CCR5 antagonists: 3-(pyrrolidin-1-yl)propionic acid analogues with potent anti-HIV activity

Organic Letters

Volumn 5, Issue 14, 2003, Pages 2473-2475

  Lynch, Christopher L ^a   Hale, Jeffrey J ^a   Budhu, Richard J ^a   Gentry, Amy L ^a   Finke, Paul E ^a   Caldwell, Charles G ^a   Mills, Sander G ^a   MacCoss, Malcolm ^a   Shen, Dong Ming ^a   Chapman, Kevin T ^a   Malkowitz, Lorraine ^a   Springer, Martin S ^a   Gould, Sandra L ^a   DeMartino, Julie A ^a   Siciliano, Salvatore J ^a   Cascierl, Margaret A ^a   Carella, Anthony ^a   Carver, Gwen ^a   Holmes, Karen ^a   Schleif, William A ^a   Danzeisen, Renee ^a   Hazuda, Daria ^a   Kessler, Joseph ^a   Lineberger, Janet ^a   Miller, Michael ^a   Emini, Emilio ^a   more..

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (PYRROLIDIN 1 YL)PROPIONIC ACID; AMINO ACID DERIVATIVE; ANTIVIRUS AGENT; CHEMOKINE RECEPTOR CCR5; CYCLOPENTANE; CYCLOPENTANE 1; PROPIONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG POTENCY; DRUG SYNTHESIS; RECEPTOR AFFINITY;

ANTI-HIV AGENTS; BIOLOGICAL AVAILABILITY; PROPIONIC ACIDS; PYRROLIDINES; RECEPTORS, CCR5;

EID: 0141519691     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol034707c     Document Type: Article

References (10)

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