (2001). Conserved interaction between distinct Kruppel-associated box domains and the transcriptional intermediary factor 1 beta. Proc. Natl. Acad. Sci. USA 98, 1422-1426.
3. AGATA, Y., MATSUDA, E., and SHIMIZU, A. (1999). Two novel Kruppel-associated box-containing zinc-finger proteins, KRAZ1 and KRAZ2, repress transcription through functional interaction with the corepressor KAP-1 (TIF1beta/KRIP-1). J. Biol. Chem. 274, 16412-16422.
4. BEHR, R., and KAESTNER, K.H. (2002). Developmental and cell type-specific expression of the zinc finger transcription factor Kruppel-like factor 4 (Klf4) in postnatal mouse testis. Mech. Dev. 115, 167-169.
5. BELLEFROID, E.J., LECOCQ, P.J., BENHIDA, A., PONCELET, D.A., BELAYEW, A., and MARTIAL, J.A. (1989). The human genome contains hundreds of genes coding for finger proteins of the Kruppel type. DNA 8, 377-387.
6. BELLEFROID, E.J., PONCELET, D.A., LECOCQ, P.J., REVELANT, O., and MARTIAL, J.A. (1991). The evolutionary conserved Kruppel-associated box domain defines a subfamily of eukaryotic multi-fingered proteins. Proc. Natl. Acad. Sci USA 88, 3608-3612.
7. BENGTSSON, H., SODERSTROM, S., KYLBERG, A., CHARETTE, M.F., and EBENDAL, T. (1998). Potentiating interactions between morphogenetic protein and neurotrophic factors in developing neurons. J. Neurosci. Res. 53, 559-568.
8. BONVENTRE, J.V., and WITZGALL, R. (1995). Kid-1, a kidney transcription factor. Exp. Nephrol. 3, 159-164.
9. BURKE, P.S., and WOLGEMUTH, D.J. (1992). Zfp-37, a new murine zinc finger encoding gene, is expressed in a developmentally regulated pattern in the male germ line. Nucleic Acids Res. 20, 2827-2834.
10. CHOWDHURY, K., GOULDING, M., WALTHER, C., IMAI, K., and FICKENSCHER, H. (1992). The ubiquitous transactivator Zfp-38 is upregulated during spermatogenesis with differential transcription. Mech. Dev. 39, 129-142.
11. CUNLIFFE, V., KOOPMAN, P., MCLAREN, A., and TROWSDALE, J. (1990). A mouse zinc finger gene which is transiently expressed during spermatogenesis. EMBO J. 9, 197-205.
12. DANG, D.T., PEVSNER, J., and YANG, V.W. (2000). The biology of the mammalian Kruppel-like family of transcription factors. Int. J. Biochem. Cell Biol. 32, 1103-1121.
13. DENNY, P., and ASHWORTH, A. (1991). A zinc finger protein-encoding gene expressed in the post-meiotic phase of spermatogenesis. Gene 106, 221-227.
14. DREYER, S.D., ZHENG, Q., ZABEL, B., WINTERPACHT, A., and LEE, B. (1999). Isolation, characterization, and mapping of a zinc finger gene, ZFP95, containing both a SCAN box and an alternatively spliced KRAB A domain. Genomics 62, 119-122.
15. FRIEDMAN, J.R., FREDERICKS, W.J., JENSEN, D.E., SPEICHER, D.W., HUANG, X.P., NEILSON, E.G., and RAUSCHER, F.J.R. (1996). KAP-1, a novel corepressor for the highly conserved KRAB repression domain. Genes Dev. 10, 2067-2078.
16. GANSS, B., and KOBAYASHI, H. (2002). The zinc finger transcription factor Zfp60 is a negative regulator of cartilage differentiation. J. Bone Miner. Res. 17, 2151-2160.
17. HECHT, N.B. (1998). Molecular mechanisms of male germ cell differentiation. Bioessays 20, 555-561.
18. HENNEMANN, H., VASSEN, L., GEISEN, C., EILERS, M., and MOROY, T. (2003). Identification of a novel KRAB box domain protein - KRIM-1 - that interacts with c-Myc and inhibits its oncogenic activity. J. Biol. Chem. 278, 28799-28811.
19. HOSSEINI, R., MARSH, P., PIZZEY, J., LEONARD, L., RUDDY, S., BAINS, S., and DUDLEY, K. (1994). Restricted expression of a zinc finger protein in male germ cells. J. Mol. Endocrinol. 13, 157-165.
