Gastrin reverses established cholangiocyte proliferation and enhanced secretin-stimulated ductal secretion of BDL rats by activation of apoptosis through increased expression of Ca2+-dependent PKC isoforms

Liver International

Volumn 23, Issue 2, 2003, Pages 78-88

  Glaser, Shannon ^a   Alvaro, Domenico ^b   Ueno, Yoshiyuki ^c   Francis, Heather ^a   Marzioni, Marco ^a   Phinizy, Jo Lynne ^a   Baumann, Brandy ^a   Mancino, Maria Grazia ^b   Venter, Julie ^a   LeSage, Gene ^a   Alpini, Gianfranco ^a,d  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d Central Texas Veterans Health System   (United States)

Author keywords

Bicarbonate secretion; Bile flow; cAMP; Cholangiocytes; Growth; Intrahepatic biliary epithelium; Morphometry; PCNA

Indexed keywords

CALCIUM ION; CYCLIC AMP; CYCLINE; CYTOKERATIN 19; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GASTRIN; ISOENZYME; LIPOCORTIN 5; PROTEIN KINASE C; SECRETIN; BIOLOGICAL MARKER; CALCIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BILE DUCT; BILE DUCT LIGATION; BILE FLOW; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME RELEASE; HORMONAL REGULATION; HORMONE INHIBITION; IMMUNOBLOTTING; MALE; MINIPUMP; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; RAT; ANIMAL; BIOSYNTHESIS; CELL DIVISION; COMPARATIVE STUDY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; FISCHER 344 RAT; LIGATION; METABOLISM; PHYSIOLOGY; STATISTICS;

ANIMALS; APOPTOSIS; BILE DUCTS; BIOLOGICAL MARKERS; CALCIUM; CELL DIVISION; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GASTRINS; ISOENZYMES; LIGATION; MALE; MODELS, ANIMAL; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN KINASE C; RATS; RATS, INBRED F344; SECRETIN; STATISTICS;

EID: 0043288615     PISSN: 14783223     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0676.2003.00814.x     Document Type: Article

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