Predominant intracellular expression of CXCR4 and CCR5 in purified primary trophoblast cells from first trimester and term human placentae

American Journal of Reproductive Immunology

Volumn 50, Issue 4, 2003, Pages 291-301

  Maldonado Estrada, Juan ^a,b   Menu, Elisabeth ^a,c   Roques, Pierre ^d   Vaslin, Bruno ^d   Dautry Varsat, Alice ^c   Barré Sinoussi, Françoise ^c   Chaouat, Gérard ^a  

^a HÔPITAL ANTOINE BÉCLÈRE   (France)

^b UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^c INSTITUT PASTEUR   (France)

^d INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

Author keywords

Cell surface molecules; Chemokine receptors; Intracellular expression; Trophoblast cells

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4;

ARTICLE; CELL ISOLATION; CELL LEVEL; CELL SURFACE; CESAREAN SECTION; CONTROLLED STUDY; FIRST TRIMESTER PREGNANCY; FLOW CYTOMETRY; GESTATIONAL AGE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INTRACELLULAR SPACE; PLACENTA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PURIFICATION; TROPHOBLAST;

CELL COMPARTMENTATION; CELL MEMBRANE; CELL SEPARATION; FEMALE; FLOW CYTOMETRY; HUMANS; INTRACELLULAR FLUID; MICROSCOPY, FLUORESCENCE; PLACENTA; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, THIRD; RECEPTORS, CCR5; RECEPTORS, CXCR4; TROPHOBLASTS;

EID: 0141459151     PISSN: 87558920     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0897.2003.00084.x     Document Type: Article

References (43)