20. JHEON, A.H., GANSS, B., CHEIFETZ, S., and SODEK, J. (2001). Characterization of a novel KRAB/C2H2 zinc finger transcription factor involved in bone development. J. Biol. Chem. 276, 18282-18289.
21. KIM, S.S., CHEN, Y.M., O'LEARY, E., WITZGALL, R., VIDAL, M., and BONVENTRE, J.V. (1996). A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins. Proc. Natl. Acad. Sci. USA 93, 15299-15304.
22. KLEENE, K.C. (2001). A possible meiotic function of the peculiar patterns of gene expression in mammalian spermatogenic cells. Mech. Dev. 106, 3-23.
23. LANDER, E.S., LINTON, L.M., BIRREN, B., et al. (2001). Initial sequencing and analysis of the human genome. Nature 409, 860-921.
24. LECHNER, M.S., BEGG, G.E., SPEICHER, D.W., and RAUSCHER, F.R. (2000). Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: Direct chromoshadow domain-KAP-1 corepressor interaction is essential. Mol. Cell. Biol. 20, 6449-6465.
25. LEE, P.L., GELBART, T., WEST, C., ADAMS, M., BLACKSTONE, R., and BEUTLER, E. (1997). Three genes encoding zinc finger proteins on human chromosome 6p21.3: Members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. Genomics 43, 191-201.
26. LOOMAN, C., HELLMAN, L., and ABRINK, M. (2004). A novel Krüppel-associated box identified in a panel of mammalian zinc finger proteins. Mammalian Genome 15, in press.
27. MALDONADO, E., HAMPSEY, M., and REINBERG, D. (1999). Repression: Targeting the heart of the matter. Cell 99, 455-458.
28. MARK, C., ABRINK, M., and HELLMAN, L. (1999). Comparative analysis of KRAB zinc finger proteins in rodents and man: Evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes. DNA Cell Biol. 18, 381-396.
29. MARK, C., LOOMAN, C., ABRINK, M., and HELLMAN, L. (2001). Molecular cloning and preliminary functional analysis of two novel human KRAB zinc finger proteins, HKr18 and HKr19. DNA Cell Biol. 20, 275-286.
30. MIZUTANI, T., YAMADA, K., YAZAWA, T., OKADA, T., MINEGISHI, T., and MIYAMOTO, K. (2001). Cloning and characterization of gonadotropin-inducible ovarian transcription factors (GIOT1 and -2) that are novel members of the (Cys)(2)-(His)(2)-type zinc finger protein family. Mol. Endocrinol. 15, 1693-1705.
31. MOOSMANN, P., GEORGIEV, O., LE DOUARIN, B., BOURQUIN, J.P., and SCHAFFNER, W. (1996). Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1. Nucleic Acids Res. 24, 4859-4867.
32. NAGAMINE, C.M., CHAN, K., HAKE, L.E., and LAU, Y.F. (1990). The two candidate testis-determining Y genes (Zfy-1 and Zfy-2) are differentially expressed in fetal and adult mouse tissues. Genes Dev. 4, 63-74.
33. NIELSEN, A.L., ORTIZ, J.A., YOU, J., OULAD, A.M., KHECHUMIAN, R., GANSMULLER, A., CHAMBON, P., and LOSSON, R. (1999). Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family. EMBO J. 18, 6385-6395.
34. NOCE, T., FUJIWARA, Y., ITO, M., TAKEUCHI, T., HASHIMOTO, N., YAMANOUCHI, M., HIGASHINAKAGAWA, T., and FUJIMOTO, H. (1993). A novel murine zinc finger gene mapped within the tw18 deletion region expresses in germ cells and embryonic nervous system. Dev. Biol. 155, 409-422.
35. NOCE, T., FUJIWARA, Y., SEZAKI, M., FUJIMOTO, H., and HIGASHINAKAGAWA, T. (1992). Expression of a mouse zinc finger protein gene in both spermatocytes and oocytes during meiosis. Dev. Biol. 153, 356-367.
36. OAKBERG, E. (1956). A description of spermiogenesis in the mouse and its use in analysis of the cycle of the seminiferous epithelium and germ cell renewal. Am. J. Anat. 99, 391-413.
37. PASSANANTI, C., CORBI, N., PAGGI, M.G., RUSSO, M.A., PEREZ, M., COTELLI, F., STEFANINI, M., and AMATI, P. (1995). The product of Zfp59 (Mfg2), a mouse gene expressed at the spermatid stage of spermatogenesis, accumulates in spermatozoa nuclei. Cell Growth Differ. 6, 1037-1044.
