Treatment-seeking inpatient cocaine abusers show hypothalamic dysregulation of both basal prolactin and cortisol secretion

Neuroendocrinology

Volumn 78, Issue 3, 2003, Pages 154-162

  Contoreggi, Carlo ^a   Herning, Ronald I ^a   Koeppl, Bonnie ^a   Simpson, Pippa M ^b   Negro Jr , Paulo J ^c   Fortner Burton, Carolyn ^d   Hess, Judith ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b UNIVERSITY OF ARKANSAS MEDICAL CENTER   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d United Network of Organ Sharing   (United States)

Author keywords

Abstinence; Adrenal steroids; Clinical neuroendocrinology; Cocaine; Corticotropin releasing hormone; Cortisol; Prolactin; Stress

Indexed keywords

COCAINE; DOPAMINE; HYDROCORTISONE; PROLACTIN; PROTIRELIN;

ADULT; ARTICLE; CIRCADIAN RHYTHM; COCAINE DEPENDENCE; CONTROLLED STUDY; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; HYPOPHYSIS; HYPOTHALAMUS; HYPOTHALAMUS DISEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; PROLACTIN RELEASE; STRESS; WITHDRAWAL SYNDROME;

ADULT; ANALYSIS OF VARIANCE; AREA UNDER CURVE; COCAINE-RELATED DISORDERS; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INPATIENTS; PERSONALITY ASSESSMENT; PITUITARY-ADRENAL SYSTEM; PROLACTIN; REFERENCE VALUES; SUBSTANCE ABUSE TREATMENT CENTERS; TIME FACTORS;

EID: 0141505076     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000072797     Document Type: Article

References (51)