1. Murphy PM, Baggliolini M, Charo IF, Hebert CA, Horuk R, Matsushima K, Miller LH, Oppenheim JJ, Power CA: International Union of Pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev 2000; 52: 145-176.
2. Zlotnik A, Yoshie O: Chemokines: A new classification system and its role in immunity. Immunity 2000; 12: 121-127.
3. Mognetti B, Moussa M, Croitoru J, Menu E, Dormont D, Roques P, Chaouat G: HIV-1 co-receptor expression on trophoblastic cells from early placentas and permissivity to infection by several HIV-1 primary isolates. Clin Exp Immunol 2000; 119:486-492.
4. Mognetti B, Menu E, Colognesi C, Roques P, Barré-Sinoussi F, Chaouat G, Scarlatti G: Studies on permissivity of human trophoblastic cells to in vitro infection by several primary natural HIV-1 isolates. HIV pathogenesis and treatment. Plark City, Utah, Keystone Symposia, 1998.
5. Fear WR, Kesson AM, Naif H, Lynch GW, Cunningham AL: Differential tropism and chemokine receptor expression of human immunodeficiency virus type 1 in neonatal monocytes, monocyte-derived macrophages, and placental macrophages. J Virology 1998; 72: 1334-144.
6. Douglas GC, Thirkill TL, Sideris V, Rabieh M, Trollinger D, Nuccitelli R: Chemokine receptor expression by human syncytiotrophoblast. J Reprod Immunol 2001; 49:97-114.
7. Patterson BK, Behbahani H, Kabat WJ, Sullivan Y, O'Gorman MR, Landay A, Flener Z, Khan N, Yogev R, Andersson J: Leukemia inhibitory factor inhibits HIV-1 replication and is upregulated in placentae from non-transmitting women. J Clin Invest 2001; 107:287-294.
8. Ishii M, Hayakawa S, Suzuki MK, Yoshino N, Honda M, Nishinarita S, Chishima F, Nagaishi M, Satoh K: Expression of functional chemokine receptors of human placental cells. Am J Reprod Immunol 2000; 44:365-373.
9. Athanassakis I, Papadimitriou L, Koumantakis E, Vasiliadis S: Th1- and Th2-type lymphokine-assisted induction and release of chemokine receptors from primary human trophoblast cells. Hum Immunol 2000;61:651-657.
10. Cervar M, Blaschitz A, Dohr G, Desoye G: Paracrine regulation of distinct trophoblast functions by placental macrophages. Cell Tissue Res 1999; 295:297-305.
11. Torres G, Garcia V, Sanchez E, Segarra A, Patterson BK, Melendez-Guerrero LM: Expression of the HIV-1 co-receptors CCR5 and CXCR4 on placental macrophages and the effect of IL-10 on their expression. Placenta 2001; Suppl. A: S29.
12. Corcione A, Ottonello L, Tortolina G, Facchetti P, Airoldi I, Guglielmino R, Dadati P, Truini M, Sozzani S, Dallegri F, Pistoia V: Stromal cell-derived factor-1 as a chemoattractant for follicular center lymphoma B cells. J Natl Cancer Inst 2000; 92:628-635.
13. Zaslaver A, Feniger-Barish R, Ben-Baruch A: Actin filaments are involved in the regulation of trafficking of two closely related chemokine receptors, CXCR1 and CXCR2. J Immunol 2001; 166:1272-1284.
14. Coulomb-L'Hermine A, Emilie D, Durand-Gasselin I, Galanaud P, Chaouat G: SDF-1 production by placental cells: A potential mechanism of inhibition of mother-to-foetus HIV transmission. AIDS Res Hum Retroviruses 2000; 16:1097-1098.
15. Bockaert J, Pin JP. Molecular tinkering of G protein-coupled receptors: An evolutionary success. EMBO J 1999; 18:1723-1729.
16. Amara A, Gall SL, Schwartz O, Salamero J, Montes M, Loetscher P, Baggliolini M, Virelizier JL, Arenza-Seisdedos F: HIV coreceptor downregulation as antiviral principle: SDF-1a-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication. J Exp Med 1997; 186:139-146.
17. Frster R, Kremmer E, Schubal A, Briefeld D, Kleindchmidt A, Nerl C, Bernhardt G, Lipp M: Intracellular and surface expression of the HIV-1 coreceptor CXCR4/Fusin on various leukocyte subsets: Rapid internalization and recycling upon activation. J Immunol 1998; 160:1522-1531.
18. Wang J, Guan E, Rodriquez G, Calvert V, Avarez R, Norcross MA: Role of tyrosine phosphorylation in ligand-independent sequestration of CXCR4 in human primary monocytes-macrophages. J Biol Chem 2001; 276:49236-49243.
19. Signoret N, Oldridge J, Pelchen-Matthews A, Klasse PJ, Tran T, Brass LF, Rosenkilde MM, Schwartz TW, Holmes W, Dallas W, Luther MA, Wells TN, Hoxie JA, Marsh M: Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4. J Cell Biol 1997; 139:651-664.
20. Tarasova NI, Stauber RH, Michejda CJ: Spontaneous and ligand-induced trafficking of CXC-chemokine receptor 4. J Biol Chem 1998; 273:15883-15886.
21. Kliman HJ, Nestler JE, Sermasi E, Sanger J, Strauss JF III. Purification, characterization and in vitro differentiation of cytotrophoblasts from human term placenta. Endocrinology 1986; 118:1567-1582.
