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Volumn 93, Issue 2, 2003, Pages 87-90

All in the family: VEGF-B joins the ranks of proangiogenic cytokines

Author keywords

Akt; Angiogenesis; Vascular endothelial growth factor receptor 1; Vascular endothelial growth factor B; VEGFR 1

Indexed keywords

ADENOVIRUS VECTOR; ANGIOGENIC FACTOR; ANGIOGENIC GROWTH FACTOR; CYTOKINE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 5; HYPOXIA INDUCIBLE ENDOTHELIAL CELL MITOGEN; MITOGENIC AGENT; NEUROPILIN 1; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLACENTAL GROWTH FACTOR; PROTEIN KINASE B; RECOMBINANT PROTEIN; SCATTER FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN B; VASCULOTROPIN B165; VASCULOTROPIN B167; VASCULOTROPIN B186; VASCULOTROPIN C; VASCULOTROPIN D; VASCULOTROPIN E; VASCULOTROPIN RECEPTOR 1;

EID: 0043269282     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000084992.10766.36     Document Type: Editorial
Times cited : (11)

References (49)
  • 1
    • 0003406415 scopus 로고    scopus 로고
    • Dallas, Tex: American Heart Association
    • Heart and Stroke Statistical Update. Dallas, Tex: American Heart Association; 2002.
    • (2002) Heart and Stroke Statistical Update
  • 2
    • 0002448646 scopus 로고
    • What is the natural history of a critically ischemic patient with and without his leg?
    • Greenhalgh RM, Jamieson CW, Nicolaides AN, eds. Philadelphia, Pa: WB Saunders Co
    • Dormandy JA, Thomas PRS. What is the natural history of a critically ischemic patient with and without his leg? In: Greenhalgh RM, Jamieson CW, Nicolaides AN, eds. Limb Salvage and Amputation for Vascular Disease. 11th ed. Philadelphia, Pa: WB Saunders Co; 1988:11-26.
    • (1988) Limb Salvage and Amputation for Vascular Disease. 11th Ed. , pp. 11-26
    • Dormandy, J.A.1    Thomas, P.R.S.2
  • 3
    • 0008457727 scopus 로고    scopus 로고
    • Critical limb ischemia
    • Tooke JE, Lowe GDO, eds. London, UK: Arnold
    • Dormandy JA, Loh A. Critical limb ischemia. In: Tooke JE, Lowe GDO, eds. A Textbook of Vascular Medicine. London, UK: Arnold; 1996:221-236.
    • (1996) A Textbook of Vascular Medicine , pp. 221-236
    • Dormandy, J.A.1    Loh, A.2
  • 4
    • 0026262133 scopus 로고
    • European Working Group on Critical Leg Ischemia: Second European consensus document on chronic critical leg ischemia
    • European Working Group on Critical Leg Ischemia: second European consensus document on chronic critical leg ischemia. Circulation. 1991;84(suppl IV):IV-1-IV-26.
    • (1991) Circulation , vol.84 , Issue.SUPPL. IV
  • 5
    • 0037058881 scopus 로고    scopus 로고
    • Biological revascularization and the interventional molecular cardiologist: Bypass for the next generation
    • Losordo DW, Kawamoto A. Biological revascularization and the interventional molecular cardiologist: bypass for the next generation. Circulation. 2002;106:3002-3005.
    • (2002) Circulation , vol.106 , pp. 3002-3005
    • Losordo, D.W.1    Kawamoto, A.2
  • 6
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau W. Mechanisms of angiogenesis. Nature. 1997;386:671-674.
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 7
    • 0033134604 scopus 로고    scopus 로고
    • Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization
    • Isner JM, Asahara T. Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization. J Clin Invest. 1999;103:1231-1236.
    • (1999) J Clin Invest , vol.103 , pp. 1231-1236
    • Isner, J.M.1    Asahara, T.2
  • 8
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med. 1995;1:27-30.
    • (1995) Nat Med , vol.1 , pp. 27-30
    • Folkman, J.1
  • 9
    • 0032710319 scopus 로고    scopus 로고
    • Clinical applications of angiogenic growth factors and their inhibitors
    • Ferrara N, Alitalo K. Clinical applications of angiogenic growth factors and their inhibitors. Nat Med. 1999;5:1359-1364.
    • (1999) Nat Med , vol.5 , pp. 1359-1364
    • Ferrara, N.1    Alitalo, K.2
  • 10
    • 0029004025 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogcnesis
    • Dvorak HF, Brown LF, Detmar M, Dvorak AM. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogcnesis. Am J Pathol. 1995;146:1029-1039.
    • (1995) Am J Pathol , vol.146 , pp. 1029-1039
    • Dvorak, H.F.1    Brown, L.F.2    Detmar, M.3    Dvorak, A.M.4
  • 11
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara, N, Davis-Smith T. The biology of vascular endothelial growth factor. Endocrinol Rev. 1997;18:4-25.
    • (1997) Endocrinol Rev , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smith, T.2
