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Volumn 47, Issue 2, 2003, Pages 201-207

Axonal damage is reduced following glatiramer acetate treatment in C57/bl mice with chronic-induced experimental autoimmune encephalomyelitis

Author keywords

Axonal damage; Experimental autoimmune encephalomyelitis (EAE); Glatiramer acetate; Multiple sclerosis (MS); Myelin oligodendrocyte glycoprotein (MOG)

Indexed keywords

AMYLOID PRECURSOR PROTEIN; ANTIBODY; GLATIRAMER; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; NEUROFILAMENT PROTEIN;

EID: 0141516543     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(03)00217-7     Document Type: Article
Times cited : (73)

References (42)
  • 1
    • 0032476565 scopus 로고    scopus 로고
    • Bystander suppression of experimental autoimmune encephalomyelitis by T cell lines and clones of the Th2 type induced by copolymer 1
    • Aharoni R., Teitelbaum D., Sela M., et al. Bystander suppression of experimental autoimmune encephalomyelitis by T cell lines and clones of the Th2 type induced by copolymer 1. J. Neuroimmunol. 91:1998;135-146.
    • (1998) J. Neuroimmunol. , vol.91 , pp. 135-146
    • Aharoni, R.1    Teitelbaum, D.2    Sela, M.3
  • 2
    • 0344490328 scopus 로고    scopus 로고
    • Therapeutic vaccine for acute and chronic motor neuron diseases: Implications for aprocmyotrophic lateral sclerosis
    • Angelov D.N., Waibel S., Guantinas-Lichius O., et al. Therapeutic vaccine for acute and chronic motor neuron diseases: implications for aprocmyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. 100:2003;4790-4795.
    • (2003) Proc. Natl. Acad. Sci. , vol.100 , pp. 4790-4795
    • Angelov, D.N.1    Waibel, S.2    Guantinas-Lichius, O.3
  • 3
    • 0029986881 scopus 로고    scopus 로고
    • The autoimmune reactivity to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis is potentially pathogenic: Effect of copolymer 1 on MOG-induced disease
    • Ben-Nun A., Mendel I., Bakimer R., et al. The autoimmune reactivity to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis is potentially pathogenic: effect of copolymer 1 on MOG-induced disease. J. Neurol. 243:1996;S14-S22.
    • (1996) J. Neurol. , vol.243
    • Ben-Nun, A.1    Mendel, I.2    Bakimer, R.3
  • 4
    • 0000361150 scopus 로고
    • Histologie de la sclerose en plaque
    • Charcot M. Histologie de la sclerose en plaque. Gaz. Hosp. 41:1868;554-556.
    • (1868) Gaz. Hosp. , vol.41 , pp. 554-556
    • Charcot, M.1
  • 5
    • 0032852674 scopus 로고    scopus 로고
    • In vivo evidence for axonal dysfunction remote from focal cerebral demyelination of the type seen in multiple sclerosis
    • De Stefano N., Narayanan S., Matthews P.M., et al. In vivo evidence for axonal dysfunction remote from focal cerebral demyelination of the type seen in multiple sclerosis. Brain. 122:1999;1933-1939.
    • (1999) Brain , vol.122 , pp. 1933-1939
    • De Stefano, N.1    Narayanan, S.2    Matthews, P.M.3
  • 6
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • Ferguson B., Matyszak M.K., Esivi M.M. Axonal damage in acute multiple sclerosis lesions. Brain. 120:1997;292-299.
    • (1997) Brain , vol.120 , pp. 292-299
    • Ferguson, B.1    Matyszak, M.K.2    Esivi, M.M.3
  • 7
    • 0035964157 scopus 로고    scopus 로고
    • Glatiramer acetate reduces the proportion of new MS lesions evolving into "black holes"
    • Filippi M., Rovaris M., Rocca M.A., et al. Glatiramer acetate reduces the proportion of new MS lesions evolving into "black holes" Neurology. 57:2001;731-733.