22. Moussa M, Roques P, Fievet N, Menu E, Maldonado-Estrada JG, Brunerie J, Frydman R, Fdritel X, Herve F, Chaouat G: Placental cytokine and chemokine production in HIV-1-infected woman: Trophoblast cells show a different pattern compared to cells from HIV-negative woman. Clin Exp Immunol 2001; 125:455-464.
23. Haigh T, Chen CP, Jones CJP, Aplin JD: Studies of mesenchymal cells from 1st trimester human placenta: Expression of cytokeratin outside the trophoblast lineage. Placenta 1999; 20:615-625.
24. Blaschitz A, Weiss U, Dohr G, Desoye G: Antibody reaction patterns in first trimester placenta: Implications for trophoblast isolation and purity screening. Placenta 2000; 21:733-741.
25. King A, Burrows TD, Hiby SE, Bowen JM, Joseph S, Verma S, Lim PB, Gardner L, Le Bouteiller P, Ziegler A, Uchanska-Ziegler B, Loke YW: Surface expression of HLA-C antigen by human extravillous trophoblast. Placenta 2000; 21:376-387.
26. Al-Harthi L, Guilbert LJ, Hoxie JA, Landay A: Trophoblasts are productively infected by CD4-independent isolate of HIV type1. AIDS Res Hum Retroviruses 2002; 18:13-17.
27. Guilbert LJ, Winkler-Lowen B, Sherburne R, Rote NS, Li H, Morrish DW. Preparation and functional characterization of villous cytotrophoblasts free of syncytial fragments. Placenta 2002; 23:175-183.
28. Tscherning-Casper C, Vodros D, Menu E, Aperia K, Fredriksson R, Dolcini G, Chaouat G, Barre-Sinoussi F, Albert J, Fenyo EM. Coreceptor usage of HIV-1 isolates representing different genetic subtypes obtained from pregnant Cameroonian women. European network for in utero transmission of HIV-1. J Acquir Immune Defic Syndr 2000; 24:1-9.
29. Emar H, Sutil A, Lieb M, Morelon E, Hellio R, Dautry-Varsat A: Endocytosis of interleukin 2 receptors in human T lymphocytes: Distinct intracellular localization and fate of the receptor alpha, beta, and gamma chains. J Cell Biol 1995; 129:55-64.
30. Ptgens AJ, Gaus G, Frank HG, Kaufmann P: Characterization of trophoblast cell isolations by a modified flow cytometry assay. Placenta 2001; 22:251-255.
31. Frank HG, Genbacev O, Blaschitz A, Chen CP, Clarson L, Evain-Brion D, Gardner L, Malek A, Morrish D, Loke YW, Tarrade A: Cell culture models of human trophoblast-primary culture of trophoblast-a workshop report. Placenta 2000; Suppl. A:S120.
32. Jokhi PP, King A, Loke YW: Reciprocal expression of epidermal growth factor receptor (EGF-R) and c-erbB2 by non-invasive and invasive human trophoblast populations. Cytokine 1994; 6:433-442.
33. King A, Boocock C, Sharkey AM, Gardner L, Beretta A, Siccardi AG, Loke YW: Evidence for the expression of HLA A-C class I mRNA and protein by human first trimester trophoblast. J Immunol 1996; 156:2068-2076.
34. Signoret N, Pelchen-Matthews A, Mack M, Proudfoot AE, Marsh M. Endocytosis and recycling of the HIV coreceptor CCR5. J Cell Biol 2000; 151:1281-1294.
35. Signoret N, Rosenkilde MM, Klasse PJ, Schwartz TW, Malim MH, Hoxie JA, Marsh M. Differential regulation of CXCR4 and CCR5 endocytosis. J Cell Sci 1998; 111:2819-2830.
36. Steinberger P, Andris-Widhopf J, Bühler B, Torbett BE, Barbas CF III: Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion. Proc Natl Acad Sci USA 2000; 97:805-810.
37. Lagaye S, Derrien M, Menu E, Coito C, Tresoldi E, Mauclere P, Scarlatti G, Chaouat G, Barre-Sinoussi F, Bomsel M: Cell-to-cell contact results in a selective translocation of maternal human immunodeficiency virus type 1 quasispecies across a trophoblastic barrier by both transcytosis and infection. J Virol 2001; 75:4780-4791.
38. Bischof P, Meisser A, Campana A: Biochemistry and molecular biology of trophoblast invasion. Ann N Y Acad Sci 2001; 943:157-162.
39. Bai X, Chen JD, Yang AG, Torti F, Chen SY: Genetic co-inactivation of macrophage- and T-tropic HIV-1 chemokine coreceptors CCR-5 and CXCR-4 by intrakines. Gene Ther 1998; 5:984-994.
40. Percherancier Y, Plenchenault T, Valenzuela-Fernandez A, Virelizier JL, Arenzana-Seisdedos F, Bechelerie F: Palmitoylation-dependent control of degradation, life span, and membrane expression of CCR5 receptor. J Biol Chem 2001; 276:31936-31944.
41. Vives A, Balasch J, Yague J, Quinto L, Ordi J, Vanrell JA: Type-1 and type-2 cytokines in human decidual tissue and trophoblasts from normal and abnormal pregnancies detected by reverse transcriptase polymerase chain reaction (RT-PCR). Am J Reprod Immunol 1999;42:361-368.
42. Moussa M, Mognetti B, Dubanchet S, Menu E, Roques P, Dormont D, Barre-Sinoussi F, Chaouat G: Expression of β chemokines in explants and trophoblasts from early and term human placenta. Am J Reprod Immunol 2001; 46:309-317.
43. Gupta SK, Pillarisetti K, Aiyar N: CXCR4 undergoes complex lineage and inducing agent-dependent dissociation of expression and functional responsiveness to SDF-1 alpha during myeloid differentiation. J Leuk Biol 2001; 70:431-438.