  • 12
    • 0032890361 scopus 로고    scopus 로고
    • Structure, expression and receptor-binding properties of novel vascular endothelial growth factors
    • Eriksson U, Alitalo K. Structure, expression and receptor-binding properties of novel vascular endothelial growth factors. Curr Top Microbiol Immunol. 1999;237:41-57.
    • (1999) Curr Top Microbiol Immunol , vol.237 , pp. 41-57
    • Eriksson, U.1    Alitalo, K.2
  • 13
    • 0033047875 scopus 로고    scopus 로고
    • VEGFs, receptors and angiogenesis
    • Veikkola T, Alitalo K. VEGFs, receptors and angiogenesis. Semin Cancer Biol. 1999;9:211-220.
    • (1999) Semin Cancer Biol , vol.9 , pp. 211-220
    • Veikkola, T.1    Alitalo, K.2
  • 14
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med. 1971;285:1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 15
    • 0043177668 scopus 로고    scopus 로고
    • Bevacizumab (avastin, a monoclonal antibody to vascular endothelial growth factor) prolongs survival as front-line therapy for advanced colorectal cancer (CRC): Results of a phase III trial of bevacizumab in combination with bolus IFL (irinotecan, 5-fluorouracil, leucovorin) as first line therapy in subjects with metastatic CRC
    • Chicago, Ill
    • Hurwitz H, Fehrenbacher L, Cartwright T, et al. Bevacizumab (avastin, a monoclonal antibody to vascular endothelial growth factor) prolongs survival as front-line therapy for advanced colorectal cancer (CRC): results of a phase III trial of bevacizumab in combination with bolus IFL (irinotecan, 5-fluorouracil, leucovorin) as first line therapy in subjects with metastatic CRC. In: 39th Annual Meeting of the American Society of Clinical Oncology. Chicago, Ill;2003.
    • (2003) 39th Annual Meeting of the American Society of Clinical Oncology
    • Hurwitz, H.1    Fehrenbacher, L.2    Cartwright, T.3
  • 16
    • 0028344109 scopus 로고
    • Therapeutic angiogenesis: A single intra-arterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hindlimb model
    • Takeshita S, Zheng LP, Brogi E, Kearney M, Pu LQ, Bunting S, Ferrara N, Symes JF, Isner JM. Therapeutic angiogenesis: a single intra-arterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hindlimb model. J Clin Invest. 1994;93:662-670.
    • (1994) J Clin Invest , vol.93 , pp. 662-670
    • Takeshita, S.1    Zheng, L.P.2    Brogi, E.3    Kearney, M.4    Pu, L.Q.5    Bunting, S.6    Ferrara, N.7    Symes, J.F.8    Isner, J.M.9
  • 22
    • 0031797530 scopus 로고    scopus 로고
    • Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: Preliminary clinical results
    • discussion 73-75
    • Isner JM, Baumgartner I, Rauh G, Schainfeld R, Blair R, Manor O, Razvi S, Symes JF. Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: preliminary clinical results. J Vasc Surg. 1998;28:964-973; discussion 73-75.
    • (1998) J Vasc Surg , vol.28 , pp. 964-973
    • Isner, J.M.1    Baumgartner, I.2    Rauh, G.3    Schainfeld, R.4    Blair, R.5    Manor, O.6    Razvi, S.7    Symes, J.F.8
  • 24
    • 0037197740 scopus 로고    scopus 로고
    • Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia
    • Losordo DW, Vale PR, Hendel RC, Milliken CE, Fortuin FD, Cummings N, Schatz RA, Asahara T, Isner JM, Kuntz RE. Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia. Circulation. 2002;105:2012-2018.
    • (2002) Circulation , vol.105 , pp. 2012-2018
    • Losordo, D.W.1    Vale, P.R.2    Hendel, R.C.3    Milliken, C.E.4    Fortuin, F.D.5    Cummings, N.6    Schatz, R.A.7    Asahara, T.8    Isner, J.M.9    Kuntz, R.E.10
  • 30
    • 0032954241 scopus 로고    scopus 로고
    • Localization of VEGF-B in the mouse embryo suggests a paracrine role of the growth factor in the developing vasculature
    • Aase K, Lymboussaki A, Kaipainen A, Olofsson B, Alitalo K, Eriksson U. Localization of VEGF-B in the mouse embryo suggests a paracrine role of the growth factor in the developing vasculature. Dev Dyn. 1999;215:12-25.
    • (1999) Dev Dyn , vol.215 , pp. 12-25
    • Aase, K.1    Lymboussaki, A.2    Kaipainen, A.3    Olofsson, B.4    Alitalo, K.5    Eriksson, U.6
  • 34
    • 0033566938 scopus 로고    scopus 로고
    • Multiple developmental roles of VEGF suggested by a LacZ-tagged allele
    • Miquerol L, Gertsenstein M, Harpal K, Rossant J, Nagy A. Multiple developmental roles of VEGF suggested by a LacZ-tagged allele. Dev Biol. 1999;212:307-322.
    • (1999) Dev Biol , vol.212 , pp. 307-322
    • Miquerol, L.1    Gertsenstein, M.2    Harpal, K.3    Rossant, J.4    Nagy, A.5
  • 35
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell. 1998;92:735-745.