    • (2001) Neurology , vol.57 , pp. 731-733
    • Filippi, M.1    Rovaris, M.2    Rocca, M.A.3
  • 8
    • 0028340163 scopus 로고
    • Direct binding of myelin basic protein and synthetic copolymer 1 to class II major histocompatibility complex molecules on living antigen-presenting cells: Specificity and promiscuity
    • Fridkis-Hareli M., Teitelbaum D., Gurevich E., et al. Direct binding of myelin basic protein and synthetic copolymer 1 to class II major histocompatibility complex molecules on living antigen-presenting cells: specificity and promiscuity. Proc. Natl. Acad. Sci. 91:1994;4872-4876.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 4872-4876
    • Fridkis-Hareli, M.1    Teitelbaum, D.2    Gurevich, E.3
  • 9
    • 0029082566 scopus 로고
    • Copolymer 1 reduces relapses rate and improves disability in relapsing-remitting multiple sclerosis: Results of a phase III multicenter, double blind, placebo-controlled trial
    • Johnson K.P., Brooks B.R., Cohen J.A., et al. Copolymer 1 reduces relapses rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double blind, placebo-controlled trial. Neurology. 45:1995;1268-1276.
    • (1995) Neurology , vol.45 , pp. 1268-1276
    • Johnson, K.P.1    Brooks, B.R.2    Cohen, J.A.3
  • 10
    • 6844254570 scopus 로고    scopus 로고
    • Extended use of glatiramer acetate (Copaxone) is well tolerated and maintains its clinical effect on multiple sclerosis relapse rate and degree of disability. Copolymer 1 Multiple Sclerosis Study Group
    • Johnson K.P., Brooks B.R., Cohen J.A., et al. Extended use of glatiramer acetate (Copaxone) is well tolerated and maintains its clinical effect on multiple sclerosis relapse rate and degree of disability. Copolymer 1 Multiple Sclerosis Study Group. Neurology. 50:1998;701-708.
    • (1998) Neurology , vol.50 , pp. 701-708
    • Johnson, K.P.1    Brooks, B.R.2    Cohen, J.A.3
  • 11
    • 0035956508 scopus 로고    scopus 로고
    • Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: Results of a phase III multicenter, double-blind, placebo-controlled trial
    • Johnson K.P., Brooks B.R., Cohen J.A., et al. Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind, placebo-controlled trial. Neurol. Suppl. 5:2001;S16-S24.
    • (2001) Neurol. Suppl. , vol.5
    • Johnson, K.P.1    Brooks, B.R.2    Cohen, J.A.3
  • 12
    • 0028965522 scopus 로고
    • Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG)-derived peptide: Preliminary analysis of MOG T cell epitopes
    • Kerlero de Rosbo N., Mendel I., Ben-Nun A. Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG)-derived peptide: preliminary analysis of MOG T cell epitopes. Eur. J. Immunol. 25:1995;985-993.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 985-993
    • Kerlero de Rosbo, N.1    Mendel, I.2    Ben-Nun, A.3
  • 13
    • 0034691136 scopus 로고    scopus 로고
    • T cell immunity to copolymer 1 confers neuroprotection on the damaged optic nerve: Possible therapy for optic neuropathies
    • Kipnis J., Yoles E., Porat Z., et al. T cell immunity to copolymer 1 confers neuroprotection on the damaged optic nerve: possible therapy for optic neuropathies. Proc. Natl. Acad. Sci. USA. 97:2000;7446-7451.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 7446-7451
    • Kipnis, J.1    Yoles, E.2    Porat, Z.3
  • 14
    • 0033870097 scopus 로고    scopus 로고
    • Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions
    • Kornek B., Storch M.K., Weissert R., et al. Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions. Am. J. Pathol. 157:2000;267-276.
    • (2000) Am. J. Pathol. , vol.157 , pp. 267-276
    • Kornek, B.1    Storch, M.K.2    Weissert, R.3
  • 15
    • 0000603927 scopus 로고    scopus 로고
    • Experimental models of multiple sclerosis
    • A. Compston, G. Ebers, H. Lassmann, I. McDonald, B. Matthews, & H. Wekerle. London, Edinburgh, New York: Churchill Livingstone
    • Lassmann H., Wekerle H. Experimental models of multiple sclerosis. Compston A., Ebers G., Lassmann H., McDonald I., Matthews B., Wekerle H. McAlpine's Multiple Sclerosis. 1998;409-433 Churchill Livingstone, London, Edinburgh, New York.