38. PONCELET, D.A., BELLEFROID, E.J., BASTIAENS, P.V., DEMOITIE, M.A., MARINE, J.C., PENDEVILLE, H., ALAMI, Y., DEVOS, N., LECOCQ, P., OGAWA, T., et al. (1998). Functional analysis of ZNF85 KRAB zinc finger protein, a member of the highly homologous ZNF91 family. DNA Cell Biol. 17, 931-943.
39. ROGERS, M.B., HOSLER, B.A., and GUDAS, L.J. (1991). Specific expression of a retinoic acid-regulated, zinc-finger gene, Rex-1, in preimplantation embryos, trophoblast and spermatocytes. Development 113, 815-824.
40. ROSATI, M., MARINO, M., FRANZE, A., TRAMONTANO, A., and GRIMALDI, G. (1991). Members of the zinc finger protein gene family sharing a conserved N-terminal module. Nucleic Acids Res. 19, 5661-5667.
41. RUE, S.W., KIM, B.W., JUN, D.Y., and KIM, Y.H. (2001). Nucleotide sequence and cell cycle-associated differential expression of ZF5128, a novel Kruppel type zinc finger protein gene. Biochim. Biophys. Acta 1522, 230-237.
42. RYAN, R.F., SCHULTZ, D.C., AYYANATHAN, K., SINGH, P.B., FRIEDMAN, J.R., FREDERICKS, W.J., and RAUSCHER, F.R. (1999). KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: A potential role for Kruppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing. Mol. Cell. Biol. 19, 4366-4378.
43. SANGER, F., NICLEN, S., and COULSON, A.R. (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
44. SCHULTZ, D.C., AYYANATHAN, K., NEGOREV, D., MAUL, G.G., and RAUSCHER, F.J., 3RD. (2002). SETDB1: A novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev. 16, 919-932.
45. SCHULTZ, D.C., FRIEDMAN, J.R., and RAUSCHER, F.J., 3RD. (2001). Targeting histone deacetylase complexes via KRAB-zinc finger proteins: The PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD. Genes Dev. 15, 428-443.
46. THOMPSON, J.D., HIGGINS, D.G., and GIBSON, T.J. (1994). CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22, 4673-4780.
47. TUPLER, R., PERINI, G., and GREEN, M.R. (2001). Expressing the human genome. Nature 409, 832-833.
48. UNDERHILL, C., QUTOB, M.S., YEE, S.P., and TORCHIA, J. (2000). A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1. J. Biol. Chem. 275, 40463-40470.
49. VENTER, J.C., ADAMS, M.D., MYERS, E.W., et al. (2001). The sequence of the human genome. Science 291, 1304-1351.
50. VISSING, H., MEYER, W.K., AAGAARD, L., TOMMERUP, N., and THIESEN, H.J. (1995). Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins. FEBS Lett. 369, 153-157.
51. WATSON, R.P., TEKKI, K.N., and BOULTER, C.A. (2000). Characterisation, chromosomal localisation and expression of the mouse Kid3 gene. Biochim. Biophys. Acta 1490, 153-158.
52. WEBER, P., CAMMAS, F., GERARD, C., METZGER, D., CHAMBON, P., LOSSON, R., and MARK, M. (2002). Germ cell expression of the transcriptional co-repressor TIF1beta is required for the maintenance of spermatogenesis in the mouse. Development 129, 2329-2337.
53. WITZGALL, R., OBERMULLER, N., BOLITZ, U., CALVET, J.P., COWLEY, B.J., WALKER, C., KRIZ, W., GRETZ, N., and BONVENTRE, J.V. (1998). Kid-1 expression is high in differentiated renal proximal tubule cells and suppressed in cyst epithelia. Am. J. Physiol. 275, F928-F937.
54. WITZGALL, R., O'LEARY, E., GESSNER. R., OUELLETTE, A.J., and BONVENTRE, J.V. (1993). Kid-1, a putative renal transcription factor: Regulation during ontogeny and in response to ischemia and toxic injury. Mol. Cell. Biol. 13, 1933-1942.
55. WU, H., ZHANG, S., QIU, W., ZHANG, G., XIA, Q., XIAO, C., HUANG, X., HUANG, M., AGEN, P., FAN, T., et al. (2001). Isolation, characterization, and mapping of a novel human KRAB zinc finger protein encoding gene ZNF463. Biochim. Biophys. Acta 1518, 190-193.
56. ZAWEL, L., KUMAR, K.P., and REINBERG, D. (1995). Recycling of the general transcription factors during RNA polymerase II transcription. Genes Dev. 9, 1479-1490.