Adenosine protects againts angiotensin II-induced apoptosis in rat cardiocyte cultures

Molecular and Cellular Biochemistry

Volumn 252, Issue 1-2, 2003, Pages 133-139

  Goldenberg, Ilan ^a   Shainberg, Asher ^b   Jacobson, Kenneth A ^c   Shneyvays, Vladimir ^b   Grossman, Ehud ^a  

^a SHEBA MEDICAL CENTER   (Israel)

^b BAR ILAN UNIVERSITY   (Israel)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

A1 and A3 adenosine receptors; Angiotensin II; Apoptosis; Cardiomyocytes; Feulgen and TUNEL stainings

Indexed keywords

2 CHLORO 6 N CYCLOPENTYLADENOSINE; 6 N (3 IODOBENZYL)ADENOSINE 5' N METHYLCARBOXAMIDE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR AGONIST; ANGIOTENSIN; CALCIUM ION; ANGIOTENSIN II; CALCIUM;

AGE; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXPOSURE; HEART CELL CULTURE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; NEWBORN; NONHUMAN; RAT; TIME; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; HEART; HEART MUSCLE; METABOLISM; NICK END LABELING; SPRAGUE DAWLEY RAT;

ANIMALIA;

ADENOSINE; ANGIOTENSIN II; ANIMALS; APOPTOSIS; CALCIUM; CELLS, CULTURED; HEART; IN SITU NICK-END LABELING; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A3;

EID: 0141505060     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025551229566     Document Type: Article

References (29)

1. Narula J, Haider N, Virmani R, DiSalvo TG, Kolodgie FD, Hajjar RJ, Schmidt U, Semigran MJ, Dec GW, Khaw BA: Apoptosis in myocytes in end-stage heart failure. N Engl J Med 335: 1182-1189, 1996
2. Olivetti G, Abbi R, Quaini F, Kajstura J, Cheng W, Nitahara JA, Quaini E, DiLoreto C, Beltrami CA, Krajewski S, Reed JC, Anversa P: Apoptosis in the failing human heart. N Engl J Med 336: 1131-1141, 1997
3. Moe GW, Naik G, Konig A, Lu X, Feng Q: Early and persistent activation of myocardial apoptosis, bax and caspases: Insights into mechanisms of progression of heart failure. Pathophysiology 8: 183-192, 2002
4. Olivetti G, Quaini F, Sala R, Lagrasta C, Corradi D, Bonacina E, Gambert SR, Cigola E, Anversa P: Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart. J Mol Cell Cardiol 28: 2005-2016, 1996
5. Cigola E, Kajstura J, Li B, Meggs LG, Anversa P: Angiotensin II activates programmed myocyte cell death in vitro. Exp cell Res 231: 363-371, 1997
6. Kajstura J, Cigola E, Malhotra A, Li P, Cheng W, Meggs LG, Anversa P: Angiotensin II induces apoptosis of adult ventricular myocytes in vitro. J Mol Cell Cardiol 29: 859-870, 1997
7. Diez J, Panizo A, Hemandez M, Vega F, Sola I, Fortuno MA, Pardo J: Cardiomyocyte apoptosis and cardiac angiotensin-converting enzyme in spontaneously hypertensive rats. Hypertension 30: 1029-1034, 1997
8. Konstam MA, Kronenberg MW, Rousseau MF, Udelson JE, Melin J, Stewart D, Dolan N, Edens TR, Ahn S, Kinan D: Effects of the angiotensin converting enzyme inhibitor enalapril on the long-term progression of left ventricular dilatation in patients with asymptomatic systolic dysfunction. SOLVD (studies of left ventricular dysfunction) investigators. Circulation 88: 2277-2283, 1993
9. Pitt B: Use of converting enzyme inhibitors in patients with asymptomatic left ventricular dysfunction. J Am Coll Cardiol 22: 158A-161A, 1993
10. Cook JR, Glick HA, Gerth W, Kinosian B, Kostis JB: The cost and cardioprotective effects of enalapril in hypertensive patients with left ventricular dysfunction. Am J Hypertens 11: 1433-1441, 1998
11. Goldenberg I, Grossman E, Jacobson KA, Shneyvays V, Shainberg A: Angiotensin II-induced apoptosis in rat cardiomyocyte culture: A possible role of AT1 and AT2 receptors. J Hypertens 19: 1681-1689, 2001
12. Shryock JC, Belardinelli L: Adenosine and adenosine receptors in the cardiovascular system: Biochemistry, physiology, and pharmacology. Am J Cardiol 79: 2-10, 1997
13. 1 analogue and ischemic preconditioning in isolated rabbit hearts. Ann Thorac Surg 60: 1698-1703, 1995
14. 3 receptors during prolonged simulated ischemia. Am J Physiol 273: H501-H505, 1997
15. 3 receptors mediates preconditioning of isolated cardiac myocytes. Eur J Pharmacol 320: 241-248, 1997
16. 3 receptor activation during hypoxia in isolated rat cardiac myocytes. Mol Cell Biochem 217: 143-152, 2001
17. 1 receptor activation maintains rabbit myocardium in a preconditioned state. J Am Coll Cardiol 31: 1142-1149, 1998
18. Funaya H, Kitakaze M, Node K, Minamino T, Komamura K, Hori M: Plasma adenosine levels increase in patients with chronic heart failure. Circulation 18: 1363-1365, 1997
19. Kitakaze M, Minamino T, Node K, Koretsune Y, Komamura K, Funaya H, Kuzuya T, Hori M: Elevation of plasma adenosine levels may attenuate the severity of chronic heart failure. Cardiovasc Drugs Ther 12: 307-309, 1998
20. Kitakaze M, Hori M: Adenosine therapy: A new approach to chronic heart failure. Expert Expert Opin Invest Drugs 9: 2519-2535, 2000
21. 3 adenosine receptor agonist. Exp Cell Res 243: 383-397, 1998
22. Wu C-F, Bishopric NH, Pratt RE: Atrial natriuretic peptide induces apoptosis in neonatal rat cardiac myocytes. J Biol Chem 272: 14860-14866, 1997
23. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450, 1985
24. Mukoyama M, Nakajima M, Horiuchi M, Sasamura H, Pratt RE, Dzau VJ: Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors. J Biol Chem 268: 24539-24542, 1993
25. Stoll M, Unger T: Angiotensin and its AT2 receptor: New insights into an old system. Regul Pept 99: 175-182, 2001
26. Traynor T, Yang T, Huang YG, Arend L, Oliverio MI, Coffman T, Briggs JP, Schnermann J: Inhibition of adenosine-1 receptor-mediated preglomerular vasoconstriction in AT1A receptor-deficient mice. Am J Physiol 275: F922-F927, 1998
27. Weihprecht H, Lorenz JN, Briggs JP, Schnermann J: Synergistic effects of angiotensin and adenosine in the renal microvasculature. Am J Physiol 266: F227-F239, 1994
28. Liu Y, Tsuchida A, Cohen MV, Downey JM: Pretreatment with angiotensin II activates protein kinase C and limits myocardial infarction in isolated rabbit hearts. J Mol Cell Cardiol 27: 883-892, 1995
29. Shneyvays V, Mamedova L, Zinman T, Jacobson K, Shainberg A: Activation of A(3) adenosine receptor protects against doxorubicin-induced cardiotoxicity. J Mol Cell Cardiol 33: 1249-1261, 2001