    • (1998) McAlpine's Multiple Sclerosis , pp. 409-433
    • Lassmann, H.1    Wekerle, H.2
  • 16
    • 0034996079 scopus 로고    scopus 로고
    • Glatiramer acetate inhibition of tumor necrosis factor α-induced RANTES expression and release from U-251 MG human astrocytic cells
    • Li Q.Q., Burt D.R., Bever T. Glatiramer acetate inhibition of tumor necrosis factor α-induced RANTES expression and release from U-251 MG human astrocytic cells. J. Neurochem. 77:2001;1208-1217.
    • (2001) J. Neurochem. , vol.77 , pp. 1208-1217
    • Li, Q.Q.1    Burt, D.R.2    Bever, T.3
  • 19
    • 0035865002 scopus 로고    scopus 로고
    • Demyelination and axonal damage in non-humans primate model of multiple sclerosis
    • Mancardi G., Hart B., Roccatagliata L., et al. Demyelination and axonal damage in non-humans primate model of multiple sclerosis. J. Neurol. Sci. 184:2001;41-49.
    • (2001) J. Neurol. Sci. , vol.184 , pp. 41-49
    • Mancardi, G.1    Hart, B.2    Roccatagliata, L.3
  • 20
    • 0031769822 scopus 로고    scopus 로고
    • Putting magnetic resonance spectroscopy studies in context: Axonal damage and disability in multiple sclerosis
    • Matthews P.M., De Stefano N., Narayanan S., et al. Putting magnetic resonance spectroscopy studies in context: axonal damage and disability in multiple sclerosis. Semin. Neurol. 18:1998;327-336.
    • (1998) Semin. Neurol. , vol.18 , pp. 327-336
    • Matthews, P.M.1    De Stefano, N.2    Narayanan, S.3
  • 21
    • 0031921636 scopus 로고    scopus 로고
    • Interleukin-6 functions in autoimmune encephalomyelitis: A study in gene-targeted mice
    • Mendel I., Katz A., Kozak N., et al. Interleukin-6 functions in autoimmune encephalomyelitis: a study in gene-targeted mice. Eur. J. Immunol. 28:1998;1727-1737.
    • (1998) Eur. J. Immunol , vol.28 , pp. 1727-1737
    • Mendel, I.1    Katz, A.2    Kozak, N.3
  • 22
    • 0035957307 scopus 로고    scopus 로고
    • Mechanisms of action of glatiramer acetate in multiple sclerosis
    • Neuhaus O., Farina C., Wekerl H., et al. Mechanisms of action of glatiramer acetate in multiple sclerosis. Neurology. 56:2001;702-708.
    • (2001) Neurology , vol.56 , pp. 702-708
    • Neuhaus, O.1    Farina, C.2    Wekerl, H.3
  • 24
    • 0034455884 scopus 로고    scopus 로고
    • Mice overexpressing Bcl-2 in their neurons are resistant to myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE)
    • Offen D., Kaye J.F., Bernard O., et al. Mice overexpressing Bcl-2 in their neurons are resistant to myelin oligodendrocyte glycoprotein (MOG) -induced experimental autoimmune encephalomyelitis (EAE). J. Mol. Neurosci. 15:2000;167-176.
    • (2000) J. Mol. Neurosci. , vol.15 , pp. 167-176
    • Offen, D.1    Kaye, J.F.2    Bernard, O.3
  • 25
    • 0032726280 scopus 로고    scopus 로고
    • Combined magnetization transfer and proton spectroscopy imaging in the assessment of pathologic brain lesions in multiple sclerosis
    • Pike G.B., De Stefano N., Narayanan S., et al. Combined magnetization transfer and proton spectroscopy imaging in the assessment of pathologic brain lesions in multiple sclerosis. Am. J. Neuroradiol. 20:1999;829-837.