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 37
    • 0032764427 scopus 로고    scopus 로고
    • Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice
    • Fong GH, Zhang L, Bryce DM, Peng J. Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice. Development. 1999;126:3015-3025.
    • (1999) Development , vol.126 , pp. 3015-3025
    • Fong, G.H.1    Zhang, L.2    Bryce, D.M.3    Peng, J.4
  • 38
    • 0032482978 scopus 로고    scopus 로고
    • Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
    • Hiratsuka S, Minowa O, Kuno J, Noda T, Shibuya M. Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci USA. 1998;95:9349-9354.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9349-9354
    • Hiratsuka, S.1    Minowa, O.2    Kuno, J.3    Noda, T.4    Shibuya, M.5
  • 39
    • 0029790466 scopus 로고    scopus 로고
    • The second immunoglobulin-like domain of the VEGF tyrosine kinase receptor Flt-1 determines ligand binding and may initiate a signal transduction cascade
    • Davis-Smyth T, Chen H, Park J, Presta LG, Ferrara N. The second immunoglobulin-like domain of the VEGF tyrosine kinase receptor Flt-1 determines ligand binding and may initiate a signal transduction cascade. EMBO J. 1996;15:4919-4927.
    • (1996) EMBO J , vol.15 , pp. 4919-4927
    • Davis-Smyth, T.1    Chen, H.2    Park, J.3    Presta, L.G.4    Ferrara, N.5
  • 40
    • 0028134936 scopus 로고
    • Placenta growth factor: Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR
    • Park JE, Chen HH, Winer J, Houck KA, Ferrara N. Placenta growth factor: potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J Biol Chem. 1994;269:25646-25654.
    • (1994) J Biol Chem , vol.269 , pp. 25646-25654
    • Park, J.E.1    Chen, H.H.2    Winer, J.3    Houck, K.A.4    Ferrara, N.5
  • 43
    • 0034254273 scopus 로고    scopus 로고
    • A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3′-kinase activation and endothelial cell migration
    • Gille H, Kowalski J, Yu L, Chen H, Pisabarro MT, Davis-Smyth T, Ferrara N. A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3′-kinase activation and endothelial cell migration. EMBO J. 2000;19:4064-4073.
    • (2000) EMBO J , vol.19 , pp. 4064-4073
    • Gille, H.1    Kowalski, J.2    Yu, L.3    Chen, H.4    Pisabarro, M.T.5    Davis-Smyth, T.6    Ferrara, N.7
  • 44
    • 0032554778 scopus 로고    scopus 로고
    • Flt-1, a receptor for vascular endothelial growth factor, has transforming and morphogenic potentials
    • Mara Y, Yamaguchi S, Shibuya M. Flt-1, a receptor for vascular endothelial growth factor, has transforming and morphogenic potentials. Oncogene. 1998;16:2585-2595.
    • (1998) Oncogene , vol.16 , pp. 2585-2595
    • Mara, Y.1    Yamaguchi, S.2    Shibuya, M.3
  • 45
    • 18244421981 scopus 로고    scopus 로고
    • Young adult bone marrow-derived endothelial precursor cells restore aging-impaired cardiac angiogenic function
    • Edelberg JM, Tang L, Hattori K, Lyden D, Rafii S. Young adult bone marrow-derived endothelial precursor cells restore aging-impaired cardiac angiogenic function. Circ Res. 2002;90:e89-e93.
    • (2002) Circ Res , vol.90
    • Edelberg, J.M.1    Tang, L.2    Hattori, K.3    Lyden, D.4    Rafii, S.5
  • 47
    • 0029562097 scopus 로고
    • Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs
    • Kitsukawa T, Shimono A, Kawakami A, Kondoh H, Fujisawa H. Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development. 1995;121:4309-4318.
    • (1995) Development , vol.121 , pp. 4309-4318
    • Kitsukawa, T.1    Shimono, A.2    Kawakami, A.3    Kondoh, H.4    Fujisawa, H.5
  • 48
    • 0032515047 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway: Requirement for Flk-1/KDR activation
    • Gerber HP, McMurtrey A, Kowalski J, Yan M, Keyt BA, Dixit V, Ferrara N. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway: requirement for Flk-1/KDR activation. J Biol Chem. 1998;273:30336-30343.
    • (1998) J Biol Chem , vol.273 , pp. 30336-30343
    • Gerber, H.P.1    McMurtrey, A.2    Kowalski, J.3    Yan, M.4    Keyt, B.A.5    Dixit, V.6    Ferrara, N.7
  • 49
    • 4243451583 scopus 로고    scopus 로고
    • Akt mediates the cell survival effects of vascular endothelial growth factor
    • Abstract
    • Fujio Y, Mano T, Takahashi T, Walsh K. Akt mediates the cell survival effects of vascular endothelial growth factor. Circulation. 1998;98(suppl I):I-463. Abstract.
    • (1998) Circulation , vol.98 , Issue.SUPPL. I
    • Fujio, Y.1    Mano, T.2    Takahashi, T.3    Walsh, K.4


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