1. Pilotte N, Sharpe L, Day E: Multiple but not acute infusions of cocaine alter the release of prolactin in male rats. Brain Res 1990;512: 107-112.
2. Baumann M, Rothman R: Effects of acute and chronic cocaine on the activity of tuber infundibular dopamine neurons on the rat. Brain Res 1993;608:175-179.
3. Gawin F, Kleber H: Neuroendocrine findings in chronic cocaine abusers: A preliminary report. Br J Psychiatry 1985;147:569-573.
4. Lee M, Bowers M, Nash J, Meltzer H: Neuroendocrine measures of dopaminergic function in chronic cocaine users. Psychiatry Res 1990;33:151-159.
5. Satel S, Price L, Palumbo J, McDougle C, Krystal J, Gawin F, Charney D, Heninger G, Kleber H: Clinical phenomenology and neurobiology of cocaine abstinence: A prospective inpatient study. Am J Psychiatry 1991;48:1712-1716.
6. Mendelson J, Teoh S, Lange U, Mello N, Weiss R, Skupny A, Ellingboe J: Anterior pituitary, adrenal, and gonadal hormones during cocaine withdrawal. Am J Psychiatry 1988;145:1094-1098.
7. Dackis C, Gold M, Davies R, Sweeney D: Bromocriptine treatment for cocaine abuse: The dopamine depletion hypothesis. International J Psychiatry Med 1986;15:125-135.
8. Cocores J, Dackis C, Gold M: Sexual dysfunction secondary to cocaine abuse. J Clin Psychiatry 1986;467:384-386.
9. Cocores J, Pottash A, Gold M, Miller N: Sexual dysfunction in abusers of cocaine and alcohol. Med Times 1987;115:103-109.
10. Ashley R: Cocaine: Its History, Uses and Effects. New York, St. Martin's Press, 1975.
11. Baumann M, Gendron, T, Becketts K, Henningfield J, Gorelick D, Rothman R: Effects of Intravenous cocaine on plasma cortisol and prolactin in human cocaine abusers. Biol Psychiatry 1994;38:751-755.
12. Habib KE, Weld KP, Rice KC, Pushkas J, Champoux M, Listwak S, Webster EL, Atkinson AJ, Schulkin J, Contoreggi C, Chrousos GP, McCann SM, Suomi SJ, Higley JD, Gold PW: Oral administration of a corticotrophin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates. Proc Natl Acad Sci USA 2000;97:6079-6084.
13. Tuomisto J, Mannisto P: Neurotransmitter regulation of anterior pituitary hormones. Pharmacol Rev 1985;37:249-328.
14. O'Connor TM, O'Halloran DJ, Shanahan F: The stress response and the hypothalamic-pituitary-adrenal axis: From molecule to melancholia. QJM 2000;93:323-333.
15. Kirkby RJ, Petchkovsky L: Chronic administration of cocaine: Effects on defaecation and adrenal hypertrophy in the rat. Neuropharmacology 1973;12:1001-1003.
16. Gold PW, Gwirtsman H, Avgerinos PC, Nieman LK, Gallucci WT, Kaye W, Jimerson D, Ebert M, Rittmaster R, Loriaux DL: Abnormal hypothalamic-pituitary-adrenal function in anorexia nervosa. Pathophysiologic mechanisms in underweight and weight-corrected patients. N Engl J Med 1986;314:1335-1342.
17. Mendelson J, Stein S: Serum cortisol levels in alcoholic and nonalcoholic subjects during experimentally induced alcohol intoxication. Psychosom Med 1966;28:616-626.
18. Mendelson J, Ogata M, Mello N: Adrenal function and alcoholism. I. Serum cortisol. Psychosom Med 1971;33:145-157.
19. Gwirtsman H, Kaye WH, George DT, Jimerson DC, Ebert MH, Gold PW: Central and peripheral ACTH and cortisol levels in anorexia nervosa and bulimia. Arch Gen Psychiatry 1989;46:61-69.
20. Gold P, Joriaus D, Roy A, Kling M, Calabrese J, Kellner C, Nieman L, Post R, Pickar D, Gallucci W, Avgerinos P, Paul S, Oldfield E, Cutler G, Chrousos G: Responses to corticotropin-releasing hormone in the hypercortisolism of depression and Cushing's disease. N Engl J Med 1986;314:1329-1335.
21. Koob GF: The role of the striatopallidal and extended amygdala systems in drug addiction. Ann NY Acad Sci 1999;877:445-460.
22. Weddington WW, Brown BS, Haertzen CA, Cone EJ, Dax EM, Herning RI, Michaelson BS: Changes in mood, craving, and sleep during short-term abstinence reported by male cocaine addicts. A controlled residential study. Arch Gen Psychiatry 1990;47:861-868.
23. Derogatis LR: SCL-90-R: Administration, Scoring and Procedures. Manual II. Baltimore, Clinical Psychometric Research, 1983, p 983.
24. Nnadi Cu, Better W, Tate K, Herning RI, Cadet JL: Contribution of substance abuse and HIV infection to psychiatric distress in inner-city African-American population. J Natl Med Assoc 2002;94:1-5.
25. Mathisen K, Evans F, Meyers K: National Institute of Mental Health Diagnostic Interview Schedule: Its history and characteristics. Hosp Commun Psychiatry 1987;33:1311-1315.
26. Rounsaville B, Gawin F, Kieber H: Interpersonal psychotherapy adapted for ambulatory cocaine abusers. Am J Drug Alcohol Abuse 1985;11:171-191.