    • (1999) Am. J. Neuroradiol. , vol.20 , pp. 829-837
    • Pike, G.B.1    De Stefano, N.2    Narayanan, S.3
  • 26
    • 0033958462 scopus 로고    scopus 로고
    • Glutamate excitotoxicity in a model of multiple sclerosis
    • Pitt D., Werner P., Raine C.S. Glutamate excitotoxicity in a model of multiple sclerosis. Nat. Med. 6:2000;67-70.
    • (2000) Nat. Med. , vol.6 , pp. 67-70
    • Pitt, D.1    Werner, P.2    Raine, C.S.3
  • 27
    • 0026599446 scopus 로고
    • Copolymer 1 induced inhibition of antigen-specific T-cell activation: Interference with antigen presentation
    • Racke M.K., Martin R., McFarland H., et al. Copolymer 1 induced inhibition of antigen-specific T-cell activation: interference with antigen presentation. J. Neuroimmunol. 37:1992;75-84.
    • (1992) J. Neuroimmunol. , vol.37 , pp. 75-84
    • Racke, M.K.1    Martin, R.2    McFarland, H.3
  • 28
    • 0024409098 scopus 로고
    • Axonal dystrophy as a consequence of long-term demyelination
    • Raine C.S., Cross A.H. Axonal dystrophy as a consequence of long-term demyelination. Lab. Invest. 60:1989;714-725.
    • (1989) Lab. Invest. , vol.60 , pp. 714-725
    • Raine, C.S.1    Cross, A.H.2
  • 29
    • 0036264075 scopus 로고    scopus 로고
    • Anti-inflammatory strategies to prevent axonal injury in multiple sclerosis
    • Rieckmann P., Mauser M. Anti-inflammatory strategies to prevent axonal injury in multiple sclerosis. Curr. Opin. Neurol. 15:2002;361-370.
    • (2002) Curr. Opin. Neurol. , vol.15 , pp. 361-370
    • Rieckmann, P.1    Mauser, M.2
  • 30
    • 0035853085 scopus 로고    scopus 로고
    • Vaccination for protection of retinal ganglion cells against death from glutamate cytotoxicity and ocular hypertension: Implications for glaucoma
    • Schori H., Kipnis J., Yoles E., et al. Vaccination for protection of retinal ganglion cells against death from glutamate cytotoxicity and ocular hypertension: implications for glaucoma. Proc. Natl. Acad. Sci. USA. 98:2001;3398-3403.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 3398-3403
    • Schori, H.1    Kipnis, J.2    Yoles, E.3
  • 31
    • 0032716144 scopus 로고    scopus 로고
    • Axonal degeneration in the pathogenesis of multiple sclerosis
    • Silber E., Sharief M.K. Axonal degeneration in the pathogenesis of multiple sclerosis. J. Neurol. Sci. 170:1999;11-18.
    • (1999) J. Neurol. Sci. , vol.170 , pp. 11-18
    • Silber, E.1    Sharief, M.K.2
  • 32
    • 0033963231 scopus 로고    scopus 로고
    • Autoimmune encephalomyelitis ameliorated by AMPA antagonists
    • Smith T., Groom A., Zhu B., et al. Autoimmune encephalomyelitis ameliorated by AMPA antagonists. Nat. Med. 6:2000;62-66.
    • (2000) Nat. Med. , vol.6 , pp. 62-66
    • Smith, T.1    Groom, A.2    Zhu, B.3
  • 33
    • 0031025835 scopus 로고    scopus 로고
    • Autoimmune pathogenesis of multiple sclerosis: Role of autoreactive T lymphocytes and new immunotherapeutic strategies
    • Stinissen P., Raus J., Zhang J. Autoimmune pathogenesis of multiple sclerosis: Role of autoreactive T lymphocytes and new immunotherapeutic strategies. Crit. Rev. Immunol. 17:1997;33-75.
