Molecular cloning and preliminary functional analysis of two novel human KRAB zinc finger proteins, HKr18 and HKr19

DNA and Cell Biology

Volumn 20, Issue 5, 2001, Pages 275-286

  Mark, C ^a   Looman, C ^a   Abrink M ^a   Hellman, L ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ZINC FINGER PROTEIN;

ARTICLE; BONE MARROW CELL; CARBOXY TERMINAL SEQUENCE; CHROMOSOME 19; CHROMOSOME 7; CONTROLLED STUDY; DNA LIBRARY; DNA SEQUENCE; GENE SEQUENCE; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; LYMPHOID CELL; MALE; MOLECULAR CLONING; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN MOTIF; SEQUENCE HOMOLOGY; TESTIS; TISSUE DISTRIBUTION;

EID: 0034926247     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/104454901750232472     Document Type: Article

References (42)

1. Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937
2. Conserved interaction between distinct Kruppel-associated box domains and the transcriptional intermediary factor 1β
3. Two novel Krüppel-associated box-containing zinc-finger proteins, KRAZ1 and KRAZ2, repress transcription through functional interaction with the corepressor KAP-1 (TIF1beta/KRIP-1)
4. An integrated metric physical map of human chromosome 19
5. The human genome contains hundreds of genes coding for finger proteins of the Kruppel type
6. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells
7. The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins
8. The zinc finger protein NRIF interacts with the neurotrophin receptor p75 (NTR) and participates in programmed cell death
9. A cluster of related zinc finger protein genes is deleted in the mouse embryonic lethal mutation tw18
10. Transcription factors in hematopoiesis
11. KAP-1, a novel corepressor for the highly conserved KRAB repression domain
12. Mechanism for activation of mouse mast cell tryptase: Dependence on heparin and acidic pH for formation of active tetramers of mouse mast cell protease 6
13. High-resolution localization of 69 potential human zinc finger protein genes: A number are clustered
14. A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins
15. Developmentally regulated mouse gene NK10 encodes a zinc finger repressor protein with differential DNA-binding domains
16. A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors
17. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes
18. A gene encoding 22 highly related zinc fingers is expressed in lymphoid cell lines
19. Krüppel-associated boxes are potent transcriptional repression domains
20. Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci
21. Comparative analysis of KRAB zinc finger proteins in rodents and man: Evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes
22. Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family
23. Cloning and characterization of ZNF189, a novel human Krüppel-like zinc finger gene localized to chromosome 9q22-q31
24. Reconstitution of the KRAB-KAP-1 repressor complex: A model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein-protein interactions
25. Repression of transcriptional activity at a distance by the evolutionarily conserved KRAB domain present in a subfamily of zinc finger proteins
26. Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF
27. Functional analysis of ZNF85 KRAB zinc finger protein, a member of the highly homologous ZNF91 family
28. A KRAB zinc finger protein gene is the potential target of 19q13 translocation in benign thyroid tumors
29. Transcriptional regulation of lymphocyte lineage commitment
30. Chromosomal localization of 9 KOX zinc finger genes: Physical linkages suggest clustering of KOX genes on chromosomes 12, 16, and 19
31. KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: A potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing
32. DNA sequencing with chain-terminating inhibitors
33. Tandem zinc-finger gene families in mammals: Insights and unanswered questions
34. Analysis of homologous XRCC1-linked zinc-finger gene families in human and mouse: Evidence for orthologous genes
35. Cloning and characterization of a novel KrÜppel-associated box family transcriptional repressor that interacts with the retinoblastoma gene product, RB
36. A zinc-finger gene ZNF141 mapping at 4p16.3/D4S90 is a candidate gene for the Wolf-Hirschhorn (4p-) syndrome
37. Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders
38. Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells
39. A broad role for the zinc finger protein ZNF202 in human lipid metabolism
40. Characterisation, chromosomal localisation and expression of the mouse Kid3 gene
41. The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression
42. Identification and characterization of human ZNF274 cDNA, which encodes a novel Krüppel-type zinc-finger protein having nucleolar targeting ability