27. Beck AT, Beamesderfer A: Assessment of depression: The depression inventory. Mod Probl Pharmacopsychiatry 1974;7:151-169.
28. Beck AT, Rial WY, Rickels K: Short form of depression inventory: Cross-validation. Psychol Rep 1974;34:1184-1186.
29. Bailar JC III, Mosteller F: Medical Uses of Statistics, ed 2. Waltham, New England Journal of Medicine Books, 1992.
30. Shavelson RJ: Statistical Reasoning for the Behavioral Sciences, ed 2. Newton, Allyn & Bacon, 1988.
31. Daley LE, Bourke GJ, McGilvray J: Interpretation and Uses of Medical Statistics, ed 4. Oxford, Blackwell Science, 1991.
32. Kranzler HR, Wallington DJ: Serum prolactin level, craving, and early discharge from treatment in cocaine-dependent patients. Am J Drug Alcohol Abuse 1992;18:187-195.
33. Elangovan N, Barbato M, Cooper T, Winsberg B: Neurohormonal and behavioral response to methylphenidate in cocaine abstinence. Psychiatry Res 1996;65:65-71.
34. Hollander E, Nunes E, DeCaria CM, Quitkin FM, Cooper T, Wager S, Klein DF: Dopaminergic sensitivity and cocaine abuse: Response to apomorphine. Psychiatry Res 1990;33:161-169.
35. Baumann M, Gendron T, Becketts K, Henningfield J, Gorelick D, Rothman R: Effects of intravenous cocaine on plasma cortisol and prolactin in human cocaine abusers. Biol Psychiatry 1995;38:751-755.
36. Eiler K, Schaefer MR, Salstrom D, Lowery R: Double-blind comparison of bromocriptine and placebo in cocaine withdrawal. Am J Drug Alcohol Abuse 1995;21:65-79.
37. McDougle CJ, Black JE, Malison RT, Zimmermann RC, Kosten TR, Heninger GR, Price LH: Noradrenergic dysregulation during discontinuation of cocaine use in addicts. Arch Gen Psychiatry 1994;51:713-719.
38. McDougle CJ, Price LH, Palumbo JM, Kosten TR, Heninger GR, Kleber HD: Dopaminergic responsively during cocaine abstinence: A pilot study. Psychiatry Res 1992;43:77-85.
39. Christensen P, Kristensen CB, Gram LF, Christensen P, Pedersen OL, Kragh-Sorensen P: Afternoon plasma cortisol in depressed patients: A measure of diagnosis or severity. Life Sci 1983;132:617-623.
40. Christensen P, Gram LF, Kragh-Sorensen P, Christensen L, Kristensen CB, Pedersen OL, Thomsen HY: Spontaneous afternoon plasma cortisol in depression. J Affect Disord 1985;8: 271-278.
41. Christensen P, Lolk A, Pedersen OL, Nielsen S, Kragh-Sorensen P, Gram LF: Afternoon plasma cortisol in relation to depression. A replication study. Acta Psychiatr Scand 1988;78:737-742.
42. Christensen P, Lolk A, Gram LF, Kragh-Sorensen P, Pedersen OL, Nielsen S: Cortisol and treatment of depression: Predictive value of spontaneous and suppressed cortisol levels and course of spontaneous plasma cortisol. Psychopharmacology (Berl) 1989;97:471-475.
43. Halbreich U, Zumoff B, Kream J, Fukushima DK: The mean 1300-1600 h plasma cortisol concentration as a diagnostic test for hypercortisolism. J Clin Endocrinol Metab 1982;54: 1262-1264.
44. Halbreich U, Asnis GM, Shindledecker R, Zumoff B, Nathan RS: Cortisol secretion in endogenous depression. I. Basal plasma levels. Arch Gen Psychiatry 1985;42:904-908.
45. Zobel AW, Nickel T, Kunzel HE, Ackl N, Sonntag A, Ising M, Holsboer F: Effects of the high-affinity corticotrophin-releasing hormone receptor 1 antagonist R121919 in major depression: The first 20 patients treated. J Psychiatr Res 2000;34:171-181.
46. Shaham Y, Erb S, Leung S, Buczek Y, Stewart J: CP-154,525, a selective, non-peptide antagonist of the corticotropin-releasing factor 1 receptor, attenuates stress-induced relapse to drug seeking in cocaine- and heroin-trained rats. Psychopharmacology (Berl) 1998;137: 184-190.
47. Shaham Y, Erb S, Stewart J: Stress-induced relapse to heroin and cocaine seeking in rats: A review. Brain Res Brain Res Rev 2000;33:13-33.
48. Valdez GR, Roberts AJ, Chan K, Davis H, Brennan M, Zorrilla EP, Koob GF: Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: Regulation by corticotrophin-releasing factor. Alcohol Clin Exp Res 2002;26:1494-1501.
49. Goeders NE, Guerin GF: Role of corticosterone in intravenous cocaine self-administration in rats. Neuroendocrinology 1996;4:337-348.
50. Broadbear JH, Winger G, Woods JH: Cocaine-reinforced responding in rhesus monkeys: Pharmacological attenuation of the hypothalamic-pituitary-adrenal axis response. J Pharmacol Exp Ther 1999;290:1347-1355.
51. Rodriguez de Fonseca F, Carrera MRA, Navarro M, Koob GF, Weiss F: Activation of corticotrophin-releasing factor in the limbic system during cannabinoid withdrawal. Science 1997; 276:2050-2054.