    • (1997) Crit. Rev. Immunol. , vol.17 , pp. 33-75
    • Stinissen, P.1    Raus, J.2    Zhang, J.3
  • 34
    • 0024267426 scopus 로고
    • Specific inhibition of the T-cell response to myelin basic protein by the synthetic copolymer 1 Cop 1
    • Teitelbaum D., Aharoni R.M., Arnon R., et al. Specific inhibition of the T-cell response to myelin basic protein by the synthetic copolymer 1 Cop 1. Proc. Natl. Acad. Sci. 85:1988;9724-9728.
    • (1988) Proc. Natl. Acad. Sci. , vol.85 , pp. 9724-9728
    • Teitelbaum, D.1    Aharoni, R.M.2    Arnon, R.3
  • 35
    • 0026565595 scopus 로고
    • Synthetic copolymer 1 inhibits human T-cell lines specific for myelin basic protein
    • Teitelbaum D., Milo R., Arnon R., et al. Synthetic copolymer 1 inhibits human T-cell lines specific for myelin basic protein. Proc. Natl. Acad. Sci. 89:1992;137-141.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 137-141
    • Teitelbaum, D.1    Milo, R.2    Arnon, R.3
  • 36
    • 0029916716 scopus 로고    scopus 로고
    • Copolymer 1 inhibits chronic relapsing experimental allergic encephalomyelitis induced by proteolipid protein (PLP) peptides in mice and interferes with PLP-specific T cell responses
    • Teitelbaum D., Fridkis-Hareli M., Arnon R., et al. Copolymer 1 inhibits chronic relapsing experimental allergic encephalomyelitis induced by proteolipid protein (PLP) peptides in mice and interferes with PLP-specific T cell responses. J. Neuroimmunol. 64:1996;209-217.
    • (1996) J. Neuroimmunol. , vol.64 , pp. 209-217
    • Teitelbaum, D.1    Fridkis-Hareli, M.2    Arnon, R.3
  • 38
    • 0032576752 scopus 로고    scopus 로고
    • Axonal transection in the lesions of multiple sclerosis
    • Trapp B.D., Peterson J., Ransohoff R.M., et al. Axonal transection in the lesions of multiple sclerosis. New Engl. J. Med. 338:1998;278-285.
    • (1998) New Engl. J. Med. , vol.338 , pp. 278-285
    • Trapp, B.D.1    Peterson, J.2    Ransohoff, R.M.3
  • 39
    • 0032796747 scopus 로고    scopus 로고
    • Axonal pathology in multiple sclerosis: Relationship to neurologic disability
    • Trapp B.D., Ransohoff R., Rudick R. Axonal pathology in multiple sclerosis: relationship to neurologic disability. Curr. Opin. Neurol. 12:1999;295-302.
    • (1999) Curr. Opin. Neurol. , vol.12 , pp. 295-302
    • Trapp, B.D.1    Ransohoff, R.2    Rudick, R.3
  • 40
    • 0023214616 scopus 로고
    • COP 1 therapy for multiple sclerosis
    • Weiner H. COP 1 therapy for multiple sclerosis. New Engl. J. Med. 317:1987;442-444.
    • (1987) New Engl. J. Med. , vol.317 , pp. 442-444
    • Weiner, H.1
  • 41
    • 0034911054 scopus 로고    scopus 로고
    • Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocytes and axonal damage
    • Werner P., Pitt D., Raine C.S. Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocytes and axonal damage. Ann. Neurol. 50:2001;169-180.
    • (2001) Ann. Neurol. , vol.50 , pp. 169-180
    • Werner, P.1    Pitt, D.2    Raine, C.S.3
  • 42
    • 0036845819 scopus 로고    scopus 로고
    • Glatiramer acetate-specific T-helper 1 and 2-type cell lines produce brain derived neurotrophic factor (BDNF): Implications for multiple sclerosis therapy
    • Ziemssen T., Kumpfel T., Klinkert W.E., et al. Glatiramer acetate-specific T-helper 1 and 2-type cell lines produce brain derived neurotrophic factor (BDNF): implications for multiple sclerosis therapy. Brain. 125:2002;2381-2391.
    • (2002) Brain , vol.125 , pp. 2381-2391
    • Ziemssen, T.1    Kumpfel, T.2    Klinkert, W.